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    SCL33 SC35-like splicing factor 33 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841976, updated on 3-Nov-2024

    Summary

    Official Symbol
    SCL33
    Official Full Name
    SC35-like splicing factor 33
    Primary source
    TAIR:AT1G55310
    Locus tag
    AT1G55310
    See related
    Araport:AT1G55310
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    At-SCL33; ATSCL33; F7A10.26; F7A10.27; F7A10_26; SC35-like splicing factor 33; SC35-LIKE SPLICING FACTOR 33; SR33
    Summary
    Encodes a SR spliceosome protein that is localized to nuclear specks, interacts with SR45 and the U1-70K protein of the U1 snRNP, has sequence similar to human SC35 protein. Barta et al (2010) have proposed a nomenclature for Serine/Arginine-Rich Protein Splicing Factors (SR proteins): Plant Cell. 2010, 22:2926.
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    Genomic context

    See SCL33 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    7
    Sequence:
    Chromosome: 1; NC_003070.9 (20629698..20633007)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Neighboring gene TBP-associated factor 7 Neighboring gene acyl-activating enzyme 18 Neighboring gene RNA polymerase II transcription mediator

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_001036118.4
    NM_001198307.2
    NM_001333699.1
    NM_001333700.1
    NM_001333702.1
    NM_104406.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing NAS
    Non-traceable Author Statement
    more info
    PubMed 
    acts_upstream_of_or_within mRNA splicing, via spliceosome IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    General protein information

    Preferred Names
    SC35-like splicing factor 33
    NP_001319238.1
    • SC35-like splicing factor 33 (SR33); FUNCTIONS IN: protein binding, RNA binding; INVOLVED IN: nuclear mRNA splicing, via spliceosome, RNA splicing; LOCATED IN: interchromatin granule, nuclear speck, nucleolus, plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: SC35-like splicing factor 30A (TAIR:AT3G13570.1); Has 74071 Blast hits to 42895 proteins in 2604 species: Archae - 973; Bacteria - 11117; Metazoa - 35835; Fungi - 6236; Plants - 4620; Viruses - 230; Other Eukaryotes - 15060 (source: NCBI BLink).
    NP_001319239.1
    • SC35-like splicing factor 33 (SR33); CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: SC35-like splicing factor 30A (TAIR:AT3G13570.1).
    NP_564685.4
    • SC35-like splicing factor 33 (SR33); FUNCTIONS IN: protein binding, RNA binding; INVOLVED IN: nuclear mRNA splicing, via spliceosome, RNA splicing; LOCATED IN: interchromatin granule, nuclear speck, nucleolus, plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: SC35-like splicing factor 30A (TAIR:AT3G13570.1); Has 74071 Blast hits to 42895 proteins in 2604 species: Archae - 973; Bacteria - 11117; Metazoa - 35835; Fungi - 6236; Plants - 4620; Viruses - 230; Other Eukaryotes - 15060 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      20629698..20633007
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001333701.1NP_001321067.1  SC35-like splicing factor 33 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W693, A0A1P8APR8
    2. NM_104406.6NP_564685.4  SC35-like splicing factor 33 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564685.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C0Z312, F4I090, F4I092, Q949P4, Q9C8A1, Q9SEU4
      UniProtKB/TrEMBL
      A0A654EK33
      Conserved Domains (2) summary
      COG0724
      Location:30117
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cl17169
      Location:36119
      RRM_SF; RNA recognition motif (RRM) superfamily
    3. NM_001333699.1NP_001319238.1  SC35-like splicing factor 33 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SEU4
    4. NM_001036118.4NP_001031195.4  SC35-like splicing factor 33 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031195.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SEU4
      Conserved Domains (2) summary
      COG0724
      Location:30117
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cl17169
      Location:36119
      RRM_SF; RNA recognition motif (RRM) superfamily
    5. NM_001333700.1NP_001319239.1  SC35-like splicing factor 33 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A2H1ZEE9, A0A654EK33
    6. NM_001198307.2NP_001185236.2  SC35-like splicing factor 33 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W6P9, A0A1P8APR4
    7. NM_001333702.1NP_001321066.1  SC35-like splicing factor 33 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W6P9, A0A1P8APR4