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    Tinf2 TERF1 interacting nuclear factor 2 [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101723913, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Tinf2
    Gene description
    TERF1 interacting nuclear factor 2
    Locus tag
    GW7_11953
    See related
    Ensembl:ENSHGLG00000003920
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Orthologs
    human mouse all
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    Genomic context

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    See Tinf2 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624820.1 (8262171..8265275)

    NW_004624820.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110345645 Neighboring gene Rab geranylgeranyltransferase subunit alpha Neighboring gene transglutaminase 1 Neighboring gene serine/threonine-protein kinase PAK 2 pseudogene Neighboring gene magnesium-dependent phosphatase 1 Neighboring gene charged multivesicular body protein 4A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624820 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables telomeric DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of telomere maintenance via telomere lengthening IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in telomere capping IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of shelterin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    TERF1-interacting nuclear factor 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624820.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      8262171..8265275
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004864097.3 → XP_004864154.1  TERF1-interacting nuclear factor 2 isoform X1

      UniProtKB/TrEMBL
      G5B281
      Conserved Domains (2) summary
      cd11741
      Location:247 → 350
      TIN2_TBM; TRF-binding motif region of TRF-Interacting Nuclear factor 2
      pfam14973
      Location:20 → 164
      TINF2_N; TERF1-interacting nuclear factor 2 N-terminus

    2. XM_013065262.2 → XP_012920716.1  TERF1-interacting nuclear factor 2 isoform X3

      UniProtKB/TrEMBL
      G5B281
      Conserved Domains (2) summary
      cd11741
      Location:183 → 286
      TIN2_TBM; TRF-binding motif region of TRF-Interacting Nuclear factor 2
      cl18929
      Location:1 → 100
      TIN2_N; N-terminal domain of TRF-interacting nuclear factor 2; shelterin complex protein of telomeres

    3. XM_004864098.3 → XP_004864155.1  TERF1-interacting nuclear factor 2 isoform X2

      UniProtKB/TrEMBL
      G5B281
      Related
      ENSHGLP00000005356.1, ENSHGLT00000005426.1
      Conserved Domains (2) summary
      cd11741
      Location:246 → 349
      TIN2_TBM; TRF-binding motif region of TRF-Interacting Nuclear factor 2
      pfam14973
      Location:20 → 163
      TINF2_N; TERF1-interacting nuclear factor 2 N-terminus
    Nucleotide Protein
    Heading Accession and Version

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