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    CRL1 NAD(P)-binding Rossmann-fold superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817925, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CRL1
    Official Full Name
    NAD(P)-binding Rossmann-fold superfamily protein
    Primary source
    TAIR:AT2G33590
    Locus tag
    AT2G33590
    See related
    Araport:AT2G33590
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtCRL1; CCR(Cinnamoyl coA:NADP oxidoreductase)-like 1; F4P9.36; F4P9_36
    Summary
    Encodes a protein with homology to members of the dihydroflavonol-4-reductase (DFR) superfamily. The expression pattern of AtCRL1 indicates that CRL1 has a role in embryogenesis and seed germination. AtCRL1 is induced by ABA, drought and heat, and is highly expressed in seeds.
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    Genomic context

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    See CRL1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Sequence:
    Chromosome: 2; NC_003071.7 (14224268..14226636)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Protein kinase superfamily protein Neighboring gene subtilisin-like protease Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene switch subunit 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cinnamoyl coA: NADP oxidoreductase-like 1 regulates abscisic acid response by modulating phaseic acid homeostasis in Arabidopsis thaliana. Yin X, et al. J Exp Bot, 2022 Jan 27. PMID 34718526
    2. Two differentially regulated Arabidopsis genes define a new branch of the DFR superfamily. Østergaard L, et al. Plant Sci, 2001 Feb 5. PMID 11166433
    3. Integrative Analysis from the Epigenome to Translatome Uncovers Patterns of Dominant Nuclear Regulation during Transient Stress. Lee TA, et al. Plant Cell, 2019 Nov. PMID 31519798, Free PMC Article
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Cinnamoyl coA: NADP oxidoreductase-like 1 regulates abscisic acid response by modulating phaseic acid homeostasis in Arabidopsis thaliana.
      Title: Cinnamoyl coA: NADP oxidoreductase-like 1 regulates abscisic acid response by modulating phaseic acid homeostasis in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_128919.4

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 
    acts_upstream_of_or_within response to abscisic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to heat IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water deprivation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    NAD(P)-binding Rossmann-fold superfamily protein
    NP_180917.1
    • NAD(P)-binding Rossmann-fold superfamily protein; FUNCTIONS IN: coenzyme binding, binding, cinnamoyl-CoA reductase activity, catalytic activity; INVOLVED IN: response to cadmium ion, lignin biosynthetic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: NAD-dependent epimerase/dehydratase (InterPro:IPR001509), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: NAD(P)-binding Rossmann-fold superfamily protein (TAIR:AT2G33600.1); Has 13062 Blast hits to 13044 proteins in 1974 species: Archae - 275; Bacteria - 5592; Metazoa - 467; Fungi - 894; Plants - 2514; Viruses - 60; Other Eukaryotes - 3260 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      14224268..14226636
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128919.4 → NP_180917.1  NAD(P)-binding Rossmann-fold superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180917.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VRE7, A0A7G2EF73, O22809
      Conserved Domains (1) summary
      cd08958
      Location:9 → 298
      FR_SDR_e; flavonoid reductase (FR), extended (e) SDRs
    Nucleotide Protein
    Heading Accession and Version

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