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    NAIP NLR family apoptosis inhibitory protein [ Otolemur garnettii (small-eared galago) ]

    Gene ID: 100954486, updated on 19-Jun-2024

    Summary

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    Gene symbol
    NAIP
    Gene description
    NLR family apoptosis inhibitory protein
    See related
    Ensembl:ENSOGAG00000026197
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Otolemur garnettii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes; Galagidae; Otolemur
    Orthologs
    human all
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    Genomic context

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    See NAIP in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    102 current OtoGar3 (GCF_000181295.1) Unplaced Scaffold NW_003852412.1 (5810531..5845246)

    NW_003852412.1Genomic Context describing neighboring genes Neighboring gene AP-2 complex subunit mu pseudogene Neighboring gene occludin Neighboring gene general transcription factor IIH subunit 2 Neighboring gene 5S ribosomal RNA Neighboring gene survival motor neuron protein-like Neighboring gene small EDRK-rich factor 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_003852412 Unplaced Scaffold Reference OtoGar3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in defense response to bacterium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in detection of bacterium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in pyroptotic inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of IPAF inflammasome complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    baculoviral IAP repeat-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Otolemur garnettii Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference OtoGar3

    Genomic

    1. NW_003852412.1 Reference OtoGar3

      Range
      5810531..5845246
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003785894.3 → XP_003785942.1  baculoviral IAP repeat-containing protein 1

      UniProtKB/TrEMBL
      H0XZQ1
      Related
      ENSOGAP00000021594.1, ENSOGAT00000025651.1
      Conserved Domains (7) summary
      smart00238
      Location:159 → 229
      BIR; Baculoviral inhibition of apoptosis protein repeat
      smart00382
      Location:463 → 600
      AAA; ATPases associated with a variety of cellular activities
      cd00022
      Location:279 → 347
      BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
      cd00116
      Location:1025 → 1276
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:1031 → 1054
      LRR_RI; leucine-rich repeat [structural motif]
      sd00034
      Location:1079 → 1100
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam05729
      Location:464 → 617
      NACHT; NACHT domain
    Nucleotide Protein
    Heading Accession and Version

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