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    cnga3a cyclic nucleotide gated channel subunit alpha 3a [ Oncorhynchus mykiss (rainbow trout) ]

    Gene ID: 101268918, updated on 12-May-2024

    Summary

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    Gene symbol
    cnga3a
    Gene description
    cyclic nucleotide gated channel subunit alpha 3a
    See related
    Ensembl:ENSOMYG00000002266
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Oncorhynchus mykiss
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Oncorhynchus
    Also known as
    cnga3
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    Genomic context

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    See cnga3a in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    101 current USDA_OmykA_1.1 (GCF_013265735.2) 5 NC_048569.1 (99114147..99133676, complement)
    100 previous assembly Omyk_1.0 (GCF_002163495.1) 5 NC_035081.1 (89247103..89264162)

    Chromosome 5 - NC_048569.1Genomic Context describing neighboring genes Neighboring gene gamma-aminobutyric acid receptor subunit alpha-5 Neighboring gene ubiquitin-protein ligase E3A Neighboring gene basic immunoglobulin-like variable motif-containing protein Neighboring gene uncharacterized LOC110523045

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cyclic nucleotide-gated channel α-3 (CNGA3) interacts with stereocilia tip-link cadherin 23 + exon 68 or alternatively with myosin VIIa, two proteins required for hair cell mechanotransduction. Selvakumar D, et al. J Biol Chem, 2013 Mar 8. PMID 23329832, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cGMP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables intracellularly cAMP-activated cation channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables intracellularly cGMP-activated cation channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein-containing complex binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in monoatomic cation transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of intracellular cyclic nucleotide activated cation channel complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cyclic nucleotide gated ion channel alpha 3 variant 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001281333.2 → NP_001268262.2  cyclic nucleotide gated ion channel alpha 3 variant 2

      Status: VALIDATED

      Source sequence(s)
      HQ542178, JAAXML020000005
      UniProtKB/TrEMBL
      G9BHI9
      Related
      ENSOMYP00000004324.2, ENSOMYT00000004844.2

    RefSeqs of Annotated Genomes: Oncorhynchus mykiss Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference USDA_OmykA_1.1 Primary Assembly

    Genomic

    1. NC_048569.1 Reference USDA_OmykA_1.1 Primary Assembly

      Range
      99114147..99133676 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036976518.1 → XP_036832413.1  cyclic nucleotide gated ion channel alpha 3 variant 2 isoform X2

      UniProtKB/TrEMBL
      A0A8C7M2E8
      Conserved Domains (3) summary
      cd00038
      Location:445 → 561
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
      pfam00520
      Location:131 → 373
      Ion_trans; Ion transport protein
      pfam16526
      Location:561 → 630
      CLZ; C-terminal leucine zipper domain of cyclic nucleotide-gated channels

    2. XM_036976517.1 → XP_036832412.1  cyclic nucleotide gated ion channel alpha 3 variant 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C7M2E8
      Conserved Domains (3) summary
      cd00038
      Location:463 → 579
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
      pfam00520
      Location:149 → 391
      Ion_trans; Ion transport protein
      pfam16526
      Location:579 → 648
      CLZ; C-terminal leucine zipper domain of cyclic nucleotide-gated channels
    Nucleotide Protein
    Heading Accession and Version

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