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    KRT10-AS1 KRT10 antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 147184, updated on 2-Nov-2024

    Summary

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    Official Symbol
    KRT10-AS1provided by HGNC
    Official Full Name
    KRT10 antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:28305
    See related
    Ensembl:ENSG00000167920 AllianceGenome:HGNC:28305
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    TMEM99
    Summary
    Predicted to be located in membrane. [provided by Alliance of Genome Resources, Nov 2024]
    Annotation information
    Note: Multiple studies indicate that this gene exhibits elevated expression in various types of cancers. [20 Feb 2019]
    Expression
    Biased expression in skin (RPKM 53.2), testis (RPKM 22.6) and 5 other tissues See more
    Orthologs
    all
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    Genomic context

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    See KRT10-AS1 in Genome Data Viewer
    Location:
    17q21.2
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (40819145..40836274)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (41683465..41700595)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (38975397..38992526)

    Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr17:38954190-38955389 Neighboring gene uncharacterized LOC105371776 Neighboring gene keratin 28 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr17:38975907-38977106 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr17:38983418-38984617 Neighboring gene keratin 10 Neighboring gene uncharacterized LOC105371777 Neighboring gene Sharpr-MPRA regulatory region 3631 Neighboring gene keratin 12 Neighboring gene keratin 20

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Evolution and cell-type specificity of human-specific genes preferentially expressed in progenitors of fetal neocortex. Florio M, et al. Elife, 2018 Mar 21. PMID 29561261, Free PMC Article
    2. Decoding the fine-scale structure of a breast cancer genome and transcriptome. Volik S, et al. Genome Res, 2006 Mar. PMID 16461635, Free PMC Article
    3. Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver. Xu XR, et al. Proc Natl Acad Sci U S A, 2001 Dec 18. PMID 11752456, Free PMC Article
    4. A germline-specific class of small RNAs binds mammalian Piwi proteins. Girard A, et al. Nature, 2006 Jul 13. PMID 16751776
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    General gene information

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    Markers

    Homology

    Other Names

    • transmembrane protein 99 (putative)

    Clone Names

    • MGC21518

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_160886.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC090283

    2. NR_160887.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC090283

    3. NR_160888.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC090283
      Related
      ENST00000301665.10

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

      Range
      40819145..40836274
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060941.1 Alternate T2T-CHM13v2.0

      Range
      41683465..41700595
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_033147.1: Suppressed sequence

      Description
      NG_033147.1: This RefSeq was removed because it is now thought that this gene does not encode a protein.

    2. NM_001195386.1: Suppressed sequence

      Description
      NM_001195386.1: This RefSeq was removed because it is now thought that this gene does not encode a protein.

    3. NM_001195387.1: Suppressed sequence

      Description
      NM_001195387.1: This RefSeq was removed because it is now thought that this gene does not encode a protein.

    4. NM_145274.3: Suppressed sequence

      Description
      NM_145274.3: This RefSeq was removed because it is now thought that this gene does not encode a protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8N816.2 GenPept UniProtKB/Swiss-Prot:Q8N816

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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