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    cht-5 Glycoside hydrolase family 19 catalytic domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179407, updated on 2-Nov-2024

    Summary

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    Official Symbol
    cht-5
    Official Full Name
    Glycoside hydrolase family 19 catalytic domain-containing protein
    Primary source
    WormBase:WBGene00007425
    Locus tag
    CELE_C08B6.4
    See related
    AllianceGenome:WB:WBGene00007425
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable chitinase activity. Predicted to be involved in cell wall macromolecule catabolic process and chitin catabolic process. Is expressed in amphid neurons and hypodermis. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See cht-5 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (10114629..10117413)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene DUF19 domain-containing protein;PIR Superfamily Protein Neighboring gene Uncharacterized protein Neighboring gene Glycosyltransferase family 92 protein Neighboring gene ncRNA Neighboring gene PBPe domain-containing protein Neighboring gene ncRNA Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Secretion of a novel developmentally regulated chitinase (family 19 glycosyl hydrolase) into the perivitelline fluid of the parasitic nematode, Ascaris suum. Geng J, et al. Mol Biochem Parasitol, 2002 Sep-Oct. PMID 12387846
    2. A spatiotemporal reconstruction of the C. elegans pharyngeal cuticle reveals a structure rich in phase-separating proteins. Kamal M, et al. Elife, 2022 Oct 19. PMID 36259463, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables chitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell wall macromolecule catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chitin catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Glycoside hydrolase family 19 catalytic domain-containing protein
    NP_001023635.1
    • Confirmed by transcript evidence
    NP_001366780.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      10114629..10117413
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001028464.3 → NP_001023635.1  Glycoside hydrolase family 19 catalytic domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001023635.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q65ZB0
      Conserved Domains (2) summary
      cd00325
      Location:101 → 398
      chitinase_glyco_hydro_19; Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some ...
      pfam00182
      Location:101 → 391
      Glyco_hydro_19; Chitinase class I

    2. NM_001380734.2 → NP_001366780.1  Glycoside hydrolase family 19 catalytic domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q17816
      Conserved Domains (1) summary
      cd00325
      Location:64 → 361
      chitinase_GH19; Glycoside hydrolase family 19, chitinase domain
    Nucleotide Protein
    Heading Accession and Version

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