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    ASH1L ASH1 like histone lysine methyltransferase [ Nomascus leucogenys (northern white-cheeked gibbon) ]

    Gene ID: 100580011, updated on 8-Mar-2024

    Summary

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    Gene symbol
    ASH1L
    Gene description
    ASH1 like histone lysine methyltransferase
    See related
    EnsemblRapid:ENSNLEG00000012163
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Nomascus leucogenys
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
    Orthologs
    human mouse all
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    Genomic context

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    See ASH1L in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    103 current Asia_NLE_v1 (GCF_006542625.1) 12 NC_044392.1 (45640142..45874895)
    102 previous assembly Nleu_3.0 (GCF_000146795.2) 12 NC_019827.1 (46605522..46838397)

    Chromosome 12 - NC_044392.1Genomic Context describing neighboring genes Neighboring gene claudin-6-like Neighboring gene U6 spliceosomal RNA Neighboring gene WAS/WASL-interacting protein family member 1-like Neighboring gene U6 spliceosomal RNA Neighboring gene small nucleolar RNA U13 Neighboring gene U6 spliceosomal RNA Neighboring gene putative uncharacterized protein RUSC1-AS1 Neighboring gene RUN and SH3 domain containing 1 Neighboring gene farnesyl diphosphate synthase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables chromatin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    histone-lysine N-methyltransferase ASH1L

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Asia_NLE_v1 Primary Assembly

    Genomic

    1. NC_044392.1 Reference Asia_NLE_v1 Primary Assembly

      Range
      45640142..45874895
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030824301.1 → XP_030680161.1  histone-lysine N-methyltransferase ASH1L isoform X1

      UniProtKB/TrEMBL
      G1RNF2
      Conserved Domains (5) summary
      cd05525
      Location:2438 → 2543
      Bromo_ASH1; Bromodomain; ASH1_like sub-family. ASH1 (absent, small, or homeotic 1) is a member of the trithorax-group in Drosophila melanogaster, an epigenetic transcriptional regulator of HOX genes. Drosophila ASH1 has been shown to methylate specific lysines in ...
      smart00570
      Location:2087 → 2138
      AWS; associated with SET domains
      cd04717
      Location:2660 → 2798
      BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...
      cd15548
      Location:2581 → 2623
      PHD_ASH1L; PHD finger found in histone-lysine N-methyltransferase ASH1L
      cd19174
      Location:2141 → 2281
      SET_ASH1L; SET domain (including post-SET domain) found in ASH1-like protein (ASH1L) and similar proteins

    2. XM_030824299.1 → XP_030680159.1  histone-lysine N-methyltransferase ASH1L isoform X1

      UniProtKB/TrEMBL
      G1RNF2

    3. XM_030824300.1 → XP_030680160.1  histone-lysine N-methyltransferase ASH1L isoform X1

      UniProtKB/TrEMBL
      G1RNF2
      Conserved Domains (5) summary
      cd05525
      Location:2438 → 2543
      Bromo_ASH1; Bromodomain; ASH1_like sub-family. ASH1 (absent, small, or homeotic 1) is a member of the trithorax-group in Drosophila melanogaster, an epigenetic transcriptional regulator of HOX genes. Drosophila ASH1 has been shown to methylate specific lysines in ...
      smart00570
      Location:2087 → 2138
      AWS; associated with SET domains
      cd04717
      Location:2660 → 2798
      BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...
      cd15548
      Location:2581 → 2623
      PHD_ASH1L; PHD finger found in histone-lysine N-methyltransferase ASH1L
      cd19174
      Location:2141 → 2281
      SET_ASH1L; SET domain (including post-SET domain) found in ASH1-like protein (ASH1L) and similar proteins

    4. XM_030824302.1 → XP_030680162.1  histone-lysine N-methyltransferase ASH1L isoform X2

      UniProtKB/TrEMBL
      G1RNF2
      Related
      ENSNLEP00000014766.4, ENSNLET00000015510.4
      Conserved Domains (5) summary
      cd05525
      Location:2438 → 2543
      Bromo_ASH1; Bromodomain; ASH1_like sub-family. ASH1 (absent, small, or homeotic 1) is a member of the trithorax-group in Drosophila melanogaster, an epigenetic transcriptional regulator of HOX genes. Drosophila ASH1 has been shown to methylate specific lysines in ...
      smart00570
      Location:2087 → 2138
      AWS; associated with SET domains
      cd04717
      Location:2660 → 2794
      BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...
      cd15548
      Location:2581 → 2623
      PHD_ASH1L; PHD finger found in histone-lysine N-methyltransferase ASH1L
      cd19174
      Location:2141 → 2281
      SET_ASH1L; SET domain (including post-SET domain) found in ASH1-like protein (ASH1L) and similar proteins

    5. XM_030824303.1 → XP_030680163.1  histone-lysine N-methyltransferase ASH1L isoform X3

      UniProtKB/TrEMBL
      G1RNF2
      Related
      ENSNLEP00000048443.2, ENSNLET00000053748.2
      Conserved Domains (5) summary
      cd05525
      Location:2378 → 2483
      Bromo_ASH1; Bromodomain; ASH1_like sub-family. ASH1 (absent, small, or homeotic 1) is a member of the trithorax-group in Drosophila melanogaster, an epigenetic transcriptional regulator of HOX genes. Drosophila ASH1 has been shown to methylate specific lysines in ...
      smart00570
      Location:2027 → 2078
      AWS; associated with SET domains
      cd04717
      Location:2600 → 2738
      BAH_polybromo; BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional ...
      cd15548
      Location:2521 → 2563
      PHD_ASH1L; PHD finger found in histone-lysine N-methyltransferase ASH1L
      cd19174
      Location:2081 → 2221
      SET_ASH1L; SET domain (including post-SET domain) found in ASH1-like protein (ASH1L) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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