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    Pdk1 pyruvate dehydrogenase kinase 1 [ Rattus rattus (black rat) ]

    Gene ID: 116901510, updated on 18-Mar-2024

    Summary

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    Gene symbol
    Pdk1
    Gene description
    pyruvate dehydrogenase kinase 1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus rattus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Orthologs
    human mouse all
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    Genomic context

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    See Pdk1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    100 current Rrattus_CSIRO_v1 (GCF_011064425.1) 5 NC_046158.1 (49170502..49199496)

    Chromosome 5 - NC_046158.1Genomic Context describing neighboring genes Neighboring gene 28S ribosomal protein S36, mitochondrial-like Neighboring gene integrin subunit alpha 6 Neighboring gene small nucleolar RNA SNORA42/SNORA80 family Neighboring gene small nucleolar RNA SNORA17 Neighboring gene Rap guanine nucleotide exchange factor 4 Neighboring gene small nucleolar RNA SNORA42/SNORA80 family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_046158.1 Chromosome 5 Reference Rrattus_CSIRO_v1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables pyruvate dehydrogenase (acetyl-transferring) kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of glucose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Rattus rattus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rrattus_CSIRO_v1 Primary Assembly

    Genomic

    1. NC_046158.1 Reference Rrattus_CSIRO_v1 Primary Assembly

      Range
      49170502..49199496
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_032903481.1 → XP_032759372.1  pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X1

      Conserved Domains (2) summary
      cd16929
      Location:222 → 388
      HATPase_PDK-like; Histidine kinase-like ATPase domain of pyruvate dehydrogenase kinase, branched-chain alpha-ketoacid dehydrogenase kinase and related domains
      pfam10436
      Location:56 → 218
      BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase

    2. XM_032903482.1 → XP_032759373.1  pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X2

      Conserved Domains (2) summary
      cd16929
      Location:146 → 312
      HATPase_PDK-like; Histidine kinase-like ATPase domain of pyruvate dehydrogenase kinase, branched-chain alpha-ketoacid dehydrogenase kinase and related domains
      pfam10436
      Location:2 → 142
      BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase

    RNA

    1. XR_004388004.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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