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    RPI2 ribose-5-phosphate isomerase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 814657, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RPI2
    Official Full Name
    ribose-5-phosphate isomerase 2
    Primary source
    TAIR:AT2G01290
    Locus tag
    AT2G01290
    See related
    Araport:AT2G01290
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F10A8.17; F10A8_17; ribose-5-phosphate isomerase 2
    Summary
    Cytosolic ribose-5-phosphate isomerase. Knockout mutation causes chloroplast dysfunction, late flowering and premature cell death.
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    Genomic context

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    See RPI2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    1
    Sequence:
    Chromosome: 2; NC_003071.7 (148919..150585, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene quiescin-sulfhydryl oxidase 2 Neighboring gene RING/FYVE/PHD zinc finger superfamily protein Neighboring gene miscRNA Neighboring gene Cyclin/Brf1-like TBP-binding protein Neighboring gene ncRNA Neighboring gene mediator of RNA polymerase II transcription subunit Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Deficiency in a cytosolic ribose-5-phosphate isomerase causes chloroplast dysfunction, late flowering and premature cell death in Arabidopsis. Xiong Y, et al. Physiol Plant, 2009 Nov. PMID 19744161
    2. A mutation in an Arabidopsis ribose 5-phosphate isomerase reduces cellulose synthesis and is rescued by exogenous uridine. Howles PA, et al. Plant J, 2006 Nov. PMID 17059404
    3. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Mutation in the non-oxidative phase of RPI2 leads to premature cell death and altered morphology in Arabidopsis plants.
      Title: Deficiency in a cytosolic ribose-5-phosphate isomerase causes chloroplast dysfunction, late flowering and premature cell death in Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_126190.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ribose-5-phosphate isomerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in pentose-phosphate shunt, non-oxidative branch IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within vegetative to reproductive phase transition of meristem IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ribose-5-phosphate isomerase 2
    NP_178238.1
    • ribose-5-phosphate isomerase 2 (RPI2); CONTAINS InterPro DOMAIN/s: Ribose-5-phosphate isomerase, type A, subgroup (InterPro:IPR020672), Ribose 5-phosphate isomerase, type A (InterPro:IPR004788); BEST Arabidopsis thaliana protein match is: Ribose 5-phosphate isomerase, type A protein (TAIR:AT1G71100.1); Has 5035 Blast hits to 5035 proteins in 1937 species: Archae - 235; Bacteria - 3542; Metazoa - 112; Fungi - 145; Plants - 141; Viruses - 0; Other Eukaryotes - 860 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      148919..150585 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_126190.1 → NP_178238.1  ribose-5-phosphate isomerase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178238.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q1PFB3, Q9ZU38
      UniProtKB/TrEMBL
      A0A178W072, A0A5S9WWA0
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZU38.1

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