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    LOC118663754 centrosomal protein of 76 kDa [ Myotis myotis ]

    Gene ID: 118663754, updated on 30-Mar-2024

    Summary

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    Gene symbol
    LOC118663754
    Gene description
    centrosomal protein of 76 kDa
    Locus tag
    mMyoMyo1_002679
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Myotis myotis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Myotis
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    Genomic context

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    See LOC118663754 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    100 current mMyoMyo1.p (GCF_014108235.1) Unplaced Scaffold NW_023416401.1 (30694036..30843527)

    NW_023416401.1Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase non-receptor type 2 Neighboring gene proteasome assembly chaperone 2 Neighboring gene 40S ribosomal protein S2-like Neighboring gene PRELI domain containing 3A Neighboring gene AFG3 like matrix AAA peptidase subunit 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_023416401 Unplaced Scaffold Reference mMyoMyo1.p Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Golgi vesicle transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actin filament network formation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actin filament polymerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actin nucleation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cleavage furrow formation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in establishment of meiotic spindle localization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in polar body extrusion after meiotic divisions IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell cortex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasmic vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    centrosomal protein of 76 kDa; protein spire homolog 1; uncharacterized protein LOC118663754
    Names
    centrosomal protein 76
    spire type actin nucleation factor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Myotis myotis Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mMyoMyo1.p Primary Assembly

    Genomic

    1. NW_023416401.1 Reference mMyoMyo1.p Primary Assembly

      Range
      30694036..30843527
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036323694.1 → XP_036179587.1  centrosomal protein of 76 kDa isoform X14

      UniProtKB/TrEMBL
      A0A7J7VX20
      Conserved Domains (1) summary
      pfam15627
      Location:101 → 260
      CEP76-C2; CEP76 C2 domain

    2. XM_036323683.1 → XP_036179576.1  uncharacterized protein LOC118663754 isoform X4

      Conserved Domains (7) summary
      cd15767
      Location:1189 → 1309
      FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins
      pfam15627
      Location:101 → 260
      CEP76-C2; CEP76 C2 domain
      cd22065
      Location:803 → 834
      WH2_Spire_1-2_r1; first tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cd22078
      Location:843 → 874
      WH2_Spire1_r2-like; second tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1 (Spir1), and related proteins
      cd22080
      Location:908 → 931
      WH2_Spire1_r4; fourth tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1
      cd22186
      Location:877 → 899
      WH2_Spire1-2_r3; third tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cl21453
      Location:606 → 779
      PKc_like; Protein Kinases, catalytic domain

    3. XM_036323688.1 → XP_036179581.1  uncharacterized protein LOC118663754 isoform X8

      Conserved Domains (6) summary
      cd15767
      Location:1114 → 1234
      FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins
      pfam15627
      Location:146 → 305
      CEP76-C2; CEP76 C2 domain
      cd22065
      Location:728 → 759
      WH2_Spire_1-2_r1; first tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cd22078
      Location:768 → 799
      WH2_Spire1_r2-like; second tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1 (Spir1), and related proteins
      cd22080
      Location:833 → 856
      WH2_Spire1_r4; fourth tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1
      cd22186
      Location:802 → 824
      WH2_Spire1-2_r3; third tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2

    4. XM_036323691.1 → XP_036179584.1  centrosomal protein of 76 kDa isoform X11

      Conserved Domains (6) summary
      pfam15627
      Location:146 → 305
      CEP76-C2; CEP76 C2 domain
      cd22065
      Location:848 → 879
      WH2_Spire_1-2_r1; first tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cd22078
      Location:888 → 919
      WH2_Spire1_r2-like; second tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1 (Spir1), and related proteins
      cd22080
      Location:953 → 976
      WH2_Spire1_r4; fourth tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1
      cd22186
      Location:922 → 944
      WH2_Spire1-2_r3; third tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cl21453
      Location:651 → 824
      PKc_like; Protein Kinases, catalytic domain

    5. XM_036323689.1 → XP_036179582.1  centrosomal protein of 76 kDa isoform X9

      Conserved Domains (6) summary
      pfam15627
      Location:146 → 305
      CEP76-C2; CEP76 C2 domain
      cd22065
      Location:848 → 879
      WH2_Spire_1-2_r1; first tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cd22078
      Location:888 → 919
      WH2_Spire1_r2-like; second tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1 (Spir1), and related proteins
      cd22080
      Location:953 → 976
      WH2_Spire1_r4; fourth tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1
      cd22186
      Location:922 → 944
      WH2_Spire1-2_r3; third tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cl21453
      Location:651 → 824
      PKc_like; Protein Kinases, catalytic domain

    6. XM_036323680.1 → XP_036179573.1  uncharacterized protein LOC118663754 isoform X1

      Conserved Domains (7) summary
      cd15767
      Location:1234 → 1354
      FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins
      pfam15627
      Location:146 → 305
      CEP76-C2; CEP76 C2 domain
      cd22065
      Location:848 → 879
      WH2_Spire_1-2_r1; first tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cd22078
      Location:888 → 919
      WH2_Spire1_r2-like; second tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1 (Spir1), and related proteins
      cd22080
      Location:953 → 976
      WH2_Spire1_r4; fourth tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1
      cd22186
      Location:922 → 944
      WH2_Spire1-2_r3; third tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cl21453
      Location:651 → 824
      PKc_like; Protein Kinases, catalytic domain

    7. XM_036323681.1 → XP_036179574.1  uncharacterized protein LOC118663754 isoform X2

      Conserved Domains (7) summary
      cd15767
      Location:1233 → 1353
      FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins
      pfam15627
      Location:146 → 305
      CEP76-C2; CEP76 C2 domain
      cd22065
      Location:848 → 879
      WH2_Spire_1-2_r1; first tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cd22078
      Location:888 → 919
      WH2_Spire1_r2-like; second tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1 (Spir1), and related proteins
      cd22080
      Location:953 → 976
      WH2_Spire1_r4; fourth tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1
      cd22186
      Location:922 → 944
      WH2_Spire1-2_r3; third tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cl21453
      Location:651 → 824
      PKc_like; Protein Kinases, catalytic domain

    8. XM_036323686.1 → XP_036179579.1  uncharacterized protein LOC118663754 isoform X7

      Conserved Domains (7) summary
      cd15767
      Location:1135 → 1250
      FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins
      pfam15627
      Location:146 → 305
      CEP76-C2; CEP76 C2 domain
      cd22065
      Location:848 → 879
      WH2_Spire_1-2_r1; first tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cd22078
      Location:888 → 919
      WH2_Spire1_r2-like; second tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1 (Spir1), and related proteins
      cd22080
      Location:953 → 976
      WH2_Spire1_r4; fourth tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1
      cd22186
      Location:922 → 944
      WH2_Spire1-2_r3; third tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cl21453
      Location:651 → 824
      PKc_like; Protein Kinases, catalytic domain

    9. XM_036323684.1 → XP_036179577.1  uncharacterized protein LOC118663754 isoform X5

      Conserved Domains (7) summary
      cd15767
      Location:1176 → 1296
      FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins
      pfam15627
      Location:146 → 305
      CEP76-C2; CEP76 C2 domain
      cd22065
      Location:848 → 879
      WH2_Spire_1-2_r1; first tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cd22078
      Location:888 → 919
      WH2_Spire1_r2-like; second tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1 (Spir1), and related proteins
      cd22080
      Location:953 → 976
      WH2_Spire1_r4; fourth tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1
      cd22186
      Location:922 → 944
      WH2_Spire1-2_r3; third tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cl21453
      Location:651 → 824
      PKc_like; Protein Kinases, catalytic domain

    10. XM_036323682.1 → XP_036179575.1  uncharacterized protein LOC118663754 isoform X3

      Conserved Domains (7) summary
      cd15767
      Location:1220 → 1340
      FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins
      pfam15627
      Location:146 → 305
      CEP76-C2; CEP76 C2 domain
      cd22065
      Location:848 → 879
      WH2_Spire_1-2_r1; first tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cd22078
      Location:888 → 919
      WH2_Spire1_r2-like; second tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1 (Spir1), and related proteins
      cd22080
      Location:953 → 976
      WH2_Spire1_r4; fourth tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1
      cd22186
      Location:922 → 944
      WH2_Spire1-2_r3; third tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cl21453
      Location:651 → 824
      PKc_like; Protein Kinases, catalytic domain

    11. XM_036323690.1 → XP_036179583.1  protein spire homolog 1 isoform X10

      Conserved Domains (6) summary
      cd15767
      Location:972 → 1092
      FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins
      cd22065
      Location:586 → 617
      WH2_Spire_1-2_r1; first tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cd22078
      Location:626 → 657
      WH2_Spire1_r2-like; second tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1 (Spir1), and related proteins
      cd22080
      Location:691 → 714
      WH2_Spire1_r4; fourth tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1
      cd22186
      Location:660 → 682
      WH2_Spire1-2_r3; third tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cl21453
      Location:389 → 562
      PKc_like; Protein Kinases, catalytic domain

    12. XM_036323685.1 → XP_036179578.1  uncharacterized protein LOC118663754 isoform X6

      Conserved Domains (7) summary
      cd15767
      Location:1162 → 1282
      FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins
      pfam15627
      Location:146 → 305
      CEP76-C2; CEP76 C2 domain
      cd22065
      Location:848 → 879
      WH2_Spire_1-2_r1; first tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cd22078
      Location:888 → 919
      WH2_Spire1_r2-like; second tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1 (Spir1), and related proteins
      cd22080
      Location:953 → 976
      WH2_Spire1_r4; fourth tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1
      cd22186
      Location:922 → 944
      WH2_Spire1-2_r3; third tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cl21453
      Location:651 → 824
      PKc_like; Protein Kinases, catalytic domain

    13. XM_036323692.1 → XP_036179585.1  protein spire homolog 1 isoform X12

      UniProtKB/TrEMBL
      A0A7J7W0X7
      Conserved Domains (6) summary
      cd15767
      Location:587 → 707
      FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins
      pfam16474
      Location:39 → 235
      KIND; Kinase non-catalytic C-lobe domain
      cd22065
      Location:259 → 290
      WH2_Spire_1-2_r1; first tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cd22078
      Location:299 → 330
      WH2_Spire1_r2-like; second tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1 (Spir1), and related proteins
      cd22080
      Location:364 → 387
      WH2_Spire1_r4; fourth tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1
      cd22186
      Location:333 → 355
      WH2_Spire1-2_r3; third tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2

    14. XM_036323693.1 → XP_036179586.1  protein spire homolog 1 isoform X13

      UniProtKB/TrEMBL
      A0A7J7W0X7, A0A7J7W1F4
      Conserved Domains (6) summary
      cd15767
      Location:573 → 693
      FYVE_SPIR1; FYVE-related domain found in protein spire homolog 1 (Spire1) and similar proteins
      pfam16474
      Location:39 → 235
      KIND; Kinase non-catalytic C-lobe domain
      cd22065
      Location:259 → 290
      WH2_Spire_1-2_r1; first tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
      cd22078
      Location:299 → 330
      WH2_Spire1_r2-like; second tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1 (Spir1), and related proteins
      cd22080
      Location:364 → 387
      WH2_Spire1_r4; fourth tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homolog 1
      cd22186
      Location:333 → 355
      WH2_Spire1-2_r3; third tandem Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif) repeat of protein Spire homologs 1 and 2
    Nucleotide Protein
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