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    PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 [ Homo sapiens (human) ]

    Gene ID: 9677, updated on 2-Nov-2024

    Summary

    Official Symbol
    PPIP5K1provided by HGNC
    Official Full Name
    diphosphoinositol pentakisphosphate kinase 1provided by HGNC
    Primary source
    HGNC:HGNC:29023
    See related
    Ensembl:ENSG00000168781 MIM:610979; AllianceGenome:HGNC:29023
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    IP6K; IPS1; VIP1; hsVIP1; HISPPD2A
    Summary
    This gene encodes a dual functional inositol kinase. The encoded enzyme converts inositol hexakisphosphate to diphosphoinositol pentakisphosphate and diphosphoinositol pentakisphosphate to bis-diphosphoinositol tetrakisphosphate. This protein may be important for intracellular signaling pathways. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 15.[provided by RefSeq, Jun 2010]
    Expression
    Ubiquitous expression in duodenum (RPKM 8.8), small intestine (RPKM 8.2) and 25 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See PPIP5K1 in Genome Data Viewer
    Location:
    15q15.3
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (43533475..43590253, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (41340826..41397612, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (43825673..43882451, complement)

    Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene tubulin gamma complex component 4 Neighboring gene tumor protein p53 binding protein 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:43734212-43734815 Neighboring gene ReSE screen-validated silencer GRCh37_chr15:43769402-43769643 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr15:43784380-43785088 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr15:43785089-43785795 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:43787292-43787792 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9314 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6386 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9315 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:43810281-43810924 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:43819912-43820544 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:43821526-43822026 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:43822027-43822527 Neighboring gene microtubule associated protein 1A Neighboring gene RNA, U6 small nuclear 554, pseudogene Neighboring gene creatine kinase, mitochondrial 1B Neighboring gene stereocilin

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    EBI GWAS Catalog

    Description
    A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.
    EBI GWAS Catalog

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • KIAA0377, MGC51871, DKFZp313L0221

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    involved_in inositol metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in inositol metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in inositol phosphate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in inositol phosphate metabolic process TAS
    Traceable Author Statement
    more info
     
    involved_in phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
     

    General protein information

    Preferred Names
    inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
    Names
    IP6 kinase
    VIP1 homolog
    histidine acid phosphatase domain containing 2A
    histidine acid phosphatase domain-containing protein 2A
    inositol pyrophosphate synthase 1
    insP6 and PP-IP5 kinase 1
    NP_001124330.1
    NP_001124331.1
    NP_001177143.1
    NP_001341311.1
    NP_001341312.1
    NP_001341313.1
    NP_001341314.1
    NP_001341315.1
    NP_001341316.1
    NP_001341317.1
    NP_001341318.1
    NP_001341319.1
    NP_001341320.1
    NP_001341321.1
    NP_001341322.1
    NP_001341323.1
    NP_001341324.1
    NP_001341325.1
    NP_001341326.1
    NP_001341327.1
    NP_001341328.1
    NP_001341329.1
    NP_001341330.1
    NP_001341331.1
    NP_001380898.1
    NP_001380899.1
    NP_001380900.1
    NP_001381324.1
    NP_055474.3
    XP_005254861.1
    XP_006720849.1
    XP_011520551.1
    XP_011520552.1
    XP_011520554.1
    XP_011520556.1
    XP_011520560.1
    XP_016878225.1
    XP_016878226.1
    XP_016878236.1
    XP_016878242.1
    XP_016878243.1
    XP_047289332.1
    XP_047289333.1
    XP_047289334.1
    XP_047289335.1
    XP_047289336.1
    XP_047289337.1
    XP_047289338.1
    XP_047289339.1
    XP_047289340.1
    XP_047289341.1
    XP_047289342.1
    XP_047289343.1
    XP_047289344.1
    XP_047289345.1
    XP_047289346.1
    XP_054235239.1
    XP_054235240.1
    XP_054235241.1
    XP_054235242.1
    XP_054235243.1
    XP_054235244.1
    XP_054235245.1
    XP_054235246.1
    XP_054235247.1
    XP_054235248.1
    XP_054235249.1
    XP_054235250.1
    XP_054235251.1
    XP_054235252.1
    XP_054235253.1
    XP_054235254.1
    XP_054235255.1
    XP_054235256.1
    XP_054235257.1
    XP_054235258.1
    XP_054235259.1
    XP_054235260.1
    XP_054235261.1
    XP_054235262.1
    XP_054235263.1
    XP_054235264.1
    XP_054235265.1
    XP_054235266.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_022929.1 RefSeqGene

      Range
      5046..61779
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001130858.4NP_001124330.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 5

      See identical proteins and their annotated locations for NP_001124330.1

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      Consensus CDS
      CCDS45252.1
      UniProtKB/Swiss-Prot
      O15082, Q5HYF8, Q6PFW1, Q7Z3A7, Q86TE7, Q86UV3, Q86UV4, Q86XW8, Q8IZN0
      UniProtKB/TrEMBL
      F8W9A8
      Related
      ENSP00000380129.2, ENST00000396923.7
      Conserved Domains (1) summary
      pfam00328
      Location:390910
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    2. NM_001130859.3NP_001124331.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 2

      See identical proteins and their annotated locations for NP_001124331.1

      Status: REVIEWED

      Source sequence(s)
      AC011330, BC057395, BX538022, DB065605
      Consensus CDS
      CCDS32215.1
      UniProtKB/TrEMBL
      F8W9A8
      Related
      ENSP00000334779.4, ENST00000334933.8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    3. NM_001190214.2NP_001177143.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 6

      See identical proteins and their annotated locations for NP_001177143.1

      Status: REVIEWED

      Source sequence(s)
      AB002375, AC011330, AC019011, AI638651, DB065605
      Consensus CDS
      CCDS53937.1
      UniProtKB/TrEMBL
      F8W9A8
      Related
      ENSP00000353253.4, ENST00000360135.8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    4. NM_001354382.3NP_001341311.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 7

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      Consensus CDS
      CCDS86452.1
      UniProtKB/TrEMBL
      B7WPL9, F8W9A8
      Related
      ENSP00000371309.1, ENST00000381885.5
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    5. NM_001354383.2NP_001341312.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 7

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      Consensus CDS
      CCDS86452.1
      UniProtKB/TrEMBL
      B7WPL9, F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    6. NM_001354384.2NP_001341313.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 7

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      Consensus CDS
      CCDS86452.1
      UniProtKB/TrEMBL
      B7WPL9, F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    7. NM_001354385.2NP_001341314.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 7

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      Consensus CDS
      CCDS86452.1
      UniProtKB/TrEMBL
      B7WPL9, F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    8. NM_001354386.2NP_001341315.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 7

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      Consensus CDS
      CCDS86452.1
      UniProtKB/TrEMBL
      B7WPL9, F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    9. NM_001354387.2NP_001341316.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 8

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390898
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    10. NM_001354388.2NP_001341317.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 8

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390898
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    11. NM_001354389.2NP_001341318.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 8

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390898
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    12. NM_001354390.2NP_001341319.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      Consensus CDS
      CCDS32215.1
      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    13. NM_001354391.2NP_001341320.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      Consensus CDS
      CCDS32215.1
      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    14. NM_001354392.2NP_001341321.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      Consensus CDS
      CCDS32215.1
      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    15. NM_001354393.2NP_001341322.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 9

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390898
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    16. NM_001354394.2NP_001341323.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 10

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390878
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    17. NM_001354395.2NP_001341324.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 11

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    18. NM_001354396.2NP_001341325.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 11

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    19. NM_001354397.2NP_001341326.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 11

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    20. NM_001354398.2NP_001341327.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 12

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:135651
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    21. NM_001354399.2NP_001341328.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 12

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:135651
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    22. NM_001354400.2NP_001341329.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 12

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:135651
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    23. NM_001354401.2NP_001341330.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 13

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      Conserved Domains (2) summary
      cl11399
      Location:5242
      HP; Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction
      cl27087
      Location:547654
      SPOR; Sporulation related domain
    24. NM_001354402.2NP_001341331.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 14

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      Conserved Domains (2) summary
      cl11399
      Location:5234
      HP; Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction
      cl27087
      Location:518625
      SPOR; Sporulation related domain
    25. NM_001393969.1NP_001380898.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 15

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      UniProtKB/TrEMBL
      A0A9L9PYJ9, F8W9A8
      Conserved Domains (2) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
      pfam18086
      Location:55144
      PPIP5K2_N; Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain
    26. NM_001393970.1NP_001380899.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 15

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      UniProtKB/TrEMBL
      A0A9L9PYJ9, F8W9A8
      Related
      ENSP00000516724.1, ENST00000707073.1
      Conserved Domains (2) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
      pfam18086
      Location:55144
      PPIP5K2_N; Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain
    27. NM_001393971.1NP_001380900.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 16

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      cd07061
      Location:525894
      HP_HAP_like; Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction
    28. NM_001394395.1NP_001381324.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 17

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      Consensus CDS
      CCDS91989.1
      UniProtKB/TrEMBL
      A0A8J8ZH50, F8W9A8
      Related
      ENSP00000400887.2, ENST00000420765.6
      Conserved Domains (1) summary
      cd07061
      Location:525902
      HP_HAP_like; Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction
    29. NM_014659.6NP_055474.3  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 2

      See identical proteins and their annotated locations for NP_055474.3

      Status: REVIEWED

      Source sequence(s)
      AC011330, AC019011
      Consensus CDS
      CCDS32215.1
      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

      Range
      43533475..43590253 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047433387.1XP_047289343.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X8

    2. XM_047433384.1XP_047289340.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X5

    3. XM_047433381.1XP_047289337.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X4

      UniProtKB/TrEMBL
      B7WPL9
      Related
      ENSP00000371303.4, ENST00000381879.8
    4. XM_047433380.1XP_047289336.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X3

      UniProtKB/TrEMBL
      A0A9L9PYJ9
    5. XM_011522254.2XP_011520556.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1

      See identical proteins and their annotated locations for XP_011520556.1

      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    6. XM_047433377.1XP_047289333.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1

    7. XM_017022753.2XP_016878242.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X8

      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390898
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    8. XM_011522252.2XP_011520554.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1

      See identical proteins and their annotated locations for XP_011520554.1

      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    9. XM_047433390.1XP_047289346.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X10

    10. XM_047433379.1XP_047289335.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X2

    11. XM_006720786.3XP_006720849.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X9

      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    12. XM_005254804.1XP_005254861.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X7

      See identical proteins and their annotated locations for XP_005254861.1

      UniProtKB/TrEMBL
      F8W9A8
      Related
      ENSP00000353446.4, ENST00000360301.8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    13. XM_011522249.1XP_011520551.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1

      See identical proteins and their annotated locations for XP_011520551.1

      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    14. XM_047433389.1XP_047289345.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X9

    15. XM_047433382.1XP_047289338.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X4

      UniProtKB/TrEMBL
      B7WPL9
    16. XM_047433386.1XP_047289342.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X8

    17. XM_047433383.1XP_047289339.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X5

    18. XM_017022754.2XP_016878243.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X9

      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    19. XM_047433385.1XP_047289341.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X7

    20. XM_047433376.1XP_047289332.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1

    21. XM_017022737.2XP_016878226.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1

      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    22. XM_047433388.1XP_047289344.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X9

    23. XM_011522250.2XP_011520552.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1

      See identical proteins and their annotated locations for XP_011520552.1

      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    24. XM_017022736.2XP_016878225.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1

      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    25. XM_047433378.1XP_047289334.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1

    26. XM_017022747.2XP_016878236.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X6

      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:390906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    27. XM_011522258.2XP_011520560.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X11

      UniProtKB/TrEMBL
      F8W9A8
      Conserved Domains (1) summary
      pfam00328
      Location:135651
      His_Phos_2; Histidine phosphatase superfamily (branch 2)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060939.1 Alternate T2T-CHM13v2.0

      Range
      41340826..41397612 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054379284.1XP_054235259.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X8

    2. XM_054379278.1XP_054235253.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X5

    3. XM_054379275.1XP_054235250.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X4

      UniProtKB/TrEMBL
      B7WPL9
    4. XM_054379274.1XP_054235249.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X3

      UniProtKB/TrEMBL
      A0A9L9PYJ9
    5. XM_054379268.1XP_054235243.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1

    6. XM_054379270.1XP_054235245.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1

    7. XM_054379283.1XP_054235258.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X8

    8. XM_054379266.1XP_054235241.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1

    9. XM_054379289.1XP_054235264.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X10

    10. XM_054379273.1XP_054235248.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X2

    11. XM_054379285.1XP_054235260.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X9

    12. XM_054379280.1XP_054235255.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X7

    13. XM_054379264.1XP_054235239.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1

    14. XM_054379288.1XP_054235263.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X9

    15. XM_054379276.1XP_054235251.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X4

      UniProtKB/TrEMBL
      B7WPL9
    16. XM_054379282.1XP_054235257.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X8

    17. XM_054379277.1XP_054235252.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X5

    18. XM_054379287.1XP_054235262.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X9

    19. XM_054379281.1XP_054235256.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X7

    20. XM_054379265.1XP_054235240.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1

    21. XM_054379267.1XP_054235242.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1

    22. XM_054379286.1XP_054235261.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X9

    23. XM_054379271.1XP_054235246.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1

    24. XM_054379269.1XP_054235244.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1

    25. XM_054379272.1XP_054235247.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1

    26. XM_054379279.1XP_054235254.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X6

    27. XM_054379290.1XP_054235265.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X11

    28. XM_054379291.1XP_054235266.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X12

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001024463.3: Suppressed sequence

      Description
      NM_001024463.3: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript, which aligns to the reference genome with non-consensus splice sites.