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    MAP3K7 mitogen-activated protein kinase kinase kinase 7 [ Varanus komodoensis (Komodo dragon) ]

    Gene ID: 123022147, updated on 22-Mar-2024

    Summary

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    Gene symbol
    MAP3K7
    Gene description
    mitogen-activated protein kinase kinase kinase 7
    Locus tag
    EYD10_00729
    See related
    Ensembl:ENSVKKG00000008928
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Varanus komodoensis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Anguimorpha; Paleoanguimorpha; Varanoidea; Varanidae; Varanus
    Orthologs
    human mouse all
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    Genomic context

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    See MAP3K7 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    100 current ASM479886v1 (GCF_004798865.1) Unplaced Scaffold NW_025335268.1 (66708604..66754960)

    NW_025335268.1Genomic Context describing neighboring genes Neighboring gene transfer RNA serine (anticodon GCU) Neighboring gene 5S ribosomal RNA Neighboring gene BTB domain and CNC homolog 2 Neighboring gene gap junction protein alpha 10

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_025335268 Unplaced Scaffold Reference ASM479886v1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables MAP kinase kinase kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in JNK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitogen-activated protein kinase kinase kinase 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Varanus komodoensis Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM479886v1

    Genomic

    1. NW_025335268.1 Reference ASM479886v1

      Range
      66708604..66754960
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_044427618.1 → XP_044283553.1  mitogen-activated protein kinase kinase kinase 7 isoform X4

      Conserved Domains (1) summary
      cd14058
      Location:4 → 254
      STKc_TAK1; Catalytic domain of the Serine/Threonine Kinase, Transforming Growth Factor beta Activated Kinase-1

    2. XM_044427602.1 → XP_044283537.1  mitogen-activated protein kinase kinase kinase 7 isoform X2

      Conserved Domains (1) summary
      cd14058
      Location:32 → 282
      STKc_TAK1; Catalytic domain of the Serine/Threonine Kinase, Transforming Growth Factor beta Activated Kinase-1

    3. XM_044427610.1 → XP_044283545.1  mitogen-activated protein kinase kinase kinase 7 isoform X3

      UniProtKB/TrEMBL
      A0A8D2JKS3
      Related
      ENSVKKP00000012893.1, ENSVKKT00000013205.1
      Conserved Domains (1) summary
      cd14058
      Location:32 → 282
      STKc_TAK1; Catalytic domain of the Serine/Threonine Kinase, Transforming Growth Factor beta Activated Kinase-1

    4. XM_044427627.1 → XP_044283562.1  mitogen-activated protein kinase kinase kinase 7 isoform X5

      Conserved Domains (1) summary
      cd14058
      Location:32 → 282
      STKc_TAK1; Catalytic domain of the Serine/Threonine Kinase, Transforming Growth Factor beta Activated Kinase-1

    5. XM_044427592.1 → XP_044283527.1  mitogen-activated protein kinase kinase kinase 7 isoform X1

      UniProtKB/TrEMBL
      A0A8D2JJ08
      Related
      ENSVKKP00000012889.1, ENSVKKT00000013201.1
      Conserved Domains (1) summary
      cd14058
      Location:32 → 282
      STKc_TAK1; Catalytic domain of the Serine/Threonine Kinase, Transforming Growth Factor beta Activated Kinase-1

    6. XM_044427642.1 → XP_044283577.1  mitogen-activated protein kinase kinase kinase 7 isoform X6

      Conserved Domains (1) summary
      COG4942
      Location:47 → 141
      EnvC; Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning]

    RNA

    1. XR_006414477.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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