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    CDC42BPB CDC42 binding protein kinase beta [ Equus asinus (ass) ]

    Gene ID: 106839626, updated on 13-Mar-2024

    Summary

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    Gene symbol
    CDC42BPB
    Gene description
    CDC42 binding protein kinase beta
    See related
    Ensembl:ENSEASG00005004017
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus asinus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See CDC42BPB in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    101 current ASM1607732v2 (GCF_016077325.2) 7 NC_052183.1 (72066071..72199006, complement)
    100 previous assembly ASM130575v1 (GCF_001305755.1) Unplaced Scaffold NW_014638103.1 (1901526..1986807)

    Chromosome 7 - NC_052183.1Genomic Context describing neighboring genes Neighboring gene TNF receptor associated factor 3 Neighboring gene translation initiation factor IF-2-like Neighboring gene amnion associated transmembrane protein Neighboring gene LBH domain containing 2 Neighboring gene exocyst complex component 3 like 4 Neighboring gene TNF alpha induced protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actomyosin structure organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-threonine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actomyosin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase MRCK beta

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Equus asinus Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM1607732v2

    Genomic

    1. NC_052183.1 Reference ASM1607732v2

      Range
      72066071..72199006 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_044774358.1 → XP_044630293.1  serine/threonine-protein kinase MRCK beta isoform X2

      UniProtKB/TrEMBL
      A0A8C4L9E2
      Related
      ENSEASP00005005429.2, ENSEAST00005005934.2
      Conserved Domains (6) summary
      smart00109
      Location:971 → 1020
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      smart00285
      Location:1528 → 1555
      PBD; P21-Rho-binding domain
      COG0419
      Location:439 → 955
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd01243
      Location:1030 → 1164
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05624
      Location:3 → 411
      STKc_MRCK_beta; Catalytic domain of the Protein Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) beta
      cl02434
      Location:1195 → 1472
      CNH; CNH domain

    2. XM_044774357.1 → XP_044630292.1  serine/threonine-protein kinase MRCK beta isoform X1

      UniProtKB/TrEMBL
      A0A8C4L9C8, A0A8C4PH93
      Related
      ENSEASP00005005415.2, ENSEAST00005005920.2
      Conserved Domains (6) summary
      smart00109
      Location:1027 → 1076
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      smart00285
      Location:1584 → 1611
      PBD; P21-Rho-binding domain
      COG0419
      Location:439 → 955
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd01243
      Location:1086 → 1220
      PH_MRCK; MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain
      cd05624
      Location:3 → 411
      STKc_MRCK_beta; Catalytic domain of the Protein Serine/Threonine Kinase, DMPK-related cell division control protein 42 binding kinase (MRCK) beta
      cl02434
      Location:1251 → 1528
      CNH; CNH domain

    RNA

    1. XR_006530441.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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