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    LOC127821025 H3K27ac hESC enhancer GRCh37_chr11:47835433-47835933 [ Homo sapiens (human) ]

    Gene ID: 127821025, updated on 10-Oct-2023

    Summary

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    Gene symbol
    LOC127821025
    Gene description
    H3K27ac hESC enhancer GRCh37_chr11:47835433-47835933
    Gene type
    biological region
    Feature type(s)
    regulatory: enhancer
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Nov 2022]
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    Genomic context

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    See LOC127821025 in Genome Data Viewer
    Location:
    chromosome: 11
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (47813881..47814381)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (47978824..47979329)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene formin binding protein 4 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:47787258-47788183 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:47788184-47789108 Neighboring gene nucleoporin 160 Neighboring gene RNA, 5S ribosomal pseudogene 340 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:47834932-47835432 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4704 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4705 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4706 Neighboring gene YPEL5 pseudogene 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4707 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4708 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4709 Neighboring gene uncharacterized LOC124902844

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_122482.1 

      Range
      101..601
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      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      47813881..47814381
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      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_019805496.1 Reference GRCh38.p14 PATCHES

      Range
      246248..246748
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      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      47978824..47979329
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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