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    LOC127894981 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46185571-46186334 [ Homo sapiens (human) ]

    Gene ID: 127894981, updated on 10-Oct-2023

    Summary

    Gene symbol
    LOC127894981
    Gene description
    H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46185571-46186334
    Gene type
    biological region
    Feature type(s)
    regulatory: enhancer
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive and primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
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    Genomic context

    See LOC127894981 in Genome Data Viewer
    Location:
    chromosome: 21
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (44765656..44766419)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (43125917..43126676)

    Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene thrombospondin type laminin G domain and EAR repeats Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46116947-46117626 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46117627-46118306 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46122289-46123024 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46123025-46123760 Neighboring gene keratin associated protein 10-12 Neighboring gene keratin associated protein 10-13, pseudogene Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46129182-46129922 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46129923-46130663 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46130677-46131447 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46150268-46150768 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46150769-46151269 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46151907-46152582 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46152583-46153258 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46155285-46155958 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46155959-46156634 Neighboring gene Sharpr-MPRA regulatory region 5612 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46184321-46184886 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46186335-46187098 Neighboring gene Sharpr-MPRA regulatory region 676 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46188940-46189440 Neighboring gene ReSE screen-validated silencer GRCh37_chr21:46208307-46208531 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18575 Neighboring gene ubiquitin conjugating enzyme E2 G2 Neighboring gene H3K27ac hESC enhancer GRCh37_chr21:46220961-46221916 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13388 Neighboring gene long intergenic non-protein coding RNA 1424

    Genomic regions, transcripts, and products

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_144610.1 

      Range
      101..864
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

      Range
      44765656..44766419
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060945.1 Alternate T2T-CHM13v2.0

      Range
      43125917..43126676
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)