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    APOE apolipoprotein E [ Callithrix jacchus (white-tufted-ear marmoset) ]

    Gene ID: 100401608, updated on 3-Apr-2024

    Summary

    Gene symbol
    APOE
    Gene description
    apolipoprotein E
    See related
    Ensembl:ENSCJAG00000013062
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Callithrix jacchus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix
    Orthologs
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    Genomic context

    Location:
    chromosome: 22
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2023_03 current mCalJa1.2.pat.X (GCF_011100555.1) 22 NC_071463.1 (37693236..37697390)
    105 previous assembly Callithrix_jacchus_cj1700_1.1 (GCF_009663435.1) 22 NC_048404.1 (39016447..39020635)

    Chromosome 22 - NC_071463.1Genomic Context describing neighboring genes Neighboring gene nectin cell adhesion molecule 2 Neighboring gene translocase of outer mitochondrial membrane 40 Neighboring gene apolipoprotein C1 Neighboring gene apolipoprotein C4

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables amyloid-beta binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables low-density lipoprotein particle receptor binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables very-low-density lipoprotein particle receptor binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cholesterol catabolic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in lipid transport IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in lipoprotein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in negative regulation of neuron apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in positive regulation of nitric-oxide synthase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in regulation of amyloid-beta clearance IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    part_of intermediate-density lipoprotein particle IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_011100555.1-RS_2023_03

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCalJa1.2.pat.X

    Genomic

    1. NC_071463.1 Reference mCalJa1.2.pat.X

      Range
      37693236..37697390
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002762227.3XP_002762273.1  apolipoprotein E

      See identical proteins and their annotated locations for XP_002762273.1

      UniProtKB/TrEMBL
      U3D0I3, U3FTG7
      Related
      ENSCJAP00000023984.2
      Conserved Domains (1) summary
      pfam01442
      Location:88276
      Apolipoprotein; Apolipoprotein A1/A4/E domain
    2. XM_054250063.1XP_054106038.1  apolipoprotein E

      UniProtKB/TrEMBL
      U3FTG7