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    APOE apolipoprotein E [ Pteronotus mesoamericanus ]

    Gene ID: 129082847, updated on 2-Apr-2024

    Summary

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    Gene symbol
    APOE
    Gene description
    apolipoprotein E
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pteronotus mesoamericanus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Mormoopidae; Pteronotus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_03 current CSHL_Meso_final (GCF_021234165.1) Unplaced Scaffold NW_026555306.1 (2410866..2414044)

    NW_026555306.1Genomic Context describing neighboring genes Neighboring gene nectin cell adhesion molecule 2 Neighboring gene translocase of outer mitochondrial membrane 40 Neighboring gene uncharacterized LOC129082743 Neighboring gene apolipoprotein C1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_026555306 Unplaced Scaffold Reference CSHL_Meso_final

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables amyloid-beta binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables low-density lipoprotein particle receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables very-low-density lipoprotein particle receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cholesterol catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipoprotein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of neuron apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of nitric-oxide synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of amyloid-beta clearance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of intermediate-density lipoprotein particle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    apolipoprotein E

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_021234165.1-RS_2024_03

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CSHL_Meso_final

    Genomic

    1. NW_026555306.1 Reference CSHL_Meso_final

      Range
      2410866..2414044
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054588590.1 → XP_054444565.1  apolipoprotein E

    2. XM_054588591.1 → XP_054444566.1  apolipoprotein E

    Nucleotide Protein
    Heading Accession and Version

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