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    APOE apolipoprotein E [ Sorex fumeus (smoky shrew) ]

    Gene ID: 130043265, updated on 27-Mar-2024

    Summary

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    Gene symbol
    APOE
    Gene description
    apolipoprotein E
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sorex fumeus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Soricidae; Soricinae; Sorex
    Orthologs
    human mouse all
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    Genomic context

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    See APOE in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2023_10 current SorCin_2.1 (GCF_029834395.1) Unplaced Scaffold NW_026606179.1 (14368057..14370795, complement)

    NW_026606179.1Genomic Context describing neighboring genes Neighboring gene apolipoprotein C4 Neighboring gene apolipoprotein C1 Neighboring gene translocase of outer mitochondrial membrane 40 Neighboring gene nectin cell adhesion molecule 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_026606179 Unplaced Scaffold Reference SorFum_2.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables amyloid-beta binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables low-density lipoprotein particle receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables very-low-density lipoprotein particle receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cholesterol catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipoprotein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of neuron apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of nitric-oxide synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of amyloid-beta clearance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of intermediate-density lipoprotein particle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    apolipoprotein E

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_029834395.1-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference SorFum_2.1

    Genomic

    1. NW_026606179.1 Reference SorFum_2.1

      Range
      14368057..14370795 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_056135521.1 → XP_055991496.1  apolipoprotein E

    Nucleotide Protein
    Heading Accession and Version

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