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    LOC106551420 sodium channel protein type 4 subunit alpha-like [ Thamnophis sirtalis ]

    Gene ID: 106551420, updated on 22-Oct-2023

    Summary

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    Gene symbol
    LOC106551420
    Gene description
    sodium channel protein type 4 subunit alpha-like
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Thamnophis sirtalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Colubridae; Natricinae; Thamnophis
    Also known as
    SCN4a; NaV1.4
    Annotation information
    Annotation category: partial on reference assembly
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    Genomic context

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    See LOC106551420 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    100 current Thamnophis_sirtalis-6.0 (GCF_001077635.1) Unplaced Scaffold NW_013659399.1 (137946..172427)

    NW_013659399.1Genomic Context describing neighboring genes Neighboring gene POU domain, class 2, transcription factor 1-like Neighboring gene uncharacterized LOC106551421 Neighboring gene CD180 molecule Neighboring gene microtubule associated serine/threonine kinase family member 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_013659399.1 Unplaced Scaffold Reference Thamnophis_sirtalis-6.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables voltage-gated sodium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in membrane depolarization during action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuronal action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sodium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of voltage-gated sodium channel complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sodium channel protein type 4 subunit alpha-like
    Names
    sodium channel protein type 4 subunit alpha
    voltage-gated sodium channel type IV alpha subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Thamnophis sirtalis Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Thamnophis_sirtalis-6.0

    Genomic

    1. NW_013659399.1 Reference Thamnophis_sirtalis-6.0

      Range
      137946..172427
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014069529.1 → XP_013925004.1  sodium channel protein type 4 subunit alpha-like

      UniProtKB/TrEMBL
      A0A6I9YLV2, Q56PC7
      Conserved Domains (4) summary
      cd13433
      Location:1325 → 1377
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1074 → 1333
      Ion_trans; Ion transport protein
      pfam06512
      Location:853 → 1052
      Na_trans_assoc; Sodium ion transport-associated
      pfam16905
      Location:1649 → 1704
      GPHH; Voltage-dependent L-type calcium channel, IQ-associated
    Nucleotide Protein
    Heading Accession and Version

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