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    TFDP2 transcription factor Dp-2 [ Bos taurus (domestic cattle) ]

    Gene ID: 506114, updated on 10-Oct-2024

    Summary

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    Official Symbol
    TFDP2provided by VGNC
    Official Full Name
    transcription factor Dp-2provided by VGNC
    Primary source
    VGNC:VGNC:35786
    See related
    Ensembl:ENSBTAG00000006222
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See TFDP2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 1 NC_037328.1 (126827513..127032524)

    Chromosome 1 - NC_037328.1Genomic Context describing neighboring genes Neighboring gene 5'-3' exoribonuclease 1 Neighboring gene glycerol kinase 5 Neighboring gene large ribosomal subunit protein eL21-like Neighboring gene small ribosomal subunit protein eS12 Neighboring gene ATPase Na+/K+ transporting subunit beta 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription factor Dp-2
    Names
    transcription factor Dp-2 (E2F dimerization partner 2)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001428756.1 → NP_001415685.1  transcription factor Dp-2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      NKLS02000001

    2. NM_001428758.1 → NP_001415687.1  transcription factor Dp-2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      NKLS02000001
      UniProtKB/TrEMBL
      A0AAA9S749

    3. NM_001428759.1 → NP_001415688.1  transcription factor Dp-2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      NKLS02000001
      UniProtKB/TrEMBL
      A0AAA9S749

    4. NM_001428760.1 → NP_001415689.1  transcription factor Dp-2 isoform 3

      Status: VALIDATED

      Source sequence(s)
      NKLS02000001
      UniProtKB/TrEMBL
      A0A3Q1MKK9

    5. NM_001428761.1 → NP_001415690.1  transcription factor Dp-2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      NKLS02000001
      UniProtKB/TrEMBL
      A0AAA9TFR8

    6. NM_001428762.1 → NP_001415691.1  transcription factor Dp-2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      NKLS02000001
      UniProtKB/TrEMBL
      A0AAA9SCW8

    7. NM_001428763.1 → NP_001415692.1  transcription factor Dp-2 isoform 6

      Status: VALIDATED

      Source sequence(s)
      NKLS02000001
      UniProtKB/TrEMBL
      F1MN77

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037328.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      126827513..127032524
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005201851.5 → XP_005201908.1  transcription factor Dp-2 isoform X2

      See identical proteins and their annotated locations for XP_005201908.1

      UniProtKB/TrEMBL
      A0AAA9S749, F6RUC4
      Related
      ENSBTAP00000077991.1, ENSBTAT00000117205.1
      Conserved Domains (3) summary
      cd14458
      Location:218 → 264
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:133 → 213
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:220 → 358
      DP; Transcription factor DP

    2. XM_005201852.5 → XP_005201909.1  transcription factor Dp-2 isoform X2

      Conserved Domains (3) summary
      cd14458
      Location:218 → 264
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:133 → 213
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:220 → 358
      DP; Transcription factor DP

    3. XM_015473180.3 → XP_015328666.1  transcription factor Dp-2 isoform X2

      Conserved Domains (3) summary
      cd14458
      Location:218 → 264
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:133 → 213
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:220 → 358
      DP; Transcription factor DP

    4. XM_059891753.1 → XP_059747736.1  transcription factor Dp-2 isoform X3

      Related
      ENSBTAP00000072089.1, ENSBTAT00000076561.2

    5. XM_024998384.2 → XP_024854152.1  transcription factor Dp-2 isoform X7

      Related
      ENSBTAP00000095857.1, ENSBTAT00000130508.1
      Conserved Domains (3) summary
      cd14458
      Location:201 → 247
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:116 → 196
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:203 → 341
      DP; Transcription factor DP

    6. XM_024998189.2 → XP_024853957.1  transcription factor Dp-2 isoform X1

      Related
      ENSBTAP00000008169.5, ENSBTAT00000008169.6
      Conserved Domains (3) summary
      cd14458
      Location:224 → 270
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:139 → 219
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:226 → 364
      DP; Transcription factor DP

    7. XM_024998247.2 → XP_024854015.2  transcription factor Dp-2 isoform X4

    8. XM_005201857.5 → XP_005201914.1  transcription factor Dp-2 isoform X8

      Related
      ENSBTAP00000081370.1, ENSBTAT00000108619.1
      Conserved Domains (3) summary
      cd14458
      Location:154 → 200
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:69 → 149
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:156 → 294
      DP; Transcription factor DP

    9. XM_005201860.5 → XP_005201917.1  transcription factor Dp-2 isoform X9

      Related
      ENSBTAP00000008170.6, ENSBTAT00000008170.6
      Conserved Domains (3) summary
      cd14458
      Location:153 → 199
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:67 → 148
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:155 → 293
      DP; Transcription factor DP

    10. XM_005201855.4 → XP_005201912.1  transcription factor Dp-2 isoform X5

      UniProtKB/TrEMBL
      A0A3Q1MRQ6, A0AAA9TBJ5
      Related
      ENSBTAP00000094211.1, ENSBTAT00000126363.1
      Conserved Domains (3) summary
      cd14458
      Location:199 → 245
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:113 → 194
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:201 → 339
      DP; Transcription factor DP

    11. XM_059891869.1 → XP_059747852.1  transcription factor Dp-2 isoform X8

      UniProtKB/TrEMBL
      A0AAA9SCW8

    12. XM_024998313.2 → XP_024854081.1  transcription factor Dp-2 isoform X6

      UniProtKB/TrEMBL
      A0A3Q1MRQ6
      Related
      ENSBTAP00000074520.2, ENSBTAT00000086058.2
      Conserved Domains (3) summary
      cd14458
      Location:198 → 244
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:113 → 193
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:200 → 338
      DP; Transcription factor DP

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001075241.1: Suppressed sequence

      Description
      NM_001075241.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate. It encodes a partial protein, has a single nucleotide insertion relative to the genome, causing a frameshift.
    Nucleotide Protein Strain
    Heading Accession and Version

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