SEPTIN14P20 septin 14 pseudogene 20 [Homo sapiens (human)] - Gene

Summary

Official Symbol: SEPTIN14P20provided by HGNC
Official Full Name: septin 14 pseudogene 20provided by HGNC
Primary source: HGNC:HGNC:51706
See related: AllianceGenome:HGNC:51706
Gene type: pseudo
RefSeq status: PREDICTED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: RBRP; C20orf69; SEPT14P20; NCRNA00266; bA476I15.3; LINC00266-1; NCRNA00266-1
Summary: Involved in mRNA stabilization. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: 20q13.33

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	20	NC_000020.11 (64290385..64303354)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	20	NC_060944.1 (66110851..66123819)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	20	NC_000020.10 (62921738..62934707)

Chromosome 20 - NC_000020.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

LINC00266-1/miR-548c-3p/SMAD2 feedback loop stimulates the development of osteosarcoma.
Title: LINC00266-1/miR-548c-3p/SMAD2 feedback loop stimulates the development of osteosarcoma.
LncRNA LINC00266-1 encodes a 71-amino acid peptide that mainly interacts with the RNA-binding proteins and is thus named "RNA-binding regulatory peptide" (RBRP). RBRP binds to IGF2BP1 and strengthens m6A recognition by IGF2BP1 on RNAs, such as c-Myc mRNA, to increase the mRNA stability and expression of c-Myc, thereby promoting tumorigenesis. Cancer patients with RBRPhigh have a poor prognosis.
Title: An oncopeptide regulates m(6)A recognition by the m(6)A reader IGF2BP1 and tumorigenesis.

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Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Other Names

Putative RNA-binding regulatory peptide
RNA-binding regulatory peptide
long intergenic non-protein coding RNA 266-1

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in mRNA stabilization	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of mRNA binding	IDA Inferred from Direct Assay more info	PubMed

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.