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    PDYN prodynorphin [ Pan troglodytes (chimpanzee) ]

    Gene ID: 469860, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PDYNprovided by VGNC
    Official Full Name
    prodynorphinprovided by VGNC
    Primary source
    VGNC:VGNC:6231
    Locus tag
    CK820_G0017437
    See related
    Ensembl:ENSPTRG00000013172
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    See PDYN in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 21 NC_072419.2 (8613567..8632288, complement)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 20 NC_072418.1 (2000384..2024529)

    Chromosome 21 - NC_072419.2Genomic Context describing neighboring genes Neighboring gene signal regulatory protein alpha Neighboring gene uncharacterized LOC107969908 Neighboring gene serine/threonine kinase 35 Neighboring gene transglutaminase 3 Neighboring gene transglutaminase 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ancient and recent positive selection transformed opioid cis-regulation in humans. Rockman MV, et al. PLoS Biol, 2005 Dec. PMID 16274263, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables opioid receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuropeptide signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sensory perception IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon terminus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in dendrite IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuronal cell body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    proenkephalin-B
    Names
    beta-neoendorphin-dynorphin
    preprodynorphin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072419.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      8613567..8632288 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_016937317.4 → XP_016792806.1  proenkephalin-B

      UniProtKB/TrEMBL
      A0A2J8MS47, A0A6D2XQA9, H2QJT9, Q2YEK1, Q2YEK2, Q2YEK4
      Conserved Domains (1) summary
      pfam01160
      Location:21 → 67
      Opiods_neuropep; Vertebrate endogenous opioids neuropeptide

    2. XM_009436699.5 → XP_009434974.1  proenkephalin-B

      See identical proteins and their annotated locations for XP_009434974.1

      UniProtKB/TrEMBL
      A0A2J8MS47, A0A6D2XQA9, H2QJT9, Q2YEK1, Q2YEK2, Q2YEK4
      Conserved Domains (1) summary
      pfam01160
      Location:21 → 67
      Opiods_neuropep; Vertebrate endogenous opioids neuropeptide

    3. XM_001155165.7 → XP_001155165.1  proenkephalin-B

      See identical proteins and their annotated locations for XP_001155165.1

      UniProtKB/TrEMBL
      A0A2J8MS47, A0A6D2XQA9, H2QJT9, Q2YEK1, Q2YEK2, Q2YEK4
      Related
      ENSPTRP00000022551.3
      Conserved Domains (1) summary
      pfam01160
      Location:21 → 67
      Opiods_neuropep; Vertebrate endogenous opioids neuropeptide
    Nucleotide Protein
    Heading Accession and Version

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