U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Nucleotide

    • Showing Current items.

    IP6K2 inositol hexakisphosphate kinase 2 [ Homo sapiens (human) ]

    Gene ID: 51447, updated on 14-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    IP6K2provided by HGNC
    Official Full Name
    inositol hexakisphosphate kinase 2provided by HGNC
    Primary source
    HGNC:HGNC:17313
    See related
    Ensembl:ENSG00000068745 MIM:606992; AllianceGenome:HGNC:17313
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PIUS; IHPK2; InsP6K2
    Summary
    This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
    Expression
    Ubiquitous expression in bone marrow (RPKM 16.6), skin (RPKM 16.3) and 25 other tissues See more
    Orthologs
    mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See IP6K2 in Genome Data Viewer
    Location:
    3p21.31
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (48688003..48717221, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (48716988..48746201, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (48725436..48754654, complement)

    Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19841 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19842 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:48702141-48702725 Neighboring gene long intergenic non-protein coding RNA 2585 Neighboring gene Sharpr-MPRA regulatory region 90 Neighboring gene NCK interacting protein with SH3 domain Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:48725238-48725738 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:48725739-48726239 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:48732697-48733286 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:48750133-48750632 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14339 Neighboring gene protein kinase cAMP-dependent type II regulatory subunit alpha Neighboring gene MPRA-validated peak4643 silencer Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:48806609-48807260 Neighboring gene MPRA-validated peak4644 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14340 Neighboring gene PRKAR2A antisense RNA 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Inositol hexakisphosphate kinase-2, a physiologic mediator of cell death. Nagata E, et al. J Biol Chem, 2005 Jan 14. PMID 15533939
    2. Inositol hexakisphosphate kinase 2 sensitizes ovarian carcinoma cells to multiple cancer therapeutics. Morrison BH, et al. Oncogene, 2002 Mar 14. PMID 11896621, Free PMC Article
    3. Inositol hexakisphosphate kinase 2 promotes cell death of anterior horn cells in the spinal cord of patients with amyotrophic lateral sclerosis. Nagata E, et al. Mol Biol Rep, 2020 Sep. PMID 32929655
    4. Casein kinase-2 mediates cell survival through phosphorylation and degradation of inositol hexakisphosphate kinase-2. Chakraborty A, et al. Proc Natl Acad Sci U S A, 2011 Feb 8. PMID 21262846, Free PMC Article
    5. IP6K structure and the molecular determinants of catalytic specificity in an inositol phosphate kinase family. Wang H, et al. Nat Commun, 2014 Jun 24. PMID 24956979, Free PMC Article

    See all (49) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Circ-IP6K2 suppresses tumor progression by modulating the miR-1292-5p/CAMK2N1 signal in clear cell renal cell carcinoma.
      Title: Circ-IP6K2 suppresses tumor progression by modulating the miR-1292-5p/CAMK2N1 signal in clear cell renal cell carcinoma.
    2. Inositol hexakisphosphate kinase 2 promotes cell death of anterior horn cells in the spinal cord of patients with amyotrophic lateral sclerosis.
      Title: Inositol hexakisphosphate kinase 2 promotes cell death of anterior horn cells in the spinal cord of patients with amyotrophic lateral sclerosis.
    3. LINC00467 knockdown repressed cell proliferation but stimulated cell apoptosis in glioblastoma via miR-339-3p/IP6K2 axis.
      Title: LINC00467 knockdown repressed cell proliferation but stimulated cell apoptosis in glioblastoma via miR-339-3p/IP6K2 axis.
    4. conclude that IP6K1 and -2 together control inositol pyrophosphate metabolism and thereby physiologically regulate phosphate export and other aspects of mammalian cellular phosphate homeostasis
      Title: The inositol hexakisphosphate kinases IP6K1 and -2 regulate human cellular phosphate homeostasis, including XPR1-mediated phosphate export.
    5. An alpha-helical pair and a rare, two-turn 310 helix, that together form a substrate-binding pocket of IP6K2.
      Title: IP6K structure and the molecular determinants of catalytic specificity in an inositol phosphate kinase family.
    6. FGF2-signaling involves the inositol polyphosphate cascade, including inositol hexakisphosphate kinase (IP6K), and demonstrate that IP6K1,2 regulates Runx2 and osteoblast gene expression.
      Title: The regulation of runt-related transcription factor 2 by fibroblast growth factor-2 and connexin43 requires the inositol polyphosphate/protein kinase Cδ cascade.
    7. Genetic polymorphisms in IP6K2 gene is associated with autoimmune disease.
      Title: Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles.
    8. Casein kinase-2 mediates cell survival through phosphorylation and degradation of inositol hexakisphosphate kinase-2.
      Title: Casein kinase-2 mediates cell survival through phosphorylation and degradation of inositol hexakisphosphate kinase-2.
    9. Gene disruption of IP6K2 in colorectal cancer cells selectively impairs p53-mediated apoptosis, instead favoring cell-cycle arrest. IP6K2 acts by binding directly to p53 and decreasing expression of proarrest gene targets
      Title: p53-mediated apoptosis requires inositol hexakisphosphate kinase-2.
    10. InsP6K2 is a physiologic mediator of cell death
      Title: Inositol hexakisphosphate kinase-2, a physiologic mediator of cell death.
    Submit: New GeneRIF Correction See all GeneRIFs (12)

    Phenotypes

    Go to the top of the page Help

    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    A genome-wide association study identifies a novel locus at 6q22.1 associated with ulcerative colitis.
    EBI GWAS Catalog
    Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
    EBI GWAS Catalog

    Variation

    Go to the top of the page Help

    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables diphosphoinositol pentakisphosphate kinase activity TAS
    Traceable Author Statement
    more info
    		  
    enables diphosphoinositol tetrakisphosphate kinase activity TAS
    Traceable Author Statement
    more info
    		  
    enables flavonoid binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables inositol 5-diphosphate pentakisphosphate 5-kinase activity TAS
    Traceable Author Statement
    more info
    		  
    enables inositol hexakisphosphate 5-kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables inositol hexakisphosphate kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables inositol hexakisphosphate kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables inositol hexakisphosphate kinase activity TAS
    Traceable Author Statement
    more info
    		  
    enables inositol-1,3,4,5,6-pentakisphosphate kinase activity TAS
    Traceable Author Statement
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to flavonoid IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in inositol phosphate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in inositol phosphate metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in inositol phosphate metabolic process TAS
    Traceable Author Statement
    more info
    		  
    involved_in negative regulation of cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in phosphatidylinositol phosphate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phosphatidylinositol phosphate biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein stabilization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell junction IDA
    Inferred from Direct Assay
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in fibrillar center IDA
    Inferred from Direct Assay
    more info
    		  
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		  
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    inositol hexakisphosphate kinase 2
    Names
    ATP:1D-myo-inositol-hexakisphosphate phosphotransferase
    inositol hexaphosphate kinase 2
    insp6 kinase 2
    pi uptake stimulator
    NP_001005909.1
    NP_001005910.1
    NP_001005911.1
    NP_001139650.1
    NP_001139651.1
    NP_001177245.1
    NP_001177246.1
    NP_057375.2
    XP_006713262.1
    XP_006713263.1
    XP_006713264.1
    XP_006713265.1
    XP_011532118.1
    XP_011532120.1
    XP_016862078.1
    XP_016862079.1
    XP_016862080.1
    XP_016862081.1
    XP_024309336.1
    XP_024309339.1
    XP_047304247.1
    XP_047304248.1
    XP_047304249.1
    XP_047304250.1
    XP_054202773.1
    XP_054202774.1
    XP_054202775.1
    XP_054202776.1
    XP_054202777.1
    XP_054202778.1
    XP_054202779.1
    XP_054202780.1
    XP_054202781.1
    XP_054202782.1
    XP_054202783.1
    XP_054202784.1
    XP_054202785.1
    XP_054202786.1
    XP_054202787.1
    XP_054202788.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005909.3 → NP_001005909.1  inositol hexakisphosphate kinase 2 isoform a

      See identical proteins and their annotated locations for NP_001005909.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (a).
      Source sequence(s)
      AC141002, AY007091, DB039955
      Consensus CDS
      CCDS2777.1
      UniProtKB/Swiss-Prot
      A8K3B1, B4E3G6, G8JLL6, Q6P0N8, Q9BSZ6, Q9BUW3, Q9H4P7, Q9NT63, Q9UFU6, Q9UHH9
      UniProtKB/TrEMBL
      B2RCP4
      Conserved Domains (1) summary
      pfam03770
      Location:203 → 418
      IPK; Inositol polyphosphate kinase

    2. NM_001005910.3 → NP_001005910.1  inositol hexakisphosphate kinase 2 isoform b

      See identical proteins and their annotated locations for NP_001005910.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) differs in the 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (b) has a distinct C-terminus and is shorter than isoform a. Variants 3 and 4 encode the same isoform (b).
      Source sequence(s)
      AL137514, DB039955
      Consensus CDS
      CCDS33752.1
      UniProtKB/Swiss-Prot
      Q9UHH9
      Related
      ENSP00000341925.4, ENST00000340879.8

    3. NM_001005911.3 → NP_001005911.1  inositol hexakisphosphate kinase 2 isoform b

      See identical proteins and their annotated locations for NP_001005911.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) uses an alternate in-frame splice site in the 5' UTR and differs in the 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (b) has a distinct C-terminus and is shorter than isoform a. Variants 3 and 4 encode the same isoform (b).
      Source sequence(s)
      AL137514, CN362780, DB039955
      Consensus CDS
      CCDS33752.1
      UniProtKB/Swiss-Prot
      Q9UHH9

    4. NM_001146178.3 → NP_001139650.1  inositol hexakisphosphate kinase 2 isoform c

      See identical proteins and their annotated locations for NP_001139650.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (c) has a shorter and distinct C-terminus compared to isoform a. Variants 5 and 6 encode the same isoform (c).
      Source sequence(s)
      AL137514, CA488567, DB039955
      Consensus CDS
      CCDS54579.1
      UniProtKB/TrEMBL
      C9JGK2
      Related
      ENSP00000400812.2, ENST00000432678.6

    5. NM_001146179.3 → NP_001139651.1  inositol hexakisphosphate kinase 2 isoform c

      See identical proteins and their annotated locations for NP_001139651.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) uses an alternate in-frame splice site in the 5' UTR and differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (c) has a shorter and distinct C-terminus compared to isoform a. Variants 5 and 6 encode the same isoform (c).
      Source sequence(s)
      AL137514, DA083858, DB039955
      Consensus CDS
      CCDS54579.1
      UniProtKB/TrEMBL
      C9JGK2

    6. NM_001190316.2 → NP_001177245.1  inositol hexakisphosphate kinase 2 isoform d

      See identical proteins and their annotated locations for NP_001177245.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) has multiple differences compared to variant 1. These differences result in translation initiation at an alternate start codon, compared to variant 1. The encoded protein (isoform d) has distinct N- and C-termini and shorter than isoform a.
      Source sequence(s)
      AL137514, BX537544, DB039955
      Consensus CDS
      CCDS54580.1
      UniProtKB/TrEMBL
      A8K636
      Related
      ENSP00000414139.2, ENST00000431721.6

    7. NM_001190317.2 → NP_001177246.1  inositol hexakisphosphate kinase 2 isoform e

      See identical proteins and their annotated locations for NP_001177246.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10) has multiple differences compared to variant 1. These differences result in translation initiation at an alternate start codon, compared to variant 1. The encoded protein (isoform e) has distinct N- and C-termini and shorter than isoform a.
      Source sequence(s)
      AK304714, AL137514, BX537544, DB039955
      Consensus CDS
      CCDS54581.1
      UniProtKB/TrEMBL
      C9J8W6
      Related
      ENSP00000399052.1, ENST00000446860.5

    8. NM_016291.4 → NP_057375.2  inositol hexakisphosphate kinase 2 isoform a

      See identical proteins and their annotated locations for NP_057375.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (a). Variants 1 and 2 encode the same isoform (a).
      Source sequence(s)
      AK315204, AY007091, DB039955
      Consensus CDS
      CCDS2777.1
      UniProtKB/Swiss-Prot
      A8K3B1, B4E3G6, G8JLL6, Q6P0N8, Q9BSZ6, Q9BUW3, Q9H4P7, Q9NT63, Q9UFU6, Q9UHH9
      UniProtKB/TrEMBL
      B2RCP4
      Related
      ENSP00000331103.5, ENST00000328631.10
      Conserved Domains (1) summary
      pfam03770
      Location:203 → 418
      IPK; Inositol polyphosphate kinase

    RNA

    1. NR_027437.3 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) differs in the 3' terminal exons compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AL137514, CD248129, DB039955

    2. NR_027438.3 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) has multiple differences compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AL137514, BC001864, DB039955
      Related
      ENST00000416707.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

      Range
      48688003..48717221 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006713200.2 → XP_006713263.1  inositol hexakisphosphate kinase 2 isoform X2

      See identical proteins and their annotated locations for XP_006713263.1

      Conserved Domains (1) summary
      pfam03770
      Location:261 → 476
      IPK; Inositol polyphosphate kinase

    2. XM_006713199.5 → XP_006713262.1  inositol hexakisphosphate kinase 2 isoform X1

      See identical proteins and their annotated locations for XP_006713262.1

      Conserved Domains (1) summary
      pfam03770
      Location:262 → 477
      IPK; Inositol polyphosphate kinase

    3. XM_024453571.2 → XP_024309339.1  inositol hexakisphosphate kinase 2 isoform X5

      UniProtKB/Swiss-Prot
      A8K3B1, B4E3G6, G8JLL6, Q6P0N8, Q9BSZ6, Q9BUW3, Q9H4P7, Q9NT63, Q9UFU6, Q9UHH9
      UniProtKB/TrEMBL
      B2RCP4
      Conserved Domains (1) summary
      pfam03770
      Location:203 → 418
      IPK; Inositol polyphosphate kinase

    4. XM_024453568.2 → XP_024309336.1  inositol hexakisphosphate kinase 2 isoform X5

      UniProtKB/Swiss-Prot
      A8K3B1, B4E3G6, G8JLL6, Q6P0N8, Q9BSZ6, Q9BUW3, Q9H4P7, Q9NT63, Q9UFU6, Q9UHH9
      UniProtKB/TrEMBL
      B2RCP4
      Conserved Domains (1) summary
      pfam03770
      Location:203 → 418
      IPK; Inositol polyphosphate kinase

    5. XM_006713202.3 → XP_006713265.1  inositol hexakisphosphate kinase 2 isoform X4

      See identical proteins and their annotated locations for XP_006713265.1

      Conserved Domains (1) summary
      pfam03770
      Location:257 → 472
      IPK; Inositol polyphosphate kinase

    6. XM_006713201.3 → XP_006713264.1  inositol hexakisphosphate kinase 2 isoform X3

      See identical proteins and their annotated locations for XP_006713264.1

      Conserved Domains (1) summary
      pfam03770
      Location:258 → 473
      IPK; Inositol polyphosphate kinase

    7. XM_047448292.1 → XP_047304248.1  inositol hexakisphosphate kinase 2 isoform X2

    8. XM_047448291.1 → XP_047304247.1  inositol hexakisphosphate kinase 2 isoform X1

    9. XM_011533816.3 → XP_011532118.1  inositol hexakisphosphate kinase 2 isoform X4

      See identical proteins and their annotated locations for XP_011532118.1

      Conserved Domains (1) summary
      pfam03770
      Location:257 → 472
      IPK; Inositol polyphosphate kinase

    10. XM_047448293.1 → XP_047304249.1  inositol hexakisphosphate kinase 2 isoform X3

    11. XM_011533818.2 → XP_011532120.1  inositol hexakisphosphate kinase 2 isoform X6

      See identical proteins and their annotated locations for XP_011532120.1

      Conserved Domains (1) summary
      pfam03770
      Location:165 → 380
      IPK; Inositol polyphosphate kinase

    12. XM_017006591.2 → XP_016862080.1  inositol hexakisphosphate kinase 2 isoform X8

      UniProtKB/TrEMBL
      C9J3W9
      Related
      ENSP00000410454.1, ENST00000455545.5

    13. XM_017006589.2 → XP_016862078.1  inositol hexakisphosphate kinase 2 isoform X7

      UniProtKB/TrEMBL
      C9J3W9

    14. XM_047448294.1 → XP_047304250.1  inositol hexakisphosphate kinase 2 isoform X9

      UniProtKB/TrEMBL
      C9JRM0
      Related
      ENSP00000394488.1, ENST00000450045.5

    15. XM_017006590.3 → XP_016862079.1  inositol hexakisphosphate kinase 2 isoform X7

      UniProtKB/TrEMBL
      C9J3W9

    16. XM_017006592.2 → XP_016862081.1  inositol hexakisphosphate kinase 2 isoform X10

      UniProtKB/TrEMBL
      F8WDQ5

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060927.1 Alternate T2T-CHM13v2.0

      Range
      48716988..48746201 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054346800.1 → XP_054202775.1  inositol hexakisphosphate kinase 2 isoform X2

    2. XM_054346798.1 → XP_054202773.1  inositol hexakisphosphate kinase 2 isoform X1

    3. XM_054346806.1 → XP_054202781.1  inositol hexakisphosphate kinase 2 isoform X5

      UniProtKB/Swiss-Prot
      A8K3B1, B4E3G6, G8JLL6, Q6P0N8, Q9BSZ6, Q9BUW3, Q9H4P7, Q9NT63, Q9UFU6, Q9UHH9
      UniProtKB/TrEMBL
      B2RCP4

    4. XM_054346807.1 → XP_054202782.1  inositol hexakisphosphate kinase 2 isoform X5

      UniProtKB/Swiss-Prot
      A8K3B1, B4E3G6, G8JLL6, Q6P0N8, Q9BSZ6, Q9BUW3, Q9H4P7, Q9NT63, Q9UFU6, Q9UHH9
      UniProtKB/TrEMBL
      B2RCP4

    5. XM_054346804.1 → XP_054202779.1  inositol hexakisphosphate kinase 2 isoform X4

    6. XM_054346802.1 → XP_054202777.1  inositol hexakisphosphate kinase 2 isoform X3

    7. XM_054346801.1 → XP_054202776.1  inositol hexakisphosphate kinase 2 isoform X2

    8. XM_054346799.1 → XP_054202774.1  inositol hexakisphosphate kinase 2 isoform X1

    9. XM_054346805.1 → XP_054202780.1  inositol hexakisphosphate kinase 2 isoform X4

    10. XM_054346803.1 → XP_054202778.1  inositol hexakisphosphate kinase 2 isoform X3

    11. XM_054346808.1 → XP_054202783.1  inositol hexakisphosphate kinase 2 isoform X6

    12. XM_054346811.1 → XP_054202786.1  inositol hexakisphosphate kinase 2 isoform X8

    13. XM_054346809.1 → XP_054202784.1  inositol hexakisphosphate kinase 2 isoform X7

    14. XM_054346812.1 → XP_054202787.1  inositol hexakisphosphate kinase 2 isoform X9

      UniProtKB/TrEMBL
      C9JRM0

    15. XM_054346810.1 → XP_054202785.1  inositol hexakisphosphate kinase 2 isoform X7

    16. XM_054346813.1 → XP_054202788.1  inositol hexakisphosphate kinase 2 isoform X10

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001005912.1: Suppressed sequence

      Description
      NM_001005912.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.

    2. NM_001005913.1: Suppressed sequence

      Description
      NM_001005913.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9UHH9.2 GenPept UniProtKB/Swiss-Prot:Q9UHH9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous