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    Rho GTPase activating protein with PAK-box/P21-Rho-binding domain-containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832301, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Rho GTPase activating protein with PAK-box/P21-Rho-binding domain-containing protein
    Primary source
    TAIR:AT5G22400
    Locus tag
    AT5G22400
    See related
    Araport:AT5G22400
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MWD9.20; MWD9_20
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (7422670..7425574, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene FANTASTIC four-like protein (DUF3049) Neighboring gene ncRNA Neighboring gene root hair specific 18 Neighboring gene fatty acid reductase 7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ROPGAPs of Arabidopsis limit susceptibility to powdery mildew. Huesmann C, et al. Plant Signal Behav, 2011 Nov. PMID 22067988, Free PMC Article
    2. Arabidopsis RopGAPs are a novel family of rho GTPase-activating proteins that require the Cdc42/Rac-interactive binding motif for rop-specific GTPase stimulation. Wu G, et al. Plant Physiol, 2000 Dec. PMID 11115880, Free PMC Article
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_122145.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Rho GTPase activating protein with PAK-box/P21-Rho-binding domain-containing protein
    NP_197632.1
    • Rho GTPase activating protein with PAK-box/P21-Rho-binding domain; FUNCTIONS IN: Rac GTPase activator activity; INVOLVED IN: signal transduction; LOCATED IN: intracellular, chloroplast; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: PAK-box/P21-Rho-binding (InterPro:IPR000095), Rho GTPase activation protein (InterPro:IPR008936), RhoGAP (InterPro:IPR000198); BEST Arabidopsis thaliana protein match is: rac GTPase activating protein (TAIR:AT3G11490.1); Has 3977 Blast hits to 3976 proteins in 184 species: Archae - 0; Bacteria - 0; Metazoa - 2927; Fungi - 443; Plants - 206; Viruses - 0; Other Eukaryotes - 401 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      7422670..7425574 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122145.5 → NP_197632.1  Rho GTPase activating protein with PAK-box/P21-Rho-binding domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197632.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FMR1
      UniProtKB/TrEMBL
      A0A178UPX4
      Conserved Domains (2) summary
      smart00324
      Location:178 → 337
      RhoGAP; GTPase-activator protein for Rho-like GTPases
      cd00132
      Location:115 → 155
      CRIB; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FMR1.1

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