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    HSD17B7P2 hydroxysteroid 17-beta dehydrogenase 7 pseudogene 2 [ Homo sapiens (human) ]

    Gene ID: 158160, updated on 22-Oct-2024

    Summary

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    Official Symbol
    HSD17B7P2provided by HGNC
    Official Full Name
    hydroxysteroid 17-beta dehydrogenase 7 pseudogene 2provided by HGNC
    Primary source
    HGNC:HGNC:28120
    See related
    Ensembl:ENSG00000290439 AllianceGenome:HGNC:28120
    Gene type
    pseudo
    RefSeq status
    PROVISIONAL
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HSD17B7; Hsd17b_2; bA291L22.1
    Expression
    Ubiquitous expression in prostate (RPKM 3.6), lymph node (RPKM 3.5) and 25 other tissues See more
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    Genomic context

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    See HSD17B7P2 in Genome Data Viewer
    Location:
    10p11.1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (38356380..38378505)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (38400377..38422500)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (38645308..38667433)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene cyclin Y like 4 (pseudogene) Neighboring gene PLD5 pseudogene 1 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:38644965-38645522 Neighboring gene septin 7 pseudogene 9 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:38690995-38691866 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:38691867-38692738 Neighboring gene uncharacterized LOC101929540 Neighboring gene RNA, U6 small nuclear 1118, pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Cloning and characterization of human form 2 type 7 17beta-hydroxysteroid dehydrogenase, a primarily 3beta-keto reductase and estrogen activating and androgen inactivating enzyme. Liu H, et al. J Steroid Biochem Mol Biol, 2005 Feb. PMID 15862963
    2. Determination of cDNA, gene structure and chromosomal localization of the novel human 17beta-hydroxysteroid dehydrogenase type 7(1). Krazeisen A, et al. FEBS Lett, 1999 Oct 29. PMID 10544267
    3. Production, purification, and functional analysis of recombinant human and mouse 17beta-hydroxysteroid dehydrogenase type 7. Törn S, et al. Biochem Biophys Res Commun, 2003 May 23. PMID 12732193
    4. Closing the gap: identification of human 3-ketosteroid reductase, the last unknown enzyme of mammalian cholesterol biosynthesis. Marijanovic Z, et al. Mol Endocrinol, 2003 Sep. PMID 12829805
    5. Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Fei T, et al. Proc Natl Acad Sci U S A, 2017 Jun 27. PMID 28611215, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Other Names

    • 17beta-hydroxysteroid dehydrogenase type 7 form 2

    Clone Names

    • FLJ40773, MGC88684

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_003086.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      BC071987
      Related
      ENST00000494540.6

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      38356380..38378505
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_021160000.1 Reference GRCh38.p14 PATCHES

      Range
      290..15333
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      38400377..38422500
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001031744.1: Suppressed sequence

      Description
      NM_001031744.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.

    2. NM_182829.1: Suppressed sequence

      Description
      NM_182829.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
    Nucleotide Protein
    Heading Accession and Version

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