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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_008055.1 RefSeqGene
- Range
-
5001..10238
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_256
mRNA and Protein(s)
-
NM_000530.8 → NP_000521.2 myelin protein P0 isoform MPZ precursor
See identical proteins and their annotated locations for NP_000521.2
Status: REVIEWED
- Description
- Transcript Variant: This transcript (1) encodes two isoforms, which result from the use of alternative in-frame translation termination codons. The shorter isoform (MPZ, also known as P0) results from translation termination at the upstream UAG stop codon, while the longer isoform (L-MPZ) results from UAG stop codon readthrough to the downstream UGA termination codon. This RefSeq represents the shorter isoform (MPZ).
- Source sequence(s)
-
BM663255, CD172418, D10537, DB210759
- Consensus CDS
-
CCDS1229.2
- UniProtKB/Swiss-Prot
- P25189, Q16072, Q5VTH4, Q92677, Q9BR67
- UniProtKB/TrEMBL
-
A0A0J9YWT2
- Related
- ENSP00000432943.1, ENST00000533357.5
- Conserved Domains (2) summary
-
- cd05879
Location:31 → 146
- Ig_P0; Immunoglobulin (Ig)-like domain of Protein zero (P0)
- pfam10570
Location:184 → 248
- Myelin-PO_C; Myelin-PO cytoplasmic C-term p65 binding region
-
NM_001315491.2 → NP_001302420.1 myelin protein P0 isoform L-MPZ precursor
Status: REVIEWED
- Description
- Transcript Variant: This transcript (1) encodes two isoforms, which result from the use of alternative in-frame translation termination codons. The shorter isoform (MPZ, also known as P0) results from translation termination at the upstream UAG stop codon, while the longer isoform (L-MPZ) results from UAG stop codon readthrough to the downstream UGA termination codon. This RefSeq represents the longer, C-terminally extended isoform (L-MPZ). As the UAG stop codon has been reported to specify several alternative amino acids (glutamine, tyrosine and leucine), its location in the longer isoform is denoted by an 'X'.
- Source sequence(s)
-
BM663255, CD172418, D10537, DB210759
- Consensus CDS
-
CCDS91087.1
- UniProtKB/TrEMBL
-
A0A5F9ZI26
- Related
- ENSP00000500814.2, ENST00000672602.2
- Conserved Domains (3) summary
-
- cd05879
Location:31 → 146
- Ig_P0; Immunoglobulin (Ig)-like domain of Protein zero (P0)
- smart00410
Location:36 → 146
- IG_like; Immunoglobulin like
- pfam10570
Location:184 → 248
- Myelin-PO_C; Myelin-PO cytoplasmic C-term p65 binding region
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000001.11 Reference GRCh38.p14 Primary Assembly
- Range
-
161303600..161309968 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_017001321.3 → XP_016856810.1 myelin protein P0 isoform X1
- UniProtKB/TrEMBL
-
Q14902
Alternate T2T-CHM13v2.0
Genomic
-
NC_060925.1 Alternate T2T-CHM13v2.0
- Range
-
160441004..160447413 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054336676.1 → XP_054192651.1 myelin protein P0 isoform X1