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    LOC116522989 sodium channel protein type 4 subunit alpha-like [ Thamnophis elegans (Western terrestrial garter snake) ]

    Gene ID: 116522989, updated on 14-Dec-2023

    Summary

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    Gene symbol
    LOC116522989
    Gene description
    sodium channel protein type 4 subunit alpha-like
    See related
    EnsemblRapid:ENSTELG00000016727
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Thamnophis elegans
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Colubridae; Natricinae; Thamnophis
    Also known as
    SCN4A
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    Genomic context

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    See LOC116522989 in Genome Data Viewer
    Location:
    chromosome: Z
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    100 current rThaEle1.pri (GCF_009769535.1) Z NC_045558.1 (92209578..92280138)

    Chromosome Z - NC_045558.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 43 Neighboring gene ADAM metallopeptidase domain 11 Neighboring gene uncharacterized protein K02A2.6-like Neighboring gene zinc finger BED domain-containing protein 5-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_045558.1 Chromosome Z Reference rThaEle1.pri

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The evolutionary origins of beneficial alleles during the repeated adaptation of garter snakes to deadly prey. Feldman CR, et al. Proc Natl Acad Sci U S A, 2009 Aug 11. PMID 19666534, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables voltage-gated sodium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in membrane depolarization during action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuronal action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sodium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of voltage-gated sodium channel complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sodium channel protein type 4 subunit alpha-like
    Names
    skeletal muscle voltage-gated sodium channel
    voltage-gated sodium channel

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Thamnophis elegans Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference rThaEle1.pri

    Genomic

    1. NC_045558.1 Reference rThaEle1.pri

      Range
      92209578..92280138
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_032238132.1 → XP_032094023.1  sodium channel protein type 4 subunit alpha-like isoform X2

      UniProtKB/TrEMBL
      C7AKA0
      Related
      ENSTELP00000023465.1, ENSTELT00000024675.1
      Conserved Domains (3) summary
      cd13433
      Location:1325 → 1377
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1056 → 1333
      Ion_trans; Ion transport protein
      pfam06512
      Location:853 → 1052
      Na_trans_assoc; Sodium ion transport-associated

    2. XM_032238131.1 → XP_032094022.1  sodium channel protein type 4 subunit alpha-like isoform X1

      UniProtKB/TrEMBL
      C7AKA0
      Conserved Domains (3) summary
      cd13433
      Location:1328 → 1380
      Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
      pfam00520
      Location:1059 → 1336
      Ion_trans; Ion transport protein
      pfam06512
      Location:853 → 1055
      Na_trans_assoc; Sodium ion transport-associated
    Nucleotide Protein
    Heading Accession and Version

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