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    clec-149 C-type lectin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 186903, updated on 2-Nov-2024

    Summary

    Official Symbol
    clec-149
    Official Full Name
    C-type lectin domain-containing protein
    Primary source
    WormBase:WBGene00019328
    Locus tag
    CELE_K02F3.5
    See related
    AllianceGenome:WB:WBGene00019328
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable carbohydrate binding activity and pattern recognition receptor activity. Predicted to be involved in immune response. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in Coronavirus infectious disease; aspergillosis; dengue disease (multiple); human immunodeficiency virus infectious disease (multiple); and tuberculosis (multiple). Orthologous to human CD209 (CD209 molecule) and FCER2 (Fc epsilon receptor II). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See clec-149 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    5
    Sequence:
    Chromosome: III; NC_003281.10 (823222..826408)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Dauer larva development regulatory growth factor daf-7 Neighboring gene Dachshund homolog dac-1 Neighboring gene ncRNA Neighboring gene Epoxide hydrolase 1 Neighboring gene ncRNA

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables carbohydrate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables pattern recognition receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    C-type lectin domain-containing protein
    NP_497267.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      823222..826408
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064866.5NP_497267.2  C-type lectin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497267.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q21146
      Conserved Domains (1) summary
      cd00037
      Location:197306
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain