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    Sp2 sex-specific storage-protein 2 [ Bombyx mori (domestic silkworm) ]

    Gene ID: 733005, updated on 9-Feb-2024

    Summary

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    Gene symbol
    Sp2
    Gene description
    sex-specific storage-protein 2
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bombyx mori
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea; Bombycidae; Bombycinae; Bombyx
    Annotation information
    Annotation category: partial on reference assembly
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    Genomic context

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    See Sp2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_01 current ASM3026992v2 (GCF_030269925.1) 3 NC_085109.1 (6988477..6992905, complement)
    103 previous assembly Bmori_2016v1.0 (GCF_014905235.1) 3 NC_051360.1 (6972270..6976698, complement)

    Chromosome 3 - NC_085109.1Genomic Context describing neighboring genes Neighboring gene arylphorin subunit beta Neighboring gene hexamerin-1.1 Neighboring gene Troponin C at 25D Neighboring gene protein gooseberry-neuro Neighboring gene acidic juvenile hormone-suppressible protein 1 Neighboring gene acidic juvenile hormone-suppressible protein 1-like Neighboring gene Sp3 transcription factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Lysine acetylation stabilizes SP2 protein in the silkworm Bombyx mori. Zhou Y, et al. J Insect Physiol, 2016 Aug-Sep. PMID 27374983
    2. Gene analysis of an antiviral protein SP-2 from Chinese wild silkworm, Bombyx mandarina Moore and its bioactivity assay. Yao H, et al. Sci China C Life Sci, 2008 Oct. PMID 18815751
    3. Phylogenetic relationship of silkmoths inferred from sequence data of the arylphorin gene. Shimada T, et al. Mol Phylogenet Evol, 1995 Sep. PMID 8845960
    4. Structure of the gene for the arylphorin-type storage protein SP 2 of Bombyx mori. Fujii T, et al. J Biol Chem, 1989 Jul 5. PMID 2544581
    5. Crystallographic identification of an unexpected protein complex in silkworm haemolymph. Pietrzyk AJ, et al. Acta Crystallogr D Biol Crystallogr, 2013 Dec. PMID 24311577

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SP2 is a major nutrient storage protein from hemolymph for amino acid storage and utilization. Crosstalk between lysine acetylation and ubiquitination of SP2 might imply an important role of lysine acetylation for nutrient storage and utilization in silkworm.
      Title: Lysine acetylation stabilizes SP2 protein in the silkworm Bombyx mori.
    2. These studies revealed that SP2 and SP3 exist in the silkworm body as a heterohexamer formed by one SP2 trimer and one SP3 trimer.
      Title: Crystallographic identification of an unexpected protein complex in silkworm haemolymph.
    3. cDNA encoding an antiviral protein SP-2 against BmNPV was cloned from the midgut of Chinese wild silkworm
      Title: Gene analysis of an antiviral protein SP-2 from Chinese wild silkworm, Bombyx mandarina Moore and its bioactivity assay.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    sex-specific storage-protein 2
    Names
    SP 2
    arylphorin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044125.1 → NP_001037590.1  sex-specific storage-protein 2 precursor

      See identical proteins and their annotated locations for NP_001037590.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ443358
      UniProtKB/Swiss-Prot
      P20613, Q9TYA2
      UniProtKB/TrEMBL
      Q1HPP4
      Conserved Domains (3) summary
      pfam00372
      Location:161 → 437
      Hemocyanin_M; Hemocyanin, copper containing domain
      pfam03722
      Location:34 → 156
      Hemocyanin_N; Hemocyanin, all-alpha domain
      pfam03723
      Location:447 → 678
      Hemocyanin_C; Hemocyanin, ig-like domain

    RefSeqs of Annotated Genomes: GCF_030269925.1-RS_2024_01

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM3026992v2 Primary Assembly

    Genomic

    1. NC_085109.1 Reference ASM3026992v2 Primary Assembly

      Range
      6988477..6992905 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P20613.2 GenPept UniProtKB/Swiss-Prot:P20613

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