PRND prion like protein doppel [Equus caballus (horse)] - Gene

Summary

Official Symbol: PRNDprovided by VGNC
Official Full Name: prion like protein doppelprovided by VGNC
Primary source: VGNC:VGNC:21867
See related: Ensembl:ENSECAG00000004704
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Equus caballus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs: human all
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Genomic context

Location:: chromosome: 22

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	EquCab3.0 (GCF_002863925.1)	22	NC_009165.3 (18748021..18753556, complement)

Chromosome 22 - NC_009165.3 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:: NC_009165.3 Chromosome 22 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Absence of Strong Genetic Linkage Disequilibrium between Single Nucleotide Polymorphisms (SNPs) in the Prion Protein Gene (PRNP) and the Prion-Like Protein Gene (PRND) in the Horse, a Prion-Resistant Species.
Title: Absence of Strong Genetic Linkage Disequilibrium between Single Nucleotide Polymorphisms (SNPs) in the Prion Protein Gene (PRNP) and the Prion-Like Protein Gene (PRND) in the Horse, a Prion-Resistant Species.
Polymorphisms of the PRND gene were not detected. The authors conducted a comparative analysis of the amino acid sequences of the PRND gene to identify the differences between horses and other species. The amino acid sequence of the horse PRND gene showed the highest identity to that of sheep (83.7%), followed by that of goats, cattle and humans.
Title: No polymorphisms in the coding region of the prion-like protein gene in Thoroughbred racehorses.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables copper ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in intracellular copper ion homeostasis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein homooligomerization	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: prion-like protein doppel

Names: prion protein 2 (dublet)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.