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    GHR growth hormone receptor [ Balaenoptera acutorostrata (minke whale) ]

    Gene ID: 103002001, updated on 10-Oct-2024

    Summary

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    Gene symbol
    GHR
    Gene description
    growth hormone receptor
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Balaenoptera acutorostrata
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti; Balaenopteridae; Balaenoptera
    Orthologs
    human mouse all
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    Genomic context

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    See GHR in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2023_06 current mBalAcu1.1 (GCF_949987535.1) 2 NC_080065.1 (38513203..38793527)
    101 previous assembly BalAcu1.0 (GCF_000493695.1) Unplaced Scaffold NW_006733234.1 (3327185..3609935)

    Chromosome 2 - NC_080065.1Genomic Context describing neighboring genes Neighboring gene cytochrome c-like Neighboring gene uncharacterized LOC130707283 Neighboring gene CCAAT/enhancer-binding protein gamma-like Neighboring gene coiled-coil domain containing 152

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cytokine binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables growth factor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables growth hormone receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables peptide hormone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in growth hormone receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of peptidyl-tyrosine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of receptor signaling pathway via JAK-STAT IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of growth hormone receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    growth hormone receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_949987535.1-RS_2023_06

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mBalAcu1.1

    Genomic

    1. NC_080065.1 Reference mBalAcu1.1

      Range
      38513203..38793527
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_007195531.2 → XP_007195593.1  growth hormone receptor isoform X2

      See identical proteins and their annotated locations for XP_007195593.1

      UniProtKB/TrEMBL
      A0A384B7E2, A0A3Q8CKP0
      Conserved Domains (3) summary
      cd00063
      Location:149 → 250
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12772
      Location:316 → 618
      GHBP; Growth hormone receptor binding
      cl21522
      Location:49 → 127
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

    2. XM_057540022.1 → XP_057396005.1  growth hormone receptor isoform X2

      UniProtKB/TrEMBL
      A0A384B7E2

    3. XM_057540024.1 → XP_057396007.1  growth hormone receptor isoform X2

      UniProtKB/TrEMBL
      A0A384B7E2

    4. XM_057540023.1 → XP_057396006.1  growth hormone receptor isoform X2

      UniProtKB/TrEMBL
      A0A384B7E2

    5. XM_007195532.2 → XP_007195594.1  growth hormone receptor isoform X2

      See identical proteins and their annotated locations for XP_007195594.1

      UniProtKB/TrEMBL
      A0A384B7E2, A0A3Q8CKP0
      Conserved Domains (3) summary
      cd00063
      Location:149 → 250
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12772
      Location:316 → 618
      GHBP; Growth hormone receptor binding
      cl21522
      Location:49 → 127
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

    6. XM_007195530.2 → XP_007195592.1  growth hormone receptor isoform X1

      UniProtKB/TrEMBL
      A0A384B7F7, A0A3Q8CKP0
      Conserved Domains (3) summary
      cd00063
      Location:156 → 257
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12772
      Location:323 → 625
      GHBP; Growth hormone receptor binding
      cl21522
      Location:56 → 134
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    Nucleotide Protein
    Heading Accession and Version

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