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    RNF14 ring finger protein 14 [ Pongo abelii (Sumatran orangutan) ]

    Gene ID: 100172822, updated on 26-Mar-2024

    Summary

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    Gene symbol
    RNF14
    Gene description
    ring finger protein 14
    Locus tag
    CR201_G0017331
    See related
    Ensembl:ENSPPYG00000015894
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pongo abelii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
    Orthologs
    human mouse all
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    Genomic context

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    See RNF14 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 4 NC_071989.2 (150332661..150356834)
    RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 5 NC_071990.1 (150370803..150394969)

    Chromosome 4 - NC_071989.2Genomic Context describing neighboring genes Neighboring gene glycine cleavage system H protein, mitochondrial-like Neighboring gene DAP3 binding cell death enhancer 1 Neighboring gene protocadherin 12 Neighboring gene glucosamine-6-phosphate deaminase 1 Neighboring gene large ribosomal subunit protein uL11m-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • DKFZp459A2228

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin conjugating enzyme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase RNF14
    NP_001125890.1
    XP_009239405.1
    XP_009239406.1
    XP_054411045.1
    XP_054411046.1
    XP_054411047.1
    XP_054411048.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001132418.1 → NP_001125890.1  E3 ubiquitin-protein ligase RNF14

      See identical proteins and their annotated locations for NP_001125890.1

      Status: PROVISIONAL

      Source sequence(s)
      CR859336
      UniProtKB/TrEMBL
      Q5R9P7
      Related
      ENSPPYP00000017778.2, ENSPPYT00000018493.3
      Conserved Domains (4) summary
      smart00647
      Location:289 → 350
      IBR; In Between Ring fingers
      pfam01485
      Location:377 → 433
      IBR; IBR domain, a half RING-finger domain
      pfam05773
      Location:4 → 133
      RWD; RWD domain
      pfam14634
      Location:220 → 255
      zf-RING_5; zinc-RING finger domain

    RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Genomic

    1. NC_071989.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

      Range
      150332661..150356834
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054555070.2 → XP_054411045.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      UniProtKB/TrEMBL
      A0A2J8VNZ2, A0A6D2Y3S5, H2PGW9

    2. XM_054555071.2 → XP_054411046.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      UniProtKB/TrEMBL
      A0A2J8VNZ2, A0A6D2Y3S5, H2PGW9

    3. XM_009241131.2 → XP_009239406.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      See identical proteins and their annotated locations for XP_009239406.1

      UniProtKB/TrEMBL
      A0A2J8VNZ2, A0A6D2Y3S5, H2PGW9
      Conserved Domains (4) summary
      smart00647
      Location:289 → 350
      IBR; In Between Ring fingers
      pfam01485
      Location:377 → 433
      IBR; IBR domain, a half RING-finger domain
      pfam05773
      Location:7 → 133
      RWD; RWD domain
      cd16628
      Location:218 → 271
      RING-HC_RBR_RNF14; RING finger, HC subclass, found in RING finger protein 14 (RNF14) and similar proteins

    4. XM_009241130.3 → XP_009239405.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      See identical proteins and their annotated locations for XP_009239405.1

      UniProtKB/TrEMBL
      A0A2J8VNZ2, A0A6D2Y3S5, H2PGW9
      Conserved Domains (4) summary
      smart00647
      Location:289 → 350
      IBR; In Between Ring fingers
      pfam01485
      Location:377 → 433
      IBR; IBR domain, a half RING-finger domain
      pfam05773
      Location:7 → 133
      RWD; RWD domain
      cd16628
      Location:218 → 271
      RING-HC_RBR_RNF14; RING finger, HC subclass, found in RING finger protein 14 (RNF14) and similar proteins

    5. XM_054555073.1 → XP_054411048.1  E3 ubiquitin-protein ligase RNF14 isoform X2

      UniProtKB/TrEMBL
      A0A2J8VNZ4

    6. XM_054555072.1 → XP_054411047.1  E3 ubiquitin-protein ligase RNF14 isoform X2

      UniProtKB/TrEMBL
      A0A2J8VNZ4
    Nucleotide Protein
    Heading Accession and Version

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