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    ptk2 protein tyrosine kinase 2 [ Oryzias latipes (Japanese medaka) ]

    Gene ID: 101155713, updated on 9-Nov-2023

    Summary

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    Gene symbol
    ptk2
    Gene description
    protein tyrosine kinase 2
    See related
    EnsemblRapid:ENSORLG00000004751
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryzias latipes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae; Oryzias
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    Genomic context

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    See ptk2 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    39
    Annotation release Status Assembly Chr Location
    103 current ASM223467v1 (GCF_002234675.1) 16 NC_019874.2 (10381960..10450902, complement)
    102 previous assembly ASM31367v1 (GCF_000313675.1) 16 NC_019874.1 (6504958..6573864, complement)

    Chromosome 16 - NC_019874.2Genomic Context describing neighboring genes Neighboring gene magnesium transporter MRS2 Neighboring gene CLPTM1 like Neighboring gene protein NDRG1 Neighboring gene protein tyrosine phosphatase type IVA 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    focal adhesion kinase 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Oryzias latipes Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM223467v1 Primary Assembly

    Genomic

    1. NC_019874.2 Reference ASM223467v1 Primary Assembly

      Range
      10381960..10450902 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023964516.1 → XP_023820284.1  focal adhesion kinase 1 isoform X11

      UniProtKB/TrEMBL
      A0A3B3HI75
      Related
      ENSORLP00000005978.3, ENSORLT00000005979.3
      Conserved Domains (4) summary
      cd05056
      Location:449 → 718
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:50 → 272
      B41; Band 4.1 homologues
      cd13190
      Location:268 → 376
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:1091 → 1220
      Focal_AT; Focal adhesion targeting region

    2. XM_023964515.1 → XP_023820283.1  focal adhesion kinase 1 isoform X11

      UniProtKB/TrEMBL
      A0A3B3HI75
      Conserved Domains (4) summary
      cd05056
      Location:449 → 718
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:50 → 272
      B41; Band 4.1 homologues
      cd13190
      Location:268 → 376
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:1091 → 1220
      Focal_AT; Focal adhesion targeting region

    3. XM_023964507.1 → XP_023820275.1  focal adhesion kinase 1 isoform X3

      UniProtKB/TrEMBL
      A0A3B3I4L7
      Conserved Domains (4) summary
      cd05056
      Location:485 → 754
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:86 → 308
      B41; Band 4.1 homologues
      cd13190
      Location:304 → 412
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:1127 → 1256
      Focal_AT; Focal adhesion targeting region

    4. XM_023964509.1 → XP_023820277.1  focal adhesion kinase 1 isoform X5

      UniProtKB/TrEMBL
      A0A3B3HI75
      Conserved Domains (4) summary
      cd05056
      Location:488 → 757
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:89 → 311
      B41; Band 4.1 homologues
      cd13190
      Location:307 → 415
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:1126 → 1255
      Focal_AT; Focal adhesion targeting region

    5. XM_023964517.1 → XP_023820285.1  focal adhesion kinase 1 isoform X12

      UniProtKB/TrEMBL
      A0A3B3IP67
      Conserved Domains (4) summary
      cd05056
      Location:488 → 757
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:89 → 311
      B41; Band 4.1 homologues
      cd13190
      Location:307 → 415
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:1088 → 1217
      Focal_AT; Focal adhesion targeting region

    6. XM_023964508.1 → XP_023820276.1  focal adhesion kinase 1 isoform X4

      UniProtKB/TrEMBL
      A0A3B3HI75
      Conserved Domains (4) summary
      cd05056
      Location:488 → 757
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:89 → 311
      B41; Band 4.1 homologues
      cd13190
      Location:307 → 415
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:1127 → 1256
      Focal_AT; Focal adhesion targeting region

    7. XM_023964505.1 → XP_023820273.1  focal adhesion kinase 1 isoform X1

      UniProtKB/TrEMBL
      A0A3B3HI75
      Conserved Domains (4) summary
      cd05056
      Location:488 → 757
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:89 → 311
      B41; Band 4.1 homologues
      cd13190
      Location:307 → 415
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:1130 → 1259
      Focal_AT; Focal adhesion targeting region

    8. XM_023964506.1 → XP_023820274.1  focal adhesion kinase 1 isoform X2

      UniProtKB/TrEMBL
      A0A3B3HI75
      Conserved Domains (4) summary
      cd05056
      Location:487 → 756
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:89 → 311
      B41; Band 4.1 homologues
      cd13190
      Location:307 → 414
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:1129 → 1258
      Focal_AT; Focal adhesion targeting region

    9. XM_023964512.1 → XP_023820280.1  focal adhesion kinase 1 isoform X8

      UniProtKB/TrEMBL
      H2LIZ5
      Conserved Domains (4) summary
      cd05056
      Location:475 → 744
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:89 → 311
      B41; Band 4.1 homologues
      cd13190
      Location:307 → 415
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:1117 → 1246
      Focal_AT; Focal adhesion targeting region

    10. XM_023964510.1 → XP_023820278.1  focal adhesion kinase 1 isoform X6

      UniProtKB/TrEMBL
      A0A3B3HJF9
      Conserved Domains (4) summary
      cd05056
      Location:482 → 751
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:89 → 311
      B41; Band 4.1 homologues
      cd13190
      Location:307 → 415
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:1124 → 1253
      Focal_AT; Focal adhesion targeting region

    11. XM_023964511.1 → XP_023820279.1  focal adhesion kinase 1 isoform X7

      UniProtKB/TrEMBL
      A0A3B3IHW7
      Conserved Domains (4) summary
      cd05056
      Location:481 → 750
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:89 → 311
      B41; Band 4.1 homologues
      cd13190
      Location:307 → 415
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:1123 → 1252
      Focal_AT; Focal adhesion targeting region

    12. XM_023964514.1 → XP_023820282.1  focal adhesion kinase 1 isoform X10

      UniProtKB/TrEMBL
      A0A3B3HI75
      Conserved Domains (4) summary
      cd05056
      Location:488 → 757
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:89 → 311
      B41; Band 4.1 homologues
      cd13190
      Location:307 → 415
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:1106 → 1235
      Focal_AT; Focal adhesion targeting region

    13. XM_023964513.1 → XP_023820281.1  focal adhesion kinase 1 isoform X9

      UniProtKB/TrEMBL
      H2LIZ5
      Conserved Domains (4) summary
      cd05056
      Location:474 → 743
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:89 → 311
      B41; Band 4.1 homologues
      cd13190
      Location:307 → 414
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:1116 → 1245
      Focal_AT; Focal adhesion targeting region

    14. XM_023964528.1 → XP_023820296.1  focal adhesion kinase 1 isoform X22

      UniProtKB/TrEMBL
      A0A3B3HI75
      Conserved Domains (4) summary
      cd05056
      Location:487 → 756
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:89 → 311
      B41; Band 4.1 homologues
      cd13190
      Location:307 → 414
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:999 → 1128
      Focal_AT; Focal adhesion targeting region

    15. XM_023964520.1 → XP_023820288.1  focal adhesion kinase 1 isoform X15

      UniProtKB/TrEMBL
      A0A3B3HJF9
      Conserved Domains (4) summary
      cd05056
      Location:482 → 751
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:89 → 311
      B41; Band 4.1 homologues
      cd13190
      Location:307 → 415
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:997 → 1126
      Focal_AT; Focal adhesion targeting region

    16. XM_023964522.1 → XP_023820290.1  focal adhesion kinase 1 isoform X17

      UniProtKB/TrEMBL
      A0A3B3IHW7
      Conserved Domains (4) summary
      cd05056
      Location:481 → 750
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:89 → 311
      B41; Band 4.1 homologues
      cd13190
      Location:307 → 415
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:996 → 1125
      Focal_AT; Focal adhesion targeting region

    17. XM_023964518.1 → XP_023820286.1  focal adhesion kinase 1 isoform X13

      UniProtKB/TrEMBL
      A0A3B3HI75
      Conserved Domains (4) summary
      cd05056
      Location:488 → 757
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:89 → 311
      B41; Band 4.1 homologues
      cd13190
      Location:307 → 415
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:1003 → 1132
      Focal_AT; Focal adhesion targeting region

    18. XM_023964529.1 → XP_023820297.1  focal adhesion kinase 1 isoform X23

      UniProtKB/TrEMBL
      A0A3B3IHW7
      Conserved Domains (4) summary
      cd05056
      Location:480 → 749
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:89 → 311
      B41; Band 4.1 homologues
      cd13190
      Location:307 → 414
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:992 → 1121
      Focal_AT; Focal adhesion targeting region

    19. XM_023964519.1 → XP_023820287.1  focal adhesion kinase 1 isoform X14

      UniProtKB/TrEMBL
      A0A3B3HI75
      Conserved Domains (4) summary
      cd05056
      Location:487 → 756
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:89 → 311
      B41; Band 4.1 homologues
      cd13190
      Location:307 → 414
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:1002 → 1131
      Focal_AT; Focal adhesion targeting region

    20. XM_023964525.1 → XP_023820293.1  focal adhesion kinase 1 isoform X19

      UniProtKB/TrEMBL
      H2LIZ5
      Conserved Domains (4) summary
      cd05056
      Location:475 → 744
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:89 → 311
      B41; Band 4.1 homologues
      cd13190
      Location:307 → 415
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:990 → 1119
      Focal_AT; Focal adhesion targeting region

    21. XM_023964527.1 → XP_023820295.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      H2LIZ5
      Related
      ENSORLP00000031387.2, ENSORLT00000031828.2
      Conserved Domains (4) summary
      cd05056
      Location:474 → 743
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:89 → 311
      B41; Band 4.1 homologues
      cd13190
      Location:307 → 414
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:986 → 1115
      Focal_AT; Focal adhesion targeting region

    22. XM_023964521.1 → XP_023820289.1  focal adhesion kinase 1 isoform X16

      UniProtKB/TrEMBL
      A0A3B3HJF9
      Related
      ENSORLP00000031879.2, ENSORLT00000028232.2
      Conserved Domains (4) summary
      cd05056
      Location:481 → 750
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:89 → 311
      B41; Band 4.1 homologues
      cd13190
      Location:307 → 414
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:996 → 1125
      Focal_AT; Focal adhesion targeting region

    23. XM_023964524.1 → XP_023820292.1  focal adhesion kinase 1 isoform X18

      UniProtKB/TrEMBL
      A0A3B3IHW7
      Related
      ENSORLP00000043516.2, ENSORLT00000031214.2
      Conserved Domains (4) summary
      cd05056
      Location:480 → 749
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:89 → 311
      B41; Band 4.1 homologues
      cd13190
      Location:307 → 414
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:995 → 1124
      Focal_AT; Focal adhesion targeting region

    24. XM_023964526.1 → XP_023820294.1  focal adhesion kinase 1 isoform X20

      UniProtKB/TrEMBL
      H2LIZ5
      Conserved Domains (4) summary
      cd05056
      Location:474 → 743
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:89 → 311
      B41; Band 4.1 homologues
      cd13190
      Location:307 → 414
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:989 → 1118
      Focal_AT; Focal adhesion targeting region
    Nucleotide Protein
    Heading Accession and Version

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