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    PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 [ Theropithecus gelada (gelada) ]

    Gene ID: 112626017, updated on 15-Mar-2024

    Summary

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    Gene symbol
    PRKAA1
    Gene description
    protein kinase AMP-activated catalytic subunit alpha 1
    See related
    Ensembl:ENSTGEG00000009736
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Theropithecus gelada
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Theropithecus
    Orthologs
    human mouse all
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    Genomic context

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    See PRKAA1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    100 current Tgel_1.0 (GCF_003255815.1) 6 NC_037673.1 (40371403..40409853, complement)

    Chromosome 6 - NC_037673.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112626986 Neighboring gene prostaglandin E receptor 4 Neighboring gene tetratricopeptide repeat domain 33 Neighboring gene uncharacterized LOC112626019 Neighboring gene small nucleolar RNA SNORA57 Neighboring gene small nucleolar RNA SNORD72 Neighboring gene ATP synthase subunit f, mitochondrial-like Neighboring gene ribosomal protein L37

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037673.1 Chromosome 6 Reference Tgel_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables AMP-activated protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    5'-AMP-activated protein kinase catalytic subunit alpha-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Theropithecus gelada Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Tgel_1.0 Primary Assembly

    Genomic

    1. NC_037673.1 Reference Tgel_1.0 Primary Assembly

      Range
      40371403..40409853 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025387699.1 → XP_025243484.1  5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X1

      UniProtKB/TrEMBL
      A0A8D2EV05
      Related
      ENSTGEP00000011946.1, ENSTGET00000014367.1
      Conserved Domains (3) summary
      cd12199
      Location:490 → 643
      AMPKA1_C; C-terminal regulatory domain of 5'-AMP-activated protein kinase (AMPK) alpha 1 catalytic subunit
      cd14403
      Location:382 → 446
      UBA_AID_AAPK1; UBA-like autoinhibitory domain (AID) found in vertebrate 5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPKalpha-1)
      cd14079
      Location:95 → 365
      STKc_AMPK_alpha; Catalytic domain of the Alpha subunit of the Serine/Threonine Kinase, AMP-activated protein kinase

    2. XM_025387700.1 → XP_025243485.1  5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X2

      UniProtKB/TrEMBL
      A0A8D2EQ04, A0A8D2EV05
      Related
      ENSTGEP00000011944.1, ENSTGET00000014365.1
      Conserved Domains (3) summary
      cd12199
      Location:404 → 557
      AMPKA1_C; C-terminal regulatory domain of 5'-AMP-activated protein kinase (AMPK) alpha 1 catalytic subunit
      cd14403
      Location:296 → 360
      UBA_AID_AAPK1; UBA-like autoinhibitory domain (AID) found in vertebrate 5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPKalpha-1)
      cd14079
      Location:24 → 279
      STKc_AMPK_alpha; Catalytic domain of the Alpha subunit of the Serine/Threonine Kinase, AMP-activated protein kinase

    3. XM_025387701.1 → XP_025243486.1  5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X3

      UniProtKB/TrEMBL
      A0A8D2EXW9
      Related
      ENSTGEP00000011950.1, ENSTGET00000014371.1
      Conserved Domains (1) summary
      cl21453
      Location:24 → 199
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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