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    Uba2 ubiquitin like modifier activating enzyme 2 [ Urocitellus parryii (Arctic ground squirrel) ]

    Gene ID: 113184496, updated on 15-Mar-2024

    Summary

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    Gene symbol
    Uba2
    Gene description
    ubiquitin like modifier activating enzyme 2
    See related
    Ensembl:ENSUPAG00010010752
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Urocitellus parryii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae; Xerinae; Marmotini; Urocitellus
    Orthologs
    human mouse all
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    Genomic context

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    See Uba2 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    100 current ASM342692v1 (GCF_003426925.1) Unplaced Scaffold NW_020539974.1 (5075780..5122378)

    NW_020539974.1Genomic Context describing neighboring genes Neighboring gene glucose-6-phosphate isomerase Neighboring gene programmed cell death 2 like Neighboring gene U2 spliceosomal RNA Neighboring gene WT1 interacting protein Neighboring gene major allergen I polypeptide chain 1-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_020539974 Unplaced Scaffold Reference ASM342692v1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables SUMO activating enzyme activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein sumoylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SUMO activating enzyme complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SUMO-activating enzyme subunit 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Urocitellus parryii Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM342692v1

    Genomic

    1. NW_020539974.1 Reference ASM342692v1

      Range
      5075780..5122378
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_026391221.1 → XP_026247006.1  SUMO-activating enzyme subunit 2 isoform X2

      UniProtKB/TrEMBL
      A0A8D2HIQ1
      Conserved Domains (4) summary
      cd01489
      Location:99 → 522
      Uba2_SUMO; Ubiquitin activating enzyme (E1) subunit UBA2. UBA2 is part of the heterodimeric activating enzyme (E1), specific for the SUMO family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to ...
      pfam10585
      Location:259 → 440
      UBA_e1_thiolCys; Ubiquitin-activating enzyme active site
      pfam14732
      Location:530 → 616
      UAE_UbL; Ubiquitin/SUMO-activating enzyme ubiquitin-like domain
      pfam16195
      Location:627 → 713
      UBA2_C; SUMO-activating enzyme subunit 2 C-terminus

    2. XM_026391220.1 → XP_026247005.1  SUMO-activating enzyme subunit 2 isoform X1

      UniProtKB/TrEMBL
      A0A8D2HIQ1
      Related
      ENSUPAP00010013302.1, ENSUPAT00010015244.1
      Conserved Domains (3) summary
      cd01489
      Location:99 → 524
      Uba2_SUMO; Ubiquitin activating enzyme (E1) subunit UBA2. UBA2 is part of the heterodimeric activating enzyme (E1), specific for the SUMO family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to ...
      pfam14732
      Location:532 → 618
      UAE_UbL; Ubiquitin/SUMO-activating enzyme ubiquitin-like domain
      pfam16195
      Location:629 → 715
      UBA2_C; SUMO-activating enzyme subunit 2 C-terminus
    Nucleotide Protein
    Heading Accession and Version

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