C1ql3 complement C1q like 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: C1ql3provided by RGD
Official Full Name: complement C1q like 3provided by RGD
Primary source: RGD:1591795
See related: EnsemblRapid:ENSRNOG00000017459 AllianceGenome:RGD:1591795
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Adij
Summary: Predicted to enable identical protein binding activity. Predicted to be involved in neurotransmitter receptor localization to postsynaptic specialization membrane and postsynaptic density assembly. Predicted to act upstream of or within regulation of synapse organization. Predicted to be located in extracellular region. Predicted to be active in glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; and synaptic cleft. Orthologous to human C1QL3 (complement C1q like 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Brain (RPKM 78.1), Kidney (RPKM 20.8) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 17q12.3

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	17	NC_086035.1 (81028418..81038244, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	17	NC_051352.1 (76119344..76129170, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	17	NC_005116.4 (80314186..80320681, complement)

Chromosome 17 - NC_086035.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

CTRP13 attenuates the expression of LN and CAV-1 Induced by high glucose via CaMKKbeta/AMPK pathway in rLSECs.
Title: CTRP13 attenuates the expression of LN and CAV-1 Induced by high glucose via CaMKKβ/AMPK pathway in rLSECs.

Submit: New GeneRIF Correction

General gene information

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Markers

RH143521 (e-PCR)
- UniSTS:232767

C1ql3 (e-PCR), detects polymorphism
- UniSTS:531288

AA964004 (e-PCR)
- UniSTS:248413

C1ql3 (e-PCR), detects polymorphism
- UniSTS:531053

RH142802 (e-PCR)
- UniSTS:232049

AI790318 (e-PCR)
- UniSTS:178571

AA893351 (e-PCR)
- UniSTS:243376

RH143658 (e-PCR)
- UniSTS:232904

AI233834 (e-PCR)
- UniSTS:250312

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables identical protein binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in neurotransmitter receptor localization to postsynaptic specialization membrane	ISO Inferred from Sequence Orthology more info
involved_in postsynaptic density assembly	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of synapse organization	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in extracellular region	ISO Inferred from Sequence Orthology more info
is_active_in glutamatergic synapse	ISO Inferred from Sequence Orthology more info
is_active_in hippocampal mossy fiber to CA3 synapse	ISO Inferred from Sequence Orthology more info
is_active_in synaptic cleft	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: complement C1q-like protein 3

Names: adiponectin j; complement component 1, q subcomponent-like 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.