U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    AP3 K-box region and MADS-box transcription factor family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824601, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    AP3
    Official Full Name
    K-box region and MADS-box transcription factor family protein
    Primary source
    TAIR:AT3G54340
    Locus tag
    AT3G54340
    See related
    Araport:AT3G54340
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    APETALA 3; ATAP3; FLORAL HOMEOTIC PROTEIN APETALA 3
    Summary
    Floral homeotic gene encoding a MADS domain protein homologous to SRF transcription factors. Specifies petal and stamen identities. Associates with PISTILLATA.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See AP3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Sequence:
    Chromosome: 3; NC_003074.8 (20119140..20121314, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene DNA-directed RNA polymerase subunit alpha Neighboring gene Integrase-type DNA-binding superfamily protein Neighboring gene Forkhead-associated (FHA) domain-containing protein Neighboring gene zinc ion binding protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Exogenous Promoter Triggers APETALA3 Silencing through RNA-Directed DNA Methylation Pathway in Arabidopsis. Wang B, et al. Int J Mol Sci, 2019 Sep 11. PMID 31514282, Free PMC Article
    2. Ectopic expression of FaesAP3, a Fagopyrum esculentum (Polygonaceae) AP3 orthologous gene rescues stamen development in an Arabidopsis ap3 mutant. Fang ZW, et al. Gene, 2014 Oct 25. PMID 25149019
    3. Conifer reproductive development involves B-type MADS-box genes with distinct and different activities in male organ primordia. Sundström J, et al. Plant J, 2002 Jul. PMID 12121446
    4. The C-terminal sequence of LMADS1 is essential for the formation of homodimers for B function proteins. Tzeng TY, et al. J Biol Chem, 2004 Mar 12. PMID 14676188
    5. My favourite flowering image: an Arabidopsis inflorescence expressing fluorescent reporters for the APETALA3 and SUPERMAN genes. Prunet N. J Exp Bot, 2019 Nov 18. PMID 29659996, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. My favourite flowering image: an Arabidopsis inflorescence expressing fluorescent reporters for the APETALA3 and SUPERMAN genes.
      Title: My favourite flowering image: an Arabidopsis inflorescence expressing fluorescent reporters for the APETALA3 and SUPERMAN genes.
    2. The expression of AP3 was reactivated and the methylation level of AP3 promoter was also reduced in RNA-Directed DNA Methylation-defective AP3-silencing lines.
      Title: Exogenous Promoter Triggers APETALA3 Silencing through RNA-Directed DNA Methylation Pathway in Arabidopsis.
    3. Ectopic Fagopyrum esculentum AP3 can rescue stamen development in Arabidopsis ap3 mutant.
      Title: Ectopic expression of FaesAP3, a Fagopyrum esculentum (Polygonaceae) AP3 orthologous gene rescues stamen development in an Arabidopsis ap3 mutant.
    4. Data indicate that C function regulator AGAMOUS and the B function regulators APETALA3 and PISTILLATA control many developmental processes in conjunction, as well as independent activities.
      Title: Control of reproductive floral organ identity specification in Arabidopsis by the C function regulator AGAMOUS.
    5. These results imply considerable changes in the composition and topology of the gene network controlled by AP3/PI during the course of flower development.
      Title: Molecular basis for the specification of floral organs by APETALA3 and PISTILLATA.
    6. BNQ genes Are negatively regulated by AP3 and PI in petals.
      Title: The Arabidopsis floral homeotic proteins APETALA3 and PISTILLATA negatively regulate the BANQUO genes implicated in light signaling.
    7. truncated form, lacking the conserved C-terminal motifs, functions to direct floral organ identity specification
      Title: Conserved C-terminal motifs of the Arabidopsis proteins APETALA3 and PISTILLATA are dispensable for floral organ identity function.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_115294.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within specification of floral organ identity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in specification of floral organ identity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    K-box region and MADS-box transcription factor family protein
    NP_191002.1
    • APETALA 3 (AP3); CONTAINS InterPro DOMAIN/s: Transcription factor, MADS-box (InterPro:IPR002100), Transcription factor, K-box (InterPro:IPR002487); BEST Arabidopsis thaliana protein match is: AGAMOUS-like 71 (TAIR:AT5G51870.1); Has 6838 Blast hits to 6837 proteins in 855 species: Archae - 0; Bacteria - 0; Metazoa - 626; Fungi - 302; Plants - 5820; Viruses - 0; Other Eukaryotes - 90 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      20119140..20121314 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115294.6 → NP_191002.1  K-box region and MADS-box transcription factor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191002.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P35632, Q39003, Q8LB79, Q9S7Q3, Q9SQ14, Q9SQ15, Q9SQ16, Q9SQ17, Q9SQ18, Q9SQ19, Q9SQ20, Q9SQ21, Q9SQ22, Q9SX13
      UniProtKB/TrEMBL
      A0A178VHZ2, A0A5S9XL06, A0A7G2ESU4
      Conserved Domains (2) summary
      cd00265
      Location:2 → 80
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam01486
      Location:81 → 169
      K-box; K-box region
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P35632.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools