U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    PNLIP pancreatic lipase [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100009157, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    PNLIP
    Gene description
    pancreatic lipase
    See related
    Ensembl:ENSOCUG00000029602
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Also known as
    PTL; PNLIPRP2
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PNLIP in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 18 NC_067391.1 (61007515..61026263)

    Chromosome 18 - NC_067391.1Genomic Context describing neighboring genes Neighboring gene pancreatic triacylglycerol lipase Neighboring gene uncharacterized LOC103351432 Neighboring gene pancreatic triacylglycerol lipase-like Neighboring gene pancreatic lipase related protein 1 Neighboring gene uncharacterized LOC127484302

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_067391.1 Chromosome 18 Reference UM_NZW_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Molecular cloning and characterization of rabbit pancreatic triglyceride lipase. Aleman-Gomez JA, et al. Biochem Biophys Res Commun, 1992 Nov 16. PMID 1445366

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables triacylglycerol lipase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    pancreatic triacylglycerol lipase
    Names
    PL
    triglyceride lipase
    NP_001075786.1
    XP_008268675.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082317.1 → NP_001075786.1  pancreatic triacylglycerol lipase precursor

      See identical proteins and their annotated locations for NP_001075786.1

      Status: PROVISIONAL

      Source sequence(s)
      M99365
      UniProtKB/Swiss-Prot
      Q02157
      UniProtKB/TrEMBL
      A0A5F9C5N6
      Related
      ENSOCUP00000012518.4, ENSOCUT00000014561.4
      Conserved Domains (3) summary
      cd00707
      Location:52 → 348
      Pancreat_lipase_like; Pancreatic lipase-like enzymes. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the ...
      cd01759
      Location:355 → 465
      PLAT_PL; PLAT/LH2 domain of pancreatic triglyceride lipase. Lipases hydrolyze phospholipids and triglycerides to generate fatty acids for energy production or for storage and to release inositol phosphates that act as second messengers. The central role of ...
      pfam00151
      Location:18 → 352
      Lipase; Lipase

    RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UM_NZW_1.0 Primary Assembly

    Genomic

    1. NC_067391.1 Reference UM_NZW_1.0 Primary Assembly

      Range
      61007515..61026263
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008270453.3 → XP_008268675.1  pancreatic triacylglycerol lipase isoform X1

      UniProtKB/TrEMBL
      A0A5F9C5N6, G1T7N2
      Conserved Domains (3) summary
      cd00707
      Location:51 → 348
      Pancreat_lipase_like; Pancreatic lipase-like enzymes. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the ...
      cd01759
      Location:355 → 465
      PLAT_PL; PLAT/LH2 domain of pancreatic triglyceride lipase. Lipases hydrolyze phospholipids and triglycerides to generate fatty acids for energy production or for storage and to release inositol phosphates that act as second messengers. The central role of ...
      pfam00151
      Location:18 → 352
      Lipase; Lipase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q02157.1 GenPept UniProtKB/Swiss-Prot:Q02157

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.