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    EPRS1 glutamyl-prolyl-tRNA synthetase 1 [ Mirounga leonina (Southern elephant seal) ]

    Gene ID: 118014081, updated on 20-Mar-2024

    Summary

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    Gene symbol
    EPRS1
    Gene description
    glutamyl-prolyl-tRNA synthetase 1
    Locus tag
    GH733_010551
    See related
    EnsemblRapid:ENSMLOG00005006208
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Mirounga leonina
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae; Mirounga
    Orthologs
    human mouse all
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    Genomic context

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    See EPRS1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    100 current KU_Mleo_1.0 (GCF_011800145.1) Unplaced Scaffold NW_023270389.1 (11926400..11993784)

    NW_023270389.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S15a-like Neighboring gene isoleucyl-tRNA synthetase 2, mitochondrial Neighboring gene 3'(2'), 5'-bisphosphate nucleotidase 1 Neighboring gene solute carrier family 30 member 10 Neighboring gene lysophospholipase like 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_023270389 Unplaced Scaffold Reference KU_Mleo_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables glutamate-tRNA ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables proline-tRNA ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glutamyl-tRNA aminoacylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in prolyl-tRNA aminoacylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of aminoacyl-tRNA synthetase multienzyme complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    bifunctional glutamate/proline--tRNA ligase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Mirounga leonina Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference KU_Mleo_1.0 Primary Assembly

    Genomic

    1. NW_023270389.1 Reference KU_Mleo_1.0 Primary Assembly

      Range
      11926400..11993784
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_035010106.1 → XP_034865997.1  bifunctional glutamate/proline--tRNA ligase

      Related
      ENSMLOP00005008899.1, ENSMLOT00005010096.1
      Conserved Domains (4) summary
      PLN02907
      Location:13 → 711
      PLN02907; glutamate-tRNA ligase
      PRK08661
      Location:1016 → 1509
      PRK08661; prolyl-tRNA synthetase; Provisional
      cd00936
      Location:753 → 802
      WEPRS_RNA; WEPRS_RNA binding domain. This short RNA-binding domain is found in several higher eukaryote aminoacyl-tRNA synthetases (aaRSs). It is found in multiple copies in eukaryotic bifunctional glutamyl-prolyl-tRNA synthetases (EPRS) in a region that separates ...
      pfam00458
      Location:901 → 949
      WHEP-TRS; WHEP-TRS domain
    Nucleotide Protein
    Heading Accession and Version

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