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    LOC115454698 aminopeptidase N [ Manduca sexta (tobacco hornworm) ]

    Gene ID: 115454698, updated on 14-Dec-2023

    Summary

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    Gene symbol
    LOC115454698
    Gene description
    aminopeptidase N
    Locus tag
    O3G_MSEX000347
    See related
    EnsemblRapid:ENSMSXG00000020094
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Manduca sexta
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea; Sphingidae; Sphinginae; Sphingini; Manduca
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    Genomic context

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    See LOC115454698 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    102 current JHU_Msex_v1.0 (GCF_014839805.1) 18 NC_051132.1 (1007561..1049490, complement)
    100 previous assembly Msex_1.0 (GCF_000262585.1) Unplaced Scaffold NW_021945544.1 (61..1918, complement)

    Chromosome 18 - NC_051132.1Genomic Context describing neighboring genes Neighboring gene protein Skeletor Neighboring gene EGF receptor activation regulator Star Neighboring gene actin cytoskeleton-regulatory complex protein pan-1 Neighboring gene cylicin-1 Neighboring gene nucleolar protein 12

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Integrated modeling of protein-coding genes in the Manduca sexta genome using RNA-Seq data from the biochemical model insect. Cao X, et al. Insect Biochem Mol Biol, 2015 Jul. PMID 25612938, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloaminopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables peptide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in peptide catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    aminopeptidase N

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Manduca sexta Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference JHU_Msex_v1.0 Primary Assembly

    Genomic

    1. NC_051132.1 Reference JHU_Msex_v1.0 Primary Assembly

      Range
      1007561..1049490 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_037440284.1 → XP_037296181.1  aminopeptidase N isoform X2

      Related
      ENSMSXP00000028935.1, ENSMSXT00000033218.1
      Conserved Domains (2) summary
      cd09601
      Location:38 → 506
      M1_APN-Q_like; Peptidase M1 aminopeptidase N catalytic domain family which includes aminopeptidase N (APN), aminopeptidase Q (APQ), tricorn interacting factor F3, and endoplasmic reticulum aminopeptidase 1 (ERAP1)
      pfam11838
      Location:587 → 918
      ERAP1_C; ERAP1-like C-terminal domain

    2. XM_037440285.1 → XP_037296182.1  aminopeptidase N isoform X3

      Related
      ENSMSXP00000028965.1, ENSMSXT00000033256.1
      Conserved Domains (2) summary
      cd09601
      Location:30 → 498
      M1_APN-Q_like; Peptidase M1 aminopeptidase N catalytic domain family which includes aminopeptidase N (APN), aminopeptidase Q (APQ), tricorn interacting factor F3, and endoplasmic reticulum aminopeptidase 1 (ERAP1)
      pfam11838
      Location:579 → 910
      ERAP1_C; ERAP1-like C-terminal domain

    3. XM_037440283.1 → XP_037296180.1  aminopeptidase N isoform X1

      Conserved Domains (2) summary
      cd09601
      Location:38 → 506
      M1_APN-Q_like; Peptidase M1 aminopeptidase N catalytic domain family which includes aminopeptidase N (APN), aminopeptidase Q (APQ), tricorn interacting factor F3, and endoplasmic reticulum aminopeptidase 1 (ERAP1)
      pfam11838
      Location:587 → 918
      ERAP1_C; ERAP1-like C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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