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    DVL1 dishevelled segment polarity protein 1 [ Chelonia mydas (Green sea turtle) ]

    Gene ID: 102940481, updated on 10-Mar-2024

    Summary

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    Gene symbol
    DVL1
    Gene description
    dishevelled segment polarity protein 1
    Locus tag
    UY3_16978
    See related
    EnsemblRapid:ENSCMYG00015010247
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Chelonia mydas
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Americhelydia; Chelonioidea; Cheloniidae; Chelonia
    Orthologs
    human mouse all
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    Genomic context

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    See DVL1 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    103 current rCheMyd1.pri.v2 (GCF_015237465.2) 18 NC_051258.2 (15827978..16007824, complement)
    102 previous assembly rCheMyd1.pri (GCF_015237465.1) 18 NC_051258.1 (7326709..7498593)

    Chromosome 18 - NC_051258.2Genomic Context describing neighboring genes Neighboring gene integrator complex subunit 11 Neighboring gene ceramide-1-phosphate transfer protein Neighboring gene taste 1 receptor member 3 Neighboring gene uncharacterized LOC119563932 Neighboring gene matrix remodeling associated 8 Neighboring gene aurora kinase A interacting protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables frizzled binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    segment polarity protein dishevelled homolog DVL-1
    Names
    Segment polarity protein dishevelled like protein DVL-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Chelonia mydas Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference rCheMyd1.pri.v2 Primary Assembly

    Genomic

    1. NC_051258.2 Reference rCheMyd1.pri.v2 Primary Assembly

      Range
      15827978..16007824 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_037880973.2 → XP_037736901.1  segment polarity protein dishevelled homolog DVL-1 isoform X4

      Conserved Domains (5) summary
      smart00021
      Location:1 → 85
      DAX; Domain present in Dishevelled and axin
      cd00992
      Location:252 → 339
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04438
      Location:394 → 477
      DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
      pfam02377
      Location:90 → 250
      Dishevelled; Dishevelled specific domain
      pfam12316
      Location:481 → 675
      Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal

    2. XM_037880972.2 → XP_037736900.1  segment polarity protein dishevelled homolog DVL-1 isoform X3

      Related
      ENSCMYP00015015827.1, ENSCMYT00015019222.1
      Conserved Domains (5) summary
      smart00021
      Location:1 → 85
      DAX; Domain present in Dishevelled and axin
      cd00992
      Location:252 → 339
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04438
      Location:418 → 501
      DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
      pfam02377
      Location:90 → 250
      Dishevelled; Dishevelled specific domain
      pfam12316
      Location:505 → 699
      Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal

    3. XM_037880971.2 → XP_037736899.1  segment polarity protein dishevelled homolog DVL-1 isoform X2

      Conserved Domains (5) summary
      cd00992
      Location:280 → 367
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04438
      Location:422 → 505
      DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
      pfam02377
      Location:118 → 278
      Dishevelled; Dishevelled specific domain
      pfam12316
      Location:509 → 703
      Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal
      cl02426
      Location:86 → 113
      DIX; DIX domain

    4. XM_037880970.2 → XP_037736898.1  segment polarity protein dishevelled homolog DVL-1 isoform X1

      Related
      ENSCMYP00015015822.1, ENSCMYT00015019217.1
      Conserved Domains (5) summary
      cd00992
      Location:280 → 367
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04438
      Location:446 → 529
      DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
      pfam02377
      Location:118 → 278
      Dishevelled; Dishevelled specific domain
      pfam12316
      Location:533 → 727
      Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal
      cl02426
      Location:86 → 113
      DIX; DIX domain

    5. XM_037880974.2 → XP_037736902.1  segment polarity protein dishevelled homolog DVL-1 isoform X5

      Related
      ENSCMYP00015015812.1, ENSCMYT00015019207.1
      Conserved Domains (5) summary
      cd00992
      Location:217 → 304
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04438
      Location:383 → 466
      DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
      pfam02377
      Location:55 → 215
      Dishevelled; Dishevelled specific domain
      pfam12316
      Location:470 → 664
      Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal
      cl02426
      Location:22 → 50
      DIX; DIX domain

    6. XM_043531702.1 → XP_043387637.1  segment polarity protein dishevelled homolog DVL-1 isoform X8

      Conserved Domains (2) summary
      cd00992
      Location:69 → 156
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04438
      Location:235 → 318
      DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...

    7. XM_043531701.1 → XP_043387636.1  segment polarity protein dishevelled homolog DVL-1 isoform X7

      Conserved Domains (2) summary
      cd00992
      Location:162 → 249
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04438
      Location:304 → 387
      DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...

    8. XM_037880975.2 → XP_037736903.1  segment polarity protein dishevelled homolog DVL-1 isoform X6

      Conserved Domains (4) summary
      cd00992
      Location:162 → 249
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04438
      Location:328 → 411
      DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
      pfam02377
      Location:67 → 160
      Dishevelled; Dishevelled specific domain
      pfam12316
      Location:415 → 609
      Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal

    RNA

    1. XR_006286435.1 RNA Sequence

    2. XR_006286434.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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