U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    ASB3 ankyrin repeat and SOCS box containing 3 [ Canis lupus familiaris (dog) ]

    Gene ID: 474592, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ASB3provided by VGNC
    Official Full Name
    ankyrin repeat and SOCS box containing 3provided by VGNC
    Primary source
    VGNC:VGNC:108201
    See related
    Ensembl:ENSCAFG00845007688
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ASB3 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 10 NC_051814.1 (55703328..55814197, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 10 NC_006592.4 (54664431..54738630, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 10 NC_049231.1 (55977514..56051739, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 10 NC_049270.1 (55404712..55478696, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 10 NC_049751.1 (55690487..55764686, complement)

    Chromosome 10 - NC_051814.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119873674 Neighboring gene dynein light chain 1, cytoplasmic-like Neighboring gene ChaC glutathione specific gamma-glutamylcyclotransferase 2 Neighboring gene endoplasmic reticulum lectin 1 Neighboring gene uncharacterized LOC119873778

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    ankyrin repeat and SOCS box protein 3

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205055.1 → NP_001191984.1  ankyrin repeat and SOCS box protein 3

      Status: VALIDATED

      Source sequence(s)
      JAAUVH010000358
      UniProtKB/TrEMBL
      A0A8C0PR50, A0A8I3N942, A0A8P0PFK3
      Related
      ENSCAFP00845010589.1, ENSCAFT00845013637.1
      Conserved Domains (4) summary
      cd00204
      Location:146 → 267
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd03722
      Location:458 → 508
      SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
      pfam12796
      Location:83 → 176
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:146 → 176
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051814.1 Reference ROS_Cfam_1.0

      Range
      55703328..55814197 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038678778.1 → XP_038534706.1  ankyrin repeat and SOCS box protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A8C0PR50, A0A8I3N905
      Related
      ENSCAFP00845010529.1, ENSCAFT00845013562.1
      Conserved Domains (4) summary
      cd03722
      Location:376 → 426
      SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
      sd00045
      Location:42 → 77
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:16 → 109
      Ank_2; Ankyrin repeats (3 copies)
      cl39094
      Location:197 → 303
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_038678779.1 → XP_038534707.1  ankyrin repeat and SOCS box protein 3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0PR50
      Conserved Domains (4) summary
      cd03722
      Location:373 → 423
      SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
      sd00045
      Location:147 → 177
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:217 → 310
      Ank_2; Ankyrin repeats (3 copies)
      cl39094
      Location:22 → 238
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_038678774.1 → XP_038534702.1  ankyrin repeat and SOCS box protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0PR50, A0A8C0SSW7, A0A8I3N6M8
      Related
      ENSCAFP00845010507.1, ENSCAFT00845013538.1
      Conserved Domains (4) summary
      cd03722
      Location:459 → 509
      SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
      sd00045
      Location:147 → 177
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:217 → 310
      Ank_2; Ankyrin repeats (3 copies)
      cl39094
      Location:22 → 238
      Ank_2; Ankyrin repeats (3 copies)

    4. XM_038678775.1 → XP_038534703.1  ankyrin repeat and SOCS box protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0PR50, A0A8C0SSW7, A0A8I3N6M8
      Conserved Domains (4) summary
      cd03722
      Location:459 → 509
      SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
      sd00045
      Location:147 → 177
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:217 → 310
      Ank_2; Ankyrin repeats (3 copies)
      cl39094
      Location:22 → 238
      Ank_2; Ankyrin repeats (3 copies)

    5. XM_038678777.1 → XP_038534705.1  ankyrin repeat and SOCS box protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0PR50, A0A8C0SSW7, A0A8I3N6M8
      Conserved Domains (4) summary
      cd03722
      Location:459 → 509
      SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
      sd00045
      Location:147 → 177
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:217 → 310
      Ank_2; Ankyrin repeats (3 copies)
      cl39094
      Location:22 → 238
      Ank_2; Ankyrin repeats (3 copies)

    6. XM_038678776.1 → XP_038534704.1  ankyrin repeat and SOCS box protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0PR50, A0A8C0SSW7, A0A8I3N6M8
      Conserved Domains (4) summary
      cd03722
      Location:459 → 509
      SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
      sd00045
      Location:147 → 177
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:217 → 310
      Ank_2; Ankyrin repeats (3 copies)
      cl39094
      Location:22 → 238
      Ank_2; Ankyrin repeats (3 copies)

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049270.1 Alternate UMICH_Zoey_3.1

      Range
      55404712..55478696 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049751.1 Alternate UNSW_CanFamBas_1.0

      Range
      55690487..55764686 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049231.1 Alternate UU_Cfam_GSD_1.0

      Range
      55977514..56051739 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006592.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      54664431..54738630 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials