U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 [ Ochotona curzoniae (black-lipped pika) ]

    Gene ID: 121155633, updated on 22-Mar-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    PIK3R1
    Gene description
    phosphoinositide-3-kinase regulatory subunit 1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ochotona curzoniae
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Ochotonidae; Ochotona
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PIK3R1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    100 current NIBS_Ocur_1.0 (GCF_017591425.1) Unplaced Scaffold NW_024465655.1 (1775735..1857468, complement)

    NW_024465655.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 30 member 5 Neighboring gene cyclin B1 Neighboring gene uncharacterized LOC121155634 Neighboring gene non-histone chromosomal protein HMG-14-like Neighboring gene melanoma inhibitory activity protein 2-like

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NW_024465655 Unplaced Scaffold Reference NIBS_Ocur_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol-3-kinase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in insulin receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of phosphatidylinositol 3-kinase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    phosphatidylinositol 3-kinase regulatory subunit alpha

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Ochotona curzoniae Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NIBS_Ocur_1.0 Primary Assembly

    Genomic

    1. NW_024465655.1 Reference NIBS_Ocur_1.0 Primary Assembly

      Range
      1775735..1857468 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040979071.1 → XP_040835005.1  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1

      Conserved Domains (5) summary
      cd09930
      Location:617 → 720
      SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
      cd09942
      Location:325 → 435
      SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
      cd11910
      Location:5 → 79
      SH3_PI3K_p85alpha; Src Homology 3 domain of the p85alpha regulatory subunit of Class IA Phosphatidylinositol 3-kinases
      cd12924
      Location:440 → 600
      iSH2_PIK3R1; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 1, PIK3R1, also called p85alpha
      cd04388
      Location:114 → 302
      RhoGAP_p85; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in the p85 isoforms of the regulatory subunit of the class IA PI3K (phosphatidylinositol 3'-kinase). This domain is also called Bcr (breakpoint cluster region protein) ...

    2. XM_040979074.1 → XP_040835008.1  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X4

      Conserved Domains (3) summary
      cd09930
      Location:317 → 420
      SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
      cd09942
      Location:25 → 135
      SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
      cd12924
      Location:140 → 300
      iSH2_PIK3R1; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 1, PIK3R1, also called p85alpha

    3. XM_040979076.1 → XP_040835010.1  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X6

      Conserved Domains (3) summary
      cd09930
      Location:309 → 412
      SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
      cd09942
      Location:76 → 186
      SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
      cl25402
      Location:191 → 292
      iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits

    4. XM_040979075.1 → XP_040835009.1  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X5

      Conserved Domains (3) summary
      cd09942
      Location:76 → 186
      SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
      cd12924
      Location:191 → 351
      iSH2_PIK3R1; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 1, PIK3R1, also called p85alpha
      cl15255
      Location:357 → 414
      SH2; Src homology 2 (SH2) domain

    5. XM_040979073.1 → XP_040835007.1  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X3

      Conserved Domains (3) summary
      cd09930
      Location:368 → 471
      SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
      cd09942
      Location:76 → 186
      SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
      cd12924
      Location:191 → 351
      iSH2_PIK3R1; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 1, PIK3R1, also called p85alpha

    6. XM_040979072.1 → XP_040835006.1  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2

      Conserved Domains (5) summary
      cd09942
      Location:325 → 435
      SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
      cd11910
      Location:5 → 79
      SH3_PI3K_p85alpha; Src Homology 3 domain of the p85alpha regulatory subunit of Class IA Phosphatidylinositol 3-kinases
      cd12924
      Location:440 → 600
      iSH2_PIK3R1; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 1, PIK3R1, also called p85alpha
      cd04388
      Location:114 → 302
      RhoGAP_p85; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in the p85 isoforms of the regulatory subunit of the class IA PI3K (phosphatidylinositol 3'-kinase). This domain is also called Bcr (breakpoint cluster region protein) ...
      cl15255
      Location:617 → 662
      SH2; Src homology 2 (SH2) domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.