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    DPYD dihydropyrimidine dehydrogenase [ Onychostruthus taczanowskii (white-rumped snowfinch) ]

    Gene ID: 121345174, updated on 3-Aug-2024

    Summary

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    Gene symbol
    DPYD
    Gene description
    dihydropyrimidine dehydrogenase
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Onychostruthus taczanowskii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Passeroidea; Passeridae; Onychostruthus
    Orthologs
    human mouse all
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    Genomic context

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    See DPYD in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    100 current ASM1759005v1 (GCF_017590055.1) Unplaced Scaffold NW_024504786.1 (16633886..16970417, complement)

    NW_024504786.1Genomic Context describing neighboring genes Neighboring gene RWD domain containing 3 Neighboring gene polypyrimidine tract binding protein 2 Neighboring gene sorting nexin 7 Neighboring gene phospholipid phosphatase related 5 Neighboring gene phospholipid phosphatase related 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_024504786 Unplaced Scaffold Reference ASM1759005v1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NADP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables dihydropyrimidine dehydrogenase (NADP+) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables iron-sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables uracil binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in thymine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in uracil catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    dihydropyrimidine dehydrogenase [NADP(+)]

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Onychostruthus taczanowskii Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM1759005v1 Primary Assembly

    Genomic

    1. NW_024504786.1 Reference ASM1759005v1 Primary Assembly

      Range
      16633886..16970417 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041421778.1 → XP_041277712.1  dihydropyrimidine dehydrogenase [NADP(+)] isoform X1

      Conserved Domains (3) summary
      COG1146
      Location:948 → 1008
      PreA; NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism]
      cd02940
      Location:532 → 834
      DHPD_FMN; Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain. DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and ...
      cl40752
      Location:53 → 511
      GltD; NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]

    2. XM_041421779.1 → XP_041277713.1  dihydropyrimidine dehydrogenase [NADP(+)] isoform X2

      Conserved Domains (3) summary
      COG1146
      Location:783 → 843
      PreA; NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism]
      cd02940
      Location:367 → 669
      DHPD_FMN; Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain. DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and ...
      cl40752
      Location:24 → 346
      GltD; NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]

    3. XM_041421780.1 → XP_041277714.1  dihydropyrimidine dehydrogenase [NADP(+)] isoform X3

      Conserved Domains (1) summary
      cl40752
      Location:53 → 508
      GltD; NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]

    4. XM_041421782.1 → XP_041277716.1  dihydropyrimidine dehydrogenase [NADP(+)] isoform X5

      Conserved Domains (1) summary
      cl40752
      Location:53 → 160
      GltD; NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]

    5. XM_041421781.1 → XP_041277715.1  dihydropyrimidine dehydrogenase [NADP(+)] isoform X4

      Conserved Domains (1) summary
      cl40752
      Location:53 → 160
      GltD; NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]

    RNA

    1. XR_005953933.1 RNA Sequence

    2. XR_005953934.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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