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    Gr64b Gustatory receptor 64b [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 117480, updated on 19-Jun-2024

    Summary

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    Official Symbol
    Gr64bprovided by FlyBase
    Official Full Name
    Gustatory receptor 64bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0045478
    Locus tag
    Dmel_CG32257
    See related
    AllianceGenome:FB:FBgn0045478
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0118547.604; CG14986; CG32257; Dmel64b; Dmel\CG32257; Gr64; GR64b
    Summary
    Enables sweet taste receptor activity. Involved in sensory perception of sweet taste. Predicted to be integral component of membrane. Is expressed in adult head; adult sensory neurons; and tarsal segment. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See Gr64b in Genome Data Viewer
    Location:
    64A4-64A4; 3-10 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4028605..4032032)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4028605..4032032)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Mitochondrial E3 ubiquitin protein ligase 1 Neighboring gene uncharacterized protein Neighboring gene Gustatory receptor 64a Neighboring gene Gustatory receptor 64c Neighboring gene antisense RNA:CR45042 Neighboring gene Gustatory receptor 64d Neighboring gene Gustatory receptor 64e Neighboring gene Gustatory receptor 64f Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Functional Agonist of Insect Olfactory Receptors: Behavior, Physiology and Structure. Batra S, et al. Front Cell Neurosci, 2019. PMID 31110474, Free PMC Article
    2. Deciphering the Genes for Taste Receptors for Fructose in Drosophila. Uchizono S, et al. Mol Cells, 2017 Oct. PMID 29047261, Free PMC Article
    3. Gr64f is required in combination with other gustatory receptors for sugar detection in Drosophila. Jiao Y, et al. Curr Biol, 2008 Nov 25. PMID 19026541, Free PMC Article
    4. Genetic Variation in Taste Sensitivity to Sugars in Drosophila melanogaster. Uchizono S, et al. Chem Senses, 2017 May 1. PMID 28164220
    5. A genetic tool kit for cellular and behavioral analyses of insect sugar receptors. Yavuz A, et al. Fly (Austin), 2014. PMID 25984594, Free PMC Article

    See all (56) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ligand-gated monoatomic ion channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables sweet taste receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sweet taste receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables taste receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables taste receptor activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus involved in sensory perception of taste IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in monoatomic ion transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in sensory perception of sweet taste IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sensory perception of sweet taste IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in sensory perception of sweet taste IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sensory perception of taste NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    gustatory receptor 64b
    Names
    CG32257-PA
    Gr64b-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      4028605..4032032
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168049.2 → NP_728921.1  gustatory receptor 64b [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728921.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P83294
      Related
      FBpp0073051
      Conserved Domains (1) summary
      pfam06151
      Location:3 → 400
      Trehalose_recp; Trehalose receptor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P83294.1 P83294

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