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    Rnf32 ring finger protein 32 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 311936, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Rnf32provided by RGD
    Official Full Name
    ring finger protein 32provided by RGD
    Primary source
    RGD:1308287
    See related
    EnsemblRapid:ENSRNOG00000005691 AllianceGenome:RGD:1308287
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable metal ion binding activity. Predicted to be located in several cellular components, including aggresome; endosome; and nuclear body. Orthologous to human RNF32 (ring finger protein 32). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Testes (RPKM 86.3), Adrenal (RPKM 45.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rnf32 in Genome Data Viewer
    Location:
    4q11
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (6822700..6884411, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (6144749..6209320, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (2053283..2113917)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene ribosomal L24 domain containing 1, pseudogene 1 Neighboring gene limb development membrane protein 1 Neighboring gene NSA2 ribosome biogenesis factor like 2 Neighboring gene uncharacterized LOC102550082

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A double RING-H2 domain in RNF32, a gene expressed during sperm formation. van Baren MJ, et al. Biochem Biophys Res Commun, 2002 Mar 22. PMID 11890671
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in aggresome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nuclear body IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    RING finger protein 32

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001395025.1 → NP_001381954.1  RING finger protein 32

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A6KJM0, F7ENQ2
      Related
      ENSRNOP00000043844.3, ENSRNOT00000045086.5
      Conserved Domains (3) summary
      cd16677
      Location:128 → 171
      RING1-H2_RNF32; RING finger 1, H2 subclass, found in RING finger protein 32 (RNF32) and similar proteins
      cd16678
      Location:294 → 361
      RING2-H2_RNF32; RING finger 2, H2 subclass, found in RING finger protein 32 (RNF32) and similar proteins
      pfam00612
      Location:190 → 209
      IQ; IQ calmodulin-binding motif

    RNA

    1. NR_172473.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      6822700..6884411 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039107490.2 → XP_038963418.1  RING finger protein 32 isoform X1

      UniProtKB/TrEMBL
      A6KJM0, F7ENQ2
      Conserved Domains (3) summary
      cd16677
      Location:128 → 171
      RING1-H2_RNF32; RING finger 1, H2 subclass, found in RING finger protein 32 (RNF32) and similar proteins
      cd16678
      Location:294 → 361
      RING2-H2_RNF32; RING finger 2, H2 subclass, found in RING finger protein 32 (RNF32) and similar proteins
      pfam00612
      Location:190 → 209
      IQ; IQ calmodulin-binding motif

    2. XM_039107488.2 → XP_038963416.1  RING finger protein 32 isoform X1

      UniProtKB/TrEMBL
      A6KJM0, F7ENQ2
      Conserved Domains (3) summary
      cd16677
      Location:128 → 171
      RING1-H2_RNF32; RING finger 1, H2 subclass, found in RING finger protein 32 (RNF32) and similar proteins
      cd16678
      Location:294 → 361
      RING2-H2_RNF32; RING finger 2, H2 subclass, found in RING finger protein 32 (RNF32) and similar proteins
      pfam00612
      Location:190 → 209
      IQ; IQ calmodulin-binding motif

    3. XM_006235853.5 → XP_006235915.1  RING finger protein 32 isoform X1

      See identical proteins and their annotated locations for XP_006235915.1

      UniProtKB/TrEMBL
      A6KJM0, F7ENQ2
      Conserved Domains (3) summary
      cd16677
      Location:128 → 171
      RING1-H2_RNF32; RING finger 1, H2 subclass, found in RING finger protein 32 (RNF32) and similar proteins
      cd16678
      Location:294 → 361
      RING2-H2_RNF32; RING finger 2, H2 subclass, found in RING finger protein 32 (RNF32) and similar proteins
      pfam00612
      Location:190 → 209
      IQ; IQ calmodulin-binding motif

    4. XM_063285932.1 → XP_063142002.1  RING finger protein 32 isoform X3

    5. XM_063285931.1 → XP_063142001.1  RING finger protein 32 isoform X2

    6. XM_006235854.4 → XP_006235916.1  RING finger protein 32 isoform X1

      See identical proteins and their annotated locations for XP_006235916.1

      UniProtKB/TrEMBL
      A6KJM0, F7ENQ2
      Conserved Domains (3) summary
      cd16677
      Location:128 → 171
      RING1-H2_RNF32; RING finger 1, H2 subclass, found in RING finger protein 32 (RNF32) and similar proteins
      cd16678
      Location:294 → 361
      RING2-H2_RNF32; RING finger 2, H2 subclass, found in RING finger protein 32 (RNF32) and similar proteins
      pfam00612
      Location:190 → 209
      IQ; IQ calmodulin-binding motif

    7. XM_063285930.1 → XP_063142000.1  RING finger protein 32 isoform X1

      UniProtKB/TrEMBL
      A6KJM0, F7ENQ2

    8. XM_063285929.1 → XP_063141999.1  RING finger protein 32 isoform X1

      UniProtKB/TrEMBL
      A6KJM0, F7ENQ2

    9. XM_039107489.2 → XP_038963417.1  RING finger protein 32 isoform X1

      UniProtKB/TrEMBL
      A6KJM0, F7ENQ2
      Conserved Domains (3) summary
      cd16677
      Location:128 → 171
      RING1-H2_RNF32; RING finger 1, H2 subclass, found in RING finger protein 32 (RNF32) and similar proteins
      cd16678
      Location:294 → 361
      RING2-H2_RNF32; RING finger 2, H2 subclass, found in RING finger protein 32 (RNF32) and similar proteins
      pfam00612
      Location:190 → 209
      IQ; IQ calmodulin-binding motif

    10. XM_039107487.2 → XP_038963415.1  RING finger protein 32 isoform X1

      UniProtKB/TrEMBL
      A6KJM0, F7ENQ2
      Conserved Domains (3) summary
      cd16677
      Location:128 → 171
      RING1-H2_RNF32; RING finger 1, H2 subclass, found in RING finger protein 32 (RNF32) and similar proteins
      cd16678
      Location:294 → 361
      RING2-H2_RNF32; RING finger 2, H2 subclass, found in RING finger protein 32 (RNF32) and similar proteins
      pfam00612
      Location:190 → 209
      IQ; IQ calmodulin-binding motif

    11. XM_017592602.3 → XP_017448091.1  RING finger protein 32 isoform X1

      UniProtKB/TrEMBL
      A6KJM0, F7ENQ2
      Conserved Domains (3) summary
      cd16677
      Location:128 → 171
      RING1-H2_RNF32; RING finger 1, H2 subclass, found in RING finger protein 32 (RNF32) and similar proteins
      cd16678
      Location:294 → 361
      RING2-H2_RNF32; RING finger 2, H2 subclass, found in RING finger protein 32 (RNF32) and similar proteins
      pfam00612
      Location:190 → 209
      IQ; IQ calmodulin-binding motif

    12. XM_039107491.2 → XP_038963419.1  RING finger protein 32 isoform X6

      Conserved Domains (1) summary
      cd16677
      Location:128 → 171
      RING1-H2_RNF32; RING finger 1, H2 subclass, found in RING finger protein 32 (RNF32) and similar proteins

    13. XM_017592606.3 → XP_017448095.1  RING finger protein 32 isoform X5

      UniProtKB/TrEMBL
      D4A0T7, Q5XIP3

    14. XM_063285935.1 → XP_063142005.1  RING finger protein 32 isoform X5

      Related
      ENSRNOP00000007646.9, ENSRNOT00000007646.10

    15. XM_017592605.3 → XP_017448094.1  RING finger protein 32 isoform X4

      UniProtKB/TrEMBL
      D4A0T7, Q5XIP3

    16. XM_063285933.1 → XP_063142003.1  RING finger protein 32 isoform X4

    17. XM_063285934.1 → XP_063142004.1  RING finger protein 32 isoform X4

    18. XM_063285936.1 → XP_063142006.1  RING finger protein 32 isoform X7

    RNA

    1. XR_005503207.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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