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    HIPK2 homeodomain interacting protein kinase 2 [ Felis catus (domestic cat) ]

    Gene ID: 101081031, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HIPK2
    Official Full Name
    homeodomain interacting protein kinase 2
    Primary source
    VGNC:VGNC:62820
    See related
    EnsemblRapid:ENSFCTG00005022096
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Felis catus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
    Orthologs
    human mouse all
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    Genomic context

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    See HIPK2 in Genome Data Viewer
    Location:
    chromosome: A2
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) A2 NC_058369.1 (154264005..154454270, complement)
    104 previous assembly Felis_catus_9.0 (GCF_000181335.3) A2 NC_018724.3 (156053510..156243509, complement)

    Chromosome A2 - NC_058369.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC123384052 Neighboring gene uncharacterized LOC109497642 Neighboring gene uncharacterized LOC111559545 Neighboring gene uncharacterized LOC102900795 Neighboring gene C-type lectin domain family 2 member L Neighboring gene uncharacterized LOC123384053 Neighboring gene uncharacterized LOC109497645 Neighboring gene thromboxane A synthase 1 Neighboring gene poly(ADP-ribose) polymerase family member 12

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables SMAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription coactivator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-threonine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in smoothened signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in PML body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    homeodomain-interacting protein kinase 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference F.catus_Fca126_mat1.0 Primary Assembly

    Genomic

    1. NC_058369.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

      Range
      154264005..154454270 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_045052836.1 → XP_044908771.1  homeodomain-interacting protein kinase 2 isoform X2

      UniProtKB/TrEMBL
      M3WDI1
      Conserved Domains (1) summary
      cd14227
      Location:183 → 537
      STKc_HIPK2; Catalytic domain of the Serine/Threonine Kinase, Homeodomain-Interacting Protein Kinase 2

    2. XM_023250619.2 → XP_023106387.2  homeodomain-interacting protein kinase 2 isoform X3

      UniProtKB/TrEMBL
      M3WDI1
      Conserved Domains (1) summary
      cd14227
      Location:183 → 537
      STKc_HIPK2; Catalytic domain of the Serine/Threonine Kinase, Homeodomain-Interacting Protein Kinase 2

    3. XM_023250618.2 → XP_023106386.2  homeodomain-interacting protein kinase 2 isoform X1

      UniProtKB/TrEMBL
      M3WDI1
      Conserved Domains (1) summary
      cd14227
      Location:183 → 537
      STKc_HIPK2; Catalytic domain of the Serine/Threonine Kinase, Homeodomain-Interacting Protein Kinase 2

    4. XM_045052839.1 → XP_044908774.1  homeodomain-interacting protein kinase 2 isoform X7

      UniProtKB/TrEMBL
      M3WDI1
      Conserved Domains (1) summary
      cd14227
      Location:183 → 537
      STKc_HIPK2; Catalytic domain of the Serine/Threonine Kinase, Homeodomain-Interacting Protein Kinase 2

    5. XM_045052837.1 → XP_044908772.1  homeodomain-interacting protein kinase 2 isoform X5

      UniProtKB/TrEMBL
      M3WDI1
      Conserved Domains (1) summary
      cd14227
      Location:183 → 537
      STKc_HIPK2; Catalytic domain of the Serine/Threonine Kinase, Homeodomain-Interacting Protein Kinase 2

    6. XM_023250621.2 → XP_023106389.2  homeodomain-interacting protein kinase 2 isoform X6

      UniProtKB/TrEMBL
      M3WDI1
      Related
      ENSFCTP00005046410.1, ENSFCTT00005063800.1
      Conserved Domains (1) summary
      cd14227
      Location:183 → 537
      STKc_HIPK2; Catalytic domain of the Serine/Threonine Kinase, Homeodomain-Interacting Protein Kinase 2

    7. XM_023250620.2 → XP_023106388.2  homeodomain-interacting protein kinase 2 isoform X4

      UniProtKB/TrEMBL
      M3WDI1
      Related
      ENSFCTP00005046618.1, ENSFCTT00005064138.1
      Conserved Domains (1) summary
      cd14227
      Location:183 → 537
      STKc_HIPK2; Catalytic domain of the Serine/Threonine Kinase, Homeodomain-Interacting Protein Kinase 2
    Nucleotide Protein
    Heading Accession and Version

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