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    RNF14 ring finger protein 14 [ Homo sapiens (human) ]

    Gene ID: 9604, updated on 2-Nov-2024

    Summary

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    Official Symbol
    RNF14provided by HGNC
    Official Full Name
    ring finger protein 14provided by HGNC
    Primary source
    HGNC:HGNC:10058
    See related
    Ensembl:ENSG00000013561 MIM:605675; AllianceGenome:HGNC:10058
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ARA54; HFB30; TRIAD2; HRIHFB2038
    Summary
    The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq, Jan 2011]
    Expression
    Ubiquitous expression in testis (RPKM 10.0), thyroid (RPKM 8.1) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See RNF14 in Genome Data Viewer
    Location:
    5q31.3
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (141949337..141990292)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (142475299..142516212)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (141346408..141369857)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene glycine cleavage system protein H (aminomethyl carrier) pseudogene Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:141293283-141293820 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:141303317-141303830 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:141308886-141309386 Neighboring gene DAP3 binding cell death enhancer 1 Neighboring gene protocadherin 12 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:141336627-141337533 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:141337534-141338439 Neighboring gene uncharacterized LOC124901095 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16464 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23314 Neighboring gene glucosamine-6-phosphate deaminase 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16465 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16466 Neighboring gene CRISPRi-validated cis-regulatory element chr5.3497 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23315 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16467 Neighboring gene Sharpr-MPRA regulatory region 4900 Neighboring gene mitochondrial ribosomal protein L11 pseudogene 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. ARA54 is involved in transcriptional regulation of the cyclin D1 gene in human cancer cells. Kikuchi H, et al. Carcinogenesis, 2007 Aug. PMID 17510080
    2. Isolation and characterization of a novel human gene (HFB30) which encodes a protein with a RING finger motif. Ueki N, et al. Biochim Biophys Acta, 1999 May 14. PMID 10320776
    3. Expression of androgen receptor coactivators in normal and cancer prostate tissues and cultured cell lines. Mestayer C, et al. Prostate, 2003 Aug 1. PMID 12772188
    4. Neuropathy Target Esterase Is Degraded by the Ubiquitin-Proteasome Pathway with ARA54 as the Ubiquitin Ligase. Long DX, et al. Biochemistry, 2015 Dec 22. PMID 26606397
    5. A dominant-negative mutant of androgen receptor coregulator ARA54 inhibits androgen receptor-mediated prostate cancer growth. Miyamoto H, et al. J Biol Chem, 2002 Feb 15. PMID 11673464

    See all (52) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. RNF14-dependent atypical ubiquitylation promotes translation-coupled resolution of RNA-protein crosslinks.
      Title: RNF14-dependent atypical ubiquitylation promotes translation-coupled resolution of RNA-protein crosslinks.
    2. Ring Finger Protein 14 (RNF14) is a binding partner for all TCF/LEF transcription factors.
      Title: Ring Finger Protein 14 is a new regulator of TCF/β-catenin-mediated transcription and colon cancer cell survival.
    3. Differential localization of ARA54 may play an important role in testicular development and spermatogenesis in humans.
      Title: Expression of androgen receptor co-regulators in the testes of men with azoospermia.
    4. mRNA expression of ARA54 correlates with that of cyclin D1 in human colon carcinoma cells, indicating that ARA54 is not only involved in the regulation of cyclin D1 expression in cultured cell lines but also in clinical cancer specimens.
      Title: ARA54 is involved in transcriptional regulation of the cyclin D1 gene in human cancer cells.
    5. ARA54, might have dual in vivo roles functioning as both a direct coactivator and as an indirect mediator in AR function.
      Title: Transgelin functions as a suppressor via inhibition of ARA54-enhanced androgen receptor transactivation and prostate cancer cell growth.
    6. ARA54 role in prostate carcinoma progression may in may involve function as androgen receptor coactivator and focal adhesion protein
      Title: Expression of androgen receptor coactivators in normal and cancer prostate tissues and cultured cell lines.
    7. Dual functional roles for ARA54 as an AR coregulator directly and as a mediator for the suppressive effect of hnRNP A1 indirectly.
      Title: Suppression of androgen receptor transactivation and prostate cancer cell growth by heterogeneous nuclear ribonucleoprotein A1 via interaction with androgen receptor coregulator ARA54.
    8. dominant-negative AR coregulator can suppress AR transactivation and cell proliferation in prostate cancer cells
      Title: A dominant-negative mutant of androgen receptor coregulator ARA54 inhibits androgen receptor-mediated prostate cancer growth.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See Variation Viewer (GRCh37.p13)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ26004

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables nuclear androgen receptor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription coactivator activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables ubiquitin conjugating enzyme binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin protein ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ubiquitin-like protein transferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in androgen receptor signaling pathway NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in positive regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein K6-linked ubiquitination IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein ubiquitination IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in protein-RNA covalent cross-linking repair IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of androgen receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of canonical Wnt signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in rescue of stalled ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in signal transduction TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ubiquitin-dependent protein catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		  
    is_active_in cytosolic ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase RNF14
    Names
    androgen receptor associated protein 54
    NP_001188294.1
    NP_004281.1
    NP_899645.1
    NP_899646.1
    NP_899647.1
    NP_899648.1
    XP_011536016.1
    XP_016865563.1
    XP_016865564.1
    XP_024302033.1
    XP_047273854.1
    XP_047273855.1
    XP_047273856.1
    XP_047273857.1
    XP_047273858.1
    XP_047273859.1
    XP_047273860.1
    XP_047273861.1
    XP_047273862.1
    XP_047273863.1
    XP_047273864.1
    XP_047273865.1
    XP_047273866.1
    XP_054209813.1
    XP_054209814.1
    XP_054209815.1
    XP_054209816.1
    XP_054209817.1
    XP_054209818.1
    XP_054209819.1
    XP_054209820.1
    XP_054209821.1
    XP_054209822.1
    XP_054209823.1
    XP_054209824.1
    XP_054209825.1
    XP_054209826.1
    XP_054209827.1
    XP_054209828.1
    XP_054209829.1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001201365.2 → NP_001188294.1  E3 ubiquitin-protein ligase RNF14 isoform 1

      See identical proteins and their annotated locations for NP_001188294.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Both variants encode the same isoform (1).
      Source sequence(s)
      AC005740, BC126185, BE042895, DC396586
      Consensus CDS
      CCDS4270.1
      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8
      UniProtKB/TrEMBL
      B3KN55
      Related
      ENSP00000378027.1, ENST00000394519.5
      Conserved Domains (4) summary
      smart00647
      Location:289 → 350
      IBR; In Between Ring fingers
      pfam01485
      Location:377 → 433
      IBR; IBR domain, a half RING-finger domain
      pfam05773
      Location:7 → 133
      RWD; RWD domain
      cd16628
      Location:218 → 271
      RING-HC_RBR_RNF14; RING finger, HC subclass, found in RING finger protein 14 (RNF14) and similar proteins

    2. NM_004290.5 → NP_004281.1  E3 ubiquitin-protein ligase RNF14 isoform 1

      See identical proteins and their annotated locations for NP_004281.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC005740, AF060544, BE042895, DC402536
      Consensus CDS
      CCDS4270.1
      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8
      UniProtKB/TrEMBL
      B3KN55
      Related
      ENSP00000378028.2, ENST00000394520.7
      Conserved Domains (4) summary
      smart00647
      Location:289 → 350
      IBR; In Between Ring fingers
      pfam01485
      Location:377 → 433
      IBR; IBR domain, a half RING-finger domain
      pfam05773
      Location:7 → 133
      RWD; RWD domain
      cd16628
      Location:218 → 271
      RING-HC_RBR_RNF14; RING finger, HC subclass, found in RING finger protein 14 (RNF14) and similar proteins

    3. NM_183398.3 → NP_899645.1  E3 ubiquitin-protein ligase RNF14 isoform 2

      See identical proteins and their annotated locations for NP_899645.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks an exon compared to variant 1. The translation begins at a downstream start codon and results in an isoform (2) that has a shorter N-terminus, as compared to isoform 1.
      Source sequence(s)
      AC005740, AF060544, BE042895, DB456366, DC402536
      Consensus CDS
      CCDS4271.1
      UniProtKB/Swiss-Prot
      Q9UBS8
      Related
      ENSP00000378022.2, ENST00000394514.6
      Conserved Domains (3) summary
      smart00647
      Location:163 → 224
      IBR; In Between Ring fingers
      cd16628
      Location:92 → 145
      RING-HC_RBR_RNF14; RING finger, HC subclass, found in RING finger protein 14 (RNF14) and similar proteins
      pfam01485
      Location:251 → 307
      IBR; IBR domain, a half RING-finger domain

    4. NM_183399.3 → NP_899646.1  E3 ubiquitin-protein ligase RNF14 isoform 1

      See identical proteins and their annotated locations for NP_899646.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Both variants encode the same isoform (1).
      Source sequence(s)
      AC005740, AF060544, BE042895, DC396586
      Consensus CDS
      CCDS4270.1
      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8
      UniProtKB/TrEMBL
      B3KN55
      Related
      ENSP00000348462.1, ENST00000356143.5
      Conserved Domains (4) summary
      smart00647
      Location:289 → 350
      IBR; In Between Ring fingers
      pfam01485
      Location:377 → 433
      IBR; IBR domain, a half RING-finger domain
      pfam05773
      Location:7 → 133
      RWD; RWD domain
      cd16628
      Location:218 → 271
      RING-HC_RBR_RNF14; RING finger, HC subclass, found in RING finger protein 14 (RNF14) and similar proteins

    5. NM_183400.3 → NP_899647.1  E3 ubiquitin-protein ligase RNF14 isoform 1

      See identical proteins and their annotated locations for NP_899647.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) lacks a segment within the 5' UTR compared to variant 1. Both variants encode the same isoform (1).
      Source sequence(s)
      AC005740, AF060544, BE042895, DC402536
      Consensus CDS
      CCDS4270.1
      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8
      UniProtKB/TrEMBL
      B3KN55
      Related
      ENSP00000324956.3, ENST00000347642.7
      Conserved Domains (4) summary
      smart00647
      Location:289 → 350
      IBR; In Between Ring fingers
      pfam01485
      Location:377 → 433
      IBR; IBR domain, a half RING-finger domain
      pfam05773
      Location:7 → 133
      RWD; RWD domain
      cd16628
      Location:218 → 271
      RING-HC_RBR_RNF14; RING finger, HC subclass, found in RING finger protein 14 (RNF14) and similar proteins

    6. NM_183401.3 → NP_899648.1  E3 ubiquitin-protein ligase RNF14 isoform 1

      See identical proteins and their annotated locations for NP_899648.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Both variants encode the same isoform (1).
      Source sequence(s)
      AC005740, AF060544, BE042895, DC358984
      Consensus CDS
      CCDS4270.1
      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8
      UniProtKB/TrEMBL
      B3KN55
      Conserved Domains (4) summary
      smart00647
      Location:289 → 350
      IBR; In Between Ring fingers
      pfam01485
      Location:377 → 433
      IBR; IBR domain, a half RING-finger domain
      pfam05773
      Location:7 → 133
      RWD; RWD domain
      cd16628
      Location:218 → 271
      RING-HC_RBR_RNF14; RING finger, HC subclass, found in RING finger protein 14 (RNF14) and similar proteins

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      141949337..141990292
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047417908.1 → XP_047273864.1  E3 ubiquitin-protein ligase RNF14 isoform X2

      UniProtKB/TrEMBL
      B7Z229

    2. XM_047417904.1 → XP_047273860.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8

    3. XM_047417903.1 → XP_047273859.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8

    4. XM_047417899.1 → XP_047273855.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8

    5. XM_047417907.1 → XP_047273863.1  E3 ubiquitin-protein ligase RNF14 isoform X2

      UniProtKB/TrEMBL
      B7Z229

    6. XM_047417898.1 → XP_047273854.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8

    7. XM_047417906.1 → XP_047273862.1  E3 ubiquitin-protein ligase RNF14 isoform X2

      UniProtKB/TrEMBL
      B7Z229

    8. XM_047417905.1 → XP_047273861.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8

    9. XM_047417909.1 → XP_047273865.1  E3 ubiquitin-protein ligase RNF14 isoform X2

      UniProtKB/TrEMBL
      B7Z229

    10. XM_024446265.2 → XP_024302033.1  E3 ubiquitin-protein ligase RNF14 isoform X2

      UniProtKB/TrEMBL
      B7Z229
      Conserved Domains (3) summary
      smart00647
      Location:113 → 174
      IBR; In Between Ring fingers
      pfam01485
      Location:201 → 257
      IBR; IBR domain, a half RING-finger domain
      cl02687
      Location:7 → 79
      RWD; RWD domain

    11. XM_047417902.1 → XP_047273858.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8

    12. XM_017010075.3 → XP_016865564.1  E3 ubiquitin-protein ligase RNF14 isoform X2

      UniProtKB/TrEMBL
      B7Z229
      Conserved Domains (3) summary
      smart00647
      Location:113 → 174
      IBR; In Between Ring fingers
      pfam01485
      Location:201 → 257
      IBR; IBR domain, a half RING-finger domain
      cl02687
      Location:7 → 79
      RWD; RWD domain

    13. XM_047417900.1 → XP_047273856.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8

    14. XM_047417901.1 → XP_047273857.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8

    15. XM_011537714.4 → XP_011536016.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      See identical proteins and their annotated locations for XP_011536016.1

      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8
      UniProtKB/TrEMBL
      B3KN55
      Conserved Domains (4) summary
      smart00647
      Location:289 → 350
      IBR; In Between Ring fingers
      pfam01485
      Location:377 → 433
      IBR; IBR domain, a half RING-finger domain
      pfam05773
      Location:7 → 133
      RWD; RWD domain
      cd16628
      Location:218 → 271
      RING-HC_RBR_RNF14; RING finger, HC subclass, found in RING finger protein 14 (RNF14) and similar proteins

    16. XM_047417910.1 → XP_047273866.1  E3 ubiquitin-protein ligase RNF14 isoform X2

      UniProtKB/TrEMBL
      B7Z229

    17. XM_017010074.3 → XP_016865563.1  E3 ubiquitin-protein ligase RNF14 isoform X2

      UniProtKB/TrEMBL
      B7Z229
      Conserved Domains (3) summary
      smart00647
      Location:113 → 174
      IBR; In Between Ring fingers
      pfam01485
      Location:201 → 257
      IBR; IBR domain, a half RING-finger domain
      cl02687
      Location:7 → 79
      RWD; RWD domain

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      142475299..142516212
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054353851.1 → XP_054209826.1  E3 ubiquitin-protein ligase RNF14 isoform X2

      UniProtKB/TrEMBL
      B7Z229

    2. XM_054353843.1 → XP_054209818.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8

    3. XM_054353842.1 → XP_054209817.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8

    4. XM_054353839.1 → XP_054209814.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8

    5. XM_054353848.1 → XP_054209823.1  E3 ubiquitin-protein ligase RNF14 isoform X2

      UniProtKB/TrEMBL
      B7Z229

    6. XM_054353838.1 → XP_054209813.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8

    7. XM_054353847.1 → XP_054209822.1  E3 ubiquitin-protein ligase RNF14 isoform X2

      UniProtKB/TrEMBL
      B7Z229

    8. XM_054353844.1 → XP_054209819.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8

    9. XM_054353853.1 → XP_054209828.1  E3 ubiquitin-protein ligase RNF14 isoform X2

      UniProtKB/TrEMBL
      B7Z229

    10. XM_054353850.1 → XP_054209825.1  E3 ubiquitin-protein ligase RNF14 isoform X2

      UniProtKB/TrEMBL
      B7Z229

    11. XM_054353841.1 → XP_054209816.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8

    12. XM_054353852.1 → XP_054209827.1  E3 ubiquitin-protein ligase RNF14 isoform X2

      UniProtKB/TrEMBL
      B7Z229

    13. XM_054353845.1 → XP_054209820.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8

    14. XM_054353854.1 → XP_054209829.1  E3 ubiquitin-protein ligase RNF14 isoform X2

      UniProtKB/TrEMBL
      B7Z229

    15. XM_054353840.1 → XP_054209815.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8

    16. XM_054353846.1 → XP_054209821.1  E3 ubiquitin-protein ligase RNF14 isoform X1

      UniProtKB/Swiss-Prot
      A0AV26, A6NMR2, A8MTW5, B3KN72, B7ZLV2, D3DQE4, O94793, Q6IBV0, Q9UBS8

    17. XM_054353849.1 → XP_054209824.1  E3 ubiquitin-protein ligase RNF14 isoform X2

      UniProtKB/TrEMBL
      B7Z229
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9UBS8.1 GenPept UniProtKB/Swiss-Prot:Q9UBS8

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