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    Olig1 oligodendrocyte transcription factor 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 60394, updated on 2-Nov-2024

    Summary

    Official Symbol
    Olig1provided by RGD
    Official Full Name
    oligodendrocyte transcription factor 1provided by RGD
    Primary source
    RGD:621129
    See related
    EnsemblRapid:ENSRNOG00000028648 AllianceGenome:RGD:621129
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Olg1; oligo1
    Summary
    This gene is a member of the oligodendrocyte lineage gene family which encode basic helix-loop-helix transcription factors. Studies in mice show that it is coexpressed with Olig2 in neural progenitors, and has a role in the development and maturation of oligodendrocytes. [provided by RefSeq, Jul 2008]
    Orthologs
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    Genomic context

    See Olig1 in Genome Data Viewer
    Location:
    11q11
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (44000450..44002592)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (30514379..30516521)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (31428377..31430519)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134481054 Neighboring gene oligodendrocyte transcription factor 2 Neighboring gene uncharacterized LOC120095614 Neighboring gene uncharacterized LOC134481055

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific  
    enables E-box binding  
    enables protein dimerization activity  
    Process Evidence Code Pubs
    involved_in axon development  
    involved_in neuron fate commitment  
    acts_upstream_of_or_within neuron fate commitment  
    involved_in oligodendrocyte development  
    involved_in oligodendrocyte development  
    involved_in positive regulation of transcription by RNA polymerase II  
    involved_in sensory organ development  
    Component Evidence Code Pubs
    is_active_in nucleus  

    General protein information

    Preferred Names
    oligodendrocyte transcription factor 1
    Names
    Olg-1 bHLH protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021770.4NP_068538.2  oligodendrocyte transcription factor 1

      See identical proteins and their annotated locations for NP_068538.2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/Swiss-Prot
      Q9WUQ3
      UniProtKB/TrEMBL
      A0A0H2UHA2, A6JLE8
      Related
      ENSRNOP00000002827.6, ENSRNOT00000002827.9
      Conserved Domains (1) summary
      cd18942
      Location:96165
      bHLH_TS_OLIG1; basic helix-loop-helix (bHLH) domain found in oligodendrocyte transcription factor 1 (Oligo1) and similar proteins

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      44000450..44002592
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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